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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Aug 2026 | 1 articles | Viewed by 694 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Applications of PET/CT: Current Status and Future Perspectives

edited by Emmanouil Panagiotidis and

Jules T. Zhang-Yin

submission deadline 30 Aug 2026 | 1 articles | Viewed by 3297 | Submission Open

Keywords: PET/CT; diagnostic imaging; molecular imaging; oncology; PSMA; FAPI; SSTR; novel tracers; quantitative PET

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Advances in Cerebrovascular Disease: Clinical Diagnosis, Treatment, and Prognosis

edited by Federico Mazzacane

submission deadline 30 Aug 2026 | 1 articles | Viewed by 2753 | Submission Open

Keywords: cerebrovascular disease; ischemic stroke; intracerebral hemorrhage; neuroimaging; prognosis; biomarkers; precision medicine; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Integrating Health Informatics and Artificial Intelligence for Advanced Medicine

edited by

Joaquim Carreras

submission deadline 30 Aug 2026 | Viewed by 718 | Submission Open

Keywords: artificial intelligence; machine learning; artificial neural networks; prognosis; treatment; medicine; health care; pathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Brain/Neuroimaging 2025–2026

edited by Ronald Antulov

submission deadline 31 Aug 2026 | 15 articles | Viewed by 29638 | Submission Open

Keywords: advanced neuroimaging; dual-energy CT; photon-counting CT; perfusion MRI; MRI fingerprinting; brain lesions; neurodegenerative disorders; brain imaging; diagnosis; prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Vascular Diagnostic Imaging

edited by

Hyo-Suk Ahn

submission deadline 31 Aug 2026 | 5 articles | Viewed by 26990 | Submission Open

Keywords: flow-mediated dilation (FMD); optical coherence tomography (OCT); intravascular ultrasound (IVUS)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Game-Changing Concepts in Reproductive Health

edited by Mark I. Evans and Christian R. Macedonia

submission deadline 31 Aug 2026 | 8 articles | Viewed by 18378 | Submission Open

Keywords: pregnancy; artificial intelligence; prenatal diagnosis; genetic sequencing; diagnostic tests; screening tests; public policy; electronic fetal monitoring; introducing new technologies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Dental Diagnostics

edited by

Dirk Ziebolz

and Margherita Fontana

submission deadline 31 Aug 2026 | 11 articles | Viewed by 18085 | Submission Open

Keywords: diagnosis; diagnostic imaging; artificial intelligence; caries; periodontitis; stomatognathic diseases

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosing Respiratory Diseases and Impaired Gas Exchange Using Machine Learning

edited by

Robert LeMoyne

Jakub Rafl

and Martin Rozanek

submission deadline 31 Aug 2026 | 5 articles | Viewed by 16896 | Submission Open

Keywords: machine learning; user trust with machine learning; deep learning; blood gas sensors; oximeters; wearables; computer automated diagnosis of health status; respiratory diseases; impaired gas exchange; advanced diagnostics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Developments and Future Trends in Thoracic Imaging

edited by Ioana Andreea Gheonea

submission deadline 31 Aug 2026 | 8 articles | Viewed by 14622 | Submission Open

Keywords: X-ray; computed tomography; magnetic resonance imaging; ultra-low-dose CT; photon-counting CT; oncology; artificial intelligence; emergency radiology; thoracic trauma

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Dermatology

edited by Choon Chiat Oh

submission deadline 31 Aug 2026 | 6 articles | Viewed by 13848 | Submission Open

Keywords: dermatology; artificial intelligence; deep learning; skin cancers; diagnostic imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Insights into the Diagnosis and Prognosis of Eye Diseases

edited by

Rosa Giglio

and

Daniele Tognetto

submission deadline 31 Aug 2026 | 9 articles | Viewed by 12955 | Submission Open

Keywords: diagnosis; prognosis; eye diseases; markers; clinical practice and patient care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pathophysiologic Mechanisms, Diagnosis and Management of Venous Thromboembolism

edited by Emanuele Valeriani

submission deadline 31 Aug 2026 | 5 articles | Viewed by 12838 | Submission Open

Keywords: anticoagulants; deep vein thrombosis; diagnosis; pathophysiology; pulmonary embolism; venous thrombosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Dermatology and Venereology: Diagnosis and Management

edited by

Giulia Ciccarese

submission deadline 31 Aug 2026 | 4 articles | Viewed by 10878 | Submission Open

Keywords: skin infections; sexually transmitted infections; human papillomavirus; syphilis; pityriasis rosea; exanthem

