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Zinc Enzymes for Drug Design and Drug Development

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".

Deadline for manuscript submissions: 30 May 2024 | Viewed by 334

Special Issue Editors


E-Mail Website
Guest Editor
Istituto di Biostrutture e Bioimmagini, CNR, Via Pietro Castellino 111, 80131 Napoli, Italy
Interests: structural biology; protein crystallography; drug design; carbonyc anhydrases
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Istituto di Biostrutture e Bioimmagini, CNR, Via Pietro Castellino 111, 80131 Napoli, Italy
Interests: structural biology; X-ray crystallography; biochemistry
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institute of Biostructures and Bioimaging-CNR, Via Pietro Castellino 111, 80131 Naples, Italy
Interests: structural biology; X-ray crystallography; proteins; protein-ligand complexes
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Zinc is an essential transition metal necessary for the activity of many enzymes involved in important biological functions. For this reason, many zinc-containing enzymes, such as Carbonic Anhydrases (CAs), Matrix Metalloproteinases (MMPs), and Histone deacetylases (HDACs), have in recent years garnered great interest as therapeutic targets for treating a wide variety of human diseases, and many successful examples of drug design studies directed at these molecules are available. In this issue, we will summarize the most important results obtained in this field and provide future perspectives for developing novel drug classes targeting zinc metalloenzymes.

Dr. Giuseppina De Simone
Dr. Anna Di Fiore
Dr. Vincenzo Alterio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • zinc enzymes
  • carbonic anhydrases
  • matrix metalloproteinases
  • histone deacetylases
  • zinc metalloenzymes
  • drug design

Published Papers

This special issue is now open for submission.
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