The Carcinogenetic Potential of Human Papilloma Virus: From Experimental Studies to Targeted Therapy

Dear Colleagues,

The scope of this special issue is to collect papers referring to the carcinogenic role of Human Papilloma virus (HPV). It is known to be involved in genesis of cervical cancer, anal canal but also head and neck malignancies but the exact role in pathogenesis and evolution of these carcinomas is far to be understood. Moreover, although p16 is used as the surrogate marker in immunohistochemistry, as a tool for identification of HPV mutations, the PCR determinations do not confirm in any case the association between gene status and protein expression. Based on this fact, a deeply examination of HPV interactions and carcinogenic potential deserves attention. The prognostic and predictive role of HPV in oncology patients is also worthy to be explored. Any review or original-type article is welcome, including experimental, basic research or clinical data. If some papers are mainly based on in silico analysis or examination of public gene databases, they should include an external validation on own cohort. We hope to collect interesting papers that help researchers to have a better understanding of HPV and medical doctors to have an whole picture  of HPV, from carcinogenesis to drug resistance.

Prof. Dr. Simona Gurzu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• human papilloma virus
• head and neck cancer
• squamous cell carcinoma
• oropharyngeal cancer
• non-oropharyngeal malignancies
• anal canal
• uterine cervix
• tumor tissue
• PCR
• NGS
• oncology
• pathology
• carcinogenesis