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

AI and Digital Health for Disease Diagnosis and Monitoring, 2nd Edition

edited by AKM Azad, Mohammad Ali Moni and

Hussain Mohammed Dipu Kabir

submission deadline 31 Aug 2026 | 9 articles | Viewed by 10675 | Submission Open

Keywords: artificial intelligence; chronic disease; disease monitoring; disease prediction; machine learning; personalized treatment; health technology; big data analytics; public health; wearable health devices

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Application of Artificial Intelligence to Oral Diseases

edited by

Gang Li

submission deadline 31 Aug 2026 | 7 articles | Viewed by 10471 | Submission Open

Keywords: oral disease; artificial intelligence; AI-driven diagnosis; oral radiology; cone beam computed tomography (CBCT)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Metabolic Diseases: Diagnosis, Management, and Pathogenesis

edited by Dee Pei

submission deadline 31 Aug 2026 | 5 articles | Viewed by 10189 | Submission Open

Keywords: metabolic disease; obesity; aging; machine learning; pathophysiology; prevalence; ethnic differences

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Current Perspectives and Gaps in the Diagnosis and Management of Rheumatic Diseases

edited by Vikas Majithia

submission deadline 31 Aug 2026 | 4 articles | Viewed by 9359 | Submission Open

Keywords: rheumatology; rheumatic diseases; inflammatory connective tissue diseases; rheumatoid arthritis; systemic lupus erythematosus; vasculitis; spondyloarthritis; scleroderma; osteoarthritis; current perspective; diagnosis; treatment; management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Clinical Biochemistry, 2nd Edition

edited by Yu Chen

submission deadline 31 Aug 2026 | 3 articles | Viewed by 7264 | Submission Open

Keywords: clinical biochemistry; medical diagnosis; biomarkers; proteomic profiling; metabolomic profiling; high throughput technologies

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnostics and Therapeutic Explorations in Aging

edited by

Alvita Vilkevičiūtė

submission deadline 31 Aug 2026 | 3 articles | Viewed by 7107 | Submission Open

Keywords: molecular markers; genetics; epigenetics; biochemistry; biomarkers; telomeres; age-related disease; senescence; mitochondrial dysfunction; immunogenetics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Head and Neck and Oral Maxillofacial Radiology

edited by

Qiyong Hemis Ai

submission deadline 31 Aug 2026 | 6 articles | Viewed by 6397 | Submission Open

Keywords: medical imaging; head and neck; machine learning; radiomics analysis; medical image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Advances in Thoracic Surgery: Clinical Diagnosis, Treatment, and Prognosis—2nd Edition

edited by

Stefano Elia

submission deadline 31 Aug 2026 | 4 articles | Viewed by 6262 | Submission Open

Keywords: thoracic surgery; lung cancer; pleural diseases; mediastinal malignancies; surgical outcome

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management in Cardiac Intensive Care Medicine

edited by

Elad Asher

submission deadline 31 Aug 2026 | 3 articles | Viewed by 6016 | Submission Open

Keywords: cardiac intensive care; cardiogenic shock; acute heart failure; hemodynamic monitoring; mechanical circulatory support; post-cardiac arrest care; critical care cardiology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Diagnostic and Interventional Cardiology: Bridging Imaging, Physiology, and Therapy

edited by Samit Shah and

Natalija Odanovic

submission deadline 31 Aug 2026 | 5 articles | Viewed by 5308 | Submission Open

Keywords: EKG; CCTA; MRI; SPECT; PET; Echo; OCT; IVUS; QFR; angioIMR

(This special issue belongs to the Section Medical Imaging and Theranostics)

