Translational and Molecular Research of Neurological Disorders

Dear Colleagues, 

The burden of neurodegenerative diseases cannot be understated; a larger aging population represents a challenge for health systems caring for patients with idiopathic diseases such as Alzheimer’s disease and Parkinson’s disease. The lack of disease-modifying therapies may mirror a limited understanding of those conditions’ underlying pathogenesis. That is also the case for genetic diseases associated with pathological nucleotide expansions such as frontotemporal dementia, Huntington’s disease, and other polyQ disorders. Basic science faces a challenge in questioning current models of putative pathogenesis, opening new paths, and translating advances in our understanding of disease mechanism. This issue is focused on basic science and translational studies that include in vitro and animal models of neurological disorders. Clinical contributions that include biomolecular experiments or genetic studies are also welcomed to be submitted.

Neurological disorders to be included in this issue are, among others:

• Alzheimer’s disease (AD);
• Amyotrophic lateral sclerosis (ALS);
• Frontotemporal dementia (FTD);
• Huntington disease and similar phenotypes (HD);
• Parkinson’s disease (PD);
• Spinocerebellar ataxias (SCAs).

Dr. José Miguel Laffita-Mesa
Dr. Martin Paucar
Prof. Dr. Per Svenningsson
Guest Editors

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