Molecular Biology of Nuclear Receptors 4.0

Dear Colleagues,

Nuclear receptors include steroid/thyroid hormone receptors, metabolic sensors and orphan receptors. Metabolic sensor-type nuclear receptors, such as liver X receptor, farnesoid X receptor and peroxisome proliferator activator receptor (PPAR), are activated by oxysterol, bile acid and fatty acid, and regulate their metabolism. These receptors, like steroid hormone receptors, also regulate cellular proliferation/differentiation, and immunity. Dysregulation in these systems has been implicated in the pathogenesis of human diseases, such as cancer, cardiovascular disease, and inflammation. Moreover, nuclear receptors including PPAR, retinoid receptors, and several orphan receptors have recently been known to be involved in the etiology of metabolic syndrome and atherosclerosis. In this Special Issue, we are pleased to invite original manuscripts focusing on the relationships between nuclear receptors and human disorders, as well as novel drug innovation.

Prof. Dr. Akira Sugawara
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.