Medicinal Chemistry: Design, Synthesis and Application
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 January 2027 | Viewed by 62
Editor
Interests: medicinal chemistry; photodynamic therapy; combined therapy; conjugated drugs; photosensitizers; photochemistry; targeted therapy for cancer; organic chemistry
Special Issue Information
Dear Colleagues,
Medicinal chemistry is a rapidly evolving interdisciplinary field that integrates synthetic chemistry, molecular design, chemical biology, and pharmaceutical sciences to address current challenges in human health. Advances in synthetic methodologies, computational tools, structural biology, and molecular pharmacology continue to accelerate the discovery and optimization of novel therapeutic agents with improved efficacy, selectivity, and safety. This Special Issue aims to provide a platform for the latest developments in the design, synthesis, characterization, and biological evaluation of molecules with therapeutic potential. We welcome the contribution of original research articles and comprehensive reviews covering a broad range of topics, including rational drug design, synthetic and medicinal chemistry, bioactive natural products and their derivatives, heterocyclic and peptide chemistry, molecular probes, chemical biology, computational medicinal chemistry, structure–activity relationship studies, drug delivery strategies, prodrugs, biomolecular conjugates, and the development of compounds targeting cancer, infectious diseases, inflammatory disorders, metabolic diseases, neurological disorders, and other human pathologies. Studies on innovative synthetic methodologies, screening approaches, pharmacokinetics, and early-stage drug discovery are also encouraged. By collating contributions from diverse areas of medicinal chemistry, this Special Issue aims to present recent advances, stimulate interdisciplinary collaboration, and provide insights into future directions in the discovery and development of next-generation therapeutic agents.
Dr. Vasilii Otvagin
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
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Keywords
- medicinal chemistry
- drug design
- synthesis and analysis
- biological chemistry
- bioactive natural products
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