Deep Learning and Multimodal Large Language Models in Tumor/Cancer Diagnosis, Prediction and Prognosis

edited by

Steven L. Fernandes

submission deadline 31 Aug 2026 | 3 articles | Viewed by 5228 | Submission Open

Keywords: diagnosis; prognosis; tumor/cancer; deep learning; multimodal large language models

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Multimodal Imaging: Enhancing Precision Medicine Across Diverse Clinical Pathways

edited by

Mariano Scaglione

and Salvatore Masala

submission deadline 31 Aug 2026 | 4 articles | Viewed by 5166 | Submission Open

Keywords: CT; XR; CT US; MRI; functional MRI; PET; SPECT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Predictive Biomarkers in Oncology

edited by

Jun Zhang

submission deadline 31 Aug 2026 | 7 articles | Viewed by 4982 | Submission Open

Keywords: predictive biomarkers; precision oncology; liquid biopsy; treatment response; biomarker validation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Multidisciplinary Diagnostic Approaches to Infectious Pathologies in Surgical Specialties

edited by

Elena Adelina Toma

and

Octavian Enciu

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4312 | Submission Open

Keywords: surgical infections; diagnostic advancements; antimicrobial resistance; molecular diagnostics; radiological imaging; microbiological assays; AI-driven diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Eye Disease: Diagnosis, Management, and Prognosis—2nd Edition

edited by

Adam Wylęgała

submission deadline 31 Aug 2026 | 7 articles | Viewed by 4234 | Submission Open

Keywords: eye disease; diagnosis; prognosis; OCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Diagnostics in Head and Neck Oncology

edited by Xindong Fan, Siyi Li, Longwei Hu and

Yuchen Shen

submission deadline 31 Aug 2026 | 6 articles | Viewed by 4140 | Submission Open

Keywords: head and neck; tumor; surgical diagnosis; non-invasive diagnostic method; diagnostic biomarkers; intraoperative imaging; pathology; minimally invasive biopsy; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Imaging of Autoimmune Diseases

edited by Simone Appenzeller

submission deadline 31 Aug 2026 | 1 articles | Viewed by 4120 | Submission Open

Keywords: autoimmune diseases; systemic lupus erythematosus; systemic sclerosis; diagnosis; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Pediatric Diseases: 2nd Edition

edited by

Elena Tarca

submission deadline 31 Aug 2026 | 6 articles | Viewed by 4079 | Submission Open

Keywords: pediatrics; neonatal medicine; congenital malformations; pediatric orthopedics and trauma; pediatric oncology; pediatric surgery; pediatric urology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Diagnostic Approaches in Cardiovascular and Metabolic Disorders: From Pathophysiology to Clinical Practice

edited by

Iris Bararu-Bojan

and

Manuela Ciocoiu

submission deadline 31 Aug 2026 | 3 articles | Viewed by 3880 | Submission Open

Keywords: biomarkers; cardiovascular diseases; metabolic disorders; diagnostic imaging; precision medicine; pathophysiology; early diagnosis; risk stratification; omics technologies; clinical application

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Future of Cardiac Imaging in the Diagnosis, 2nd Edition

edited by

Grigorios Korosoglou

submission deadline 31 Aug 2026 | 2 articles | Viewed by 3857 | Submission Open

Keywords: cardiovascular imaging; diagnosis and management; early detection; risk stratification; emerging technologies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Contemporary Achievements in Diagnosis and Treatment of Gynecological and Obstetric Conditions

edited by

Radmila Sparić

submission deadline 31 Aug 2026 | 4 articles | Viewed by 3384 | Submission Open

Keywords: fibroid; endometriosis; pelvic pain; reproductive endocrinology; pregnancy complications; delivery; infertility; obstetrics; diagnosis; treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Challenges in Urology: From Diagnosis to Management—2nd Edition

edited by

and

submission deadline 31 Aug 2026 | 4 articles | Viewed by 3356 | Submission Open

Keywords: complications; rare; urologic cancer; urinary tract infections; urology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Trends in Mobility Medicine Diagnostics

edited by

Ugo