Molecular Research Progress of Inherited Cardiomyopathies

Dear Colleagues,

The heart is one of the earliest-forming organs during development, and many genes contribute to its morphogenesis and function. Consequently, the diversity of genetic disorders that manifest with cardiomyopathic dysfunction is extensive. Functionally, defects in transcription, signaling, mitochondrial function, metabolism, cellular architecture, autophagy, chaperone function and other molecular and cellular processes have been implicated. Strategies to treat inherited disorders range from gene and enzyme replacement therapy to molecules that attenuate the consequences of primary gene dysfunction. Mechanisms of inherited cardiomyopathy gene dysfunction are sometimes relevant in acquired cardiomyopathies as well. For many inherited cardiomyopathies, however, disease-targeted therapy remains an elusive goal and ongoing unmet need. Understanding the molecular basis of inherited cardiomyopathies will provide wide-ranging insights into the mechanisms of cardiovascular disease and provide opportunities for better therapeutic targeting.

Prof. Dr. Michael T. Chin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.