Choroid Plexus: Novel Functions for an Old Structure

Dear colleagues,

Interest in the roles of the choroid plexus has noticeably increased in recent years.

The choroid plexus is a set of highly vascularized structures, located in the ventricular system of the brain that functions as a barrier at the interface between the blood and the cerebrospinal fluid.

The best-known functions of the choroid plexus are cerebrospinal fluid production and secretion, nutrient and hormone supply to the cerebrospinal fluid and brain, clearance of deleterious compounds and waste products, neuroimmune regulation, and stem cell proliferation and differentiation. Interestingly, emerging functions of the choroid plexus in the chemical surveillance of the central nervous system and as an extra-suprachiasmatic nucleus circadian clock highlight the possibility of sensing alterations in both the cerebrospinal and blood side, reacting to them in order to ensure brain homeostasis.

The implication of these new functions in the pathophysiology of the central nervous system deserves more attention.

Dr. Cecília R. Santos
Dr. Telma Quintela
Dr. Isabel Goncalves
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.