Molecular Insight into Skeletal Muscle Atrophy and Regeneration

Dear Colleagues,

Skeletal muscle wasting can be induced by chronic illnesses, aging, malnutrition, disease, and acute/chronic inflammatory conditions. Muscle atrophy leads to mobility, fragility, and a loss of independence, while also increasing the mortality and morbidity of the illness.

Muscle regeneration occurs after muscle injury, exercise, or physiological demands. Muscle regeneration involves inflammation, activation, proliferation, differentiation, and the maturation of satellite cells. Growth factors and mechanical stress from exercise play critical roles in promoting this process.

Therefore, understanding the processes of skeletal muscle wasting and regeneration offers insights for developing therapies to mitigate muscle loss and promote muscle recovery.

This Special Issue invites both original articles and reviews that can provide the readers of IJMS with novel research on the molecular mechanisms and possible treatments related to enhancing muscle regeneration and counteracting muscle wasting, such as growth factors, gene therapy, stem cell transplantation, exercise, and nutraceutical interventions.

Dr. Elena Nebot
Dr. Teresa Priego Cuadra
Dr. Ana Isabel Martín Velasco
Guest Editors

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