Immune Defense Mechanisms of the External, Middle, and Inner Ear

Dear Colleagues,

While immune responses are essential for protecting the ear from infection and injury, excessive or dysregulated immune activation may lead to pathological conditions. One example is autoimmune inner ear disease (AIED), in which abnormal immune responses target inner ear structures. This condition may result in sensorineural hearing loss and vestibular symptoms such as dizziness or imbalance. In such cases, immunosuppressive therapies, particularly corticosteroids, are commonly used to reduce inflammation and preserve auditory function.

Scope of the Special Issue

This Special Issue aims to provide a platform for advancing knowledge in ear immunology. We welcome submissions including review articles, basic research studies, clinical investigations, and case reports addressing immune mechanisms of the ear, immune-mediated ear diseases, and emerging therapeutic strategies. Contributions from multidisciplinary perspectives are encouraged to further elucidate the complex interactions between the immune system and auditory function.

Researchers and clinicians working in the fields of otolaryngology, immunology, neuroscience, and related disciplines are warmly invited to submit their work.

Prof. Dr. Chul Ho Jang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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