Neuroimmune Regulation of Acute and Chronic Pain

Dear Colleagues,

The following Special Issue focuses on the bidirectional relationship of the immune and nervous systems in the modulation of acute and chronic pain. We hope to provide readers with an overview of the topic including articles that describe the relationship between neurons and CNS resident (glial and mast) immune cells as well as infiltrating T-cells in the pathophysiology of pain. Additional topics of interest include neurovascular coupling and the status of the blood–brain barrier in the regulation of neuroinflammation given its contribution to chronic pain and the recently recognized relationship between the enteric nervous and immune systems which plays a role in neuromodulation via both humoral and neuronal mechanisms. Catecholamine production and stress responses that impact chronic pain conditions are also relevant. We invite submissions investigating these diverse neuroimmune mechanisms as they relate to pain pathophysiology. Lastly, the journal welcomes molecular science and clinical or pure model submissions including biomolecular experiments.

Dr. Karen M. Wagner
Guest Editor

Manuscript Submission Information

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