Genetic Basis and Molecular Mechanisms of Heart Rhythm Disorders

Dear Colleagues,

Among the inherited ion channelopathies associated with potentially life-threatening ventricular arrhythmia syndromes in nominally structurally normal hearts are the J-wave syndromes, which include the Brugada (BrS) and early repolarization (ERS) syndromes. These ion channelopathies are responsible for sudden cardiac death (SCD), most often in young adults in the third and fourth decade of life. Although great progress has been made in the past few decades, the genetic basis and molecular mechanisms for such syndromes remains largely unclear.

This Special Issue will focus on basic research on cellular and animal models and patient data and samples, and will collect reviews and original research articles that expand knowledge in the field of J-wave syndromes linked with life-threatening ventricular arrhythmias and sudden cardiac death. Potential topics include, but are not limited to, the contribution of the molecular, ionic, cellular, and genetic mechanisms underlying these primary electrical diseases.

Dr. Hector Barajas-Martinez
Guest Editor

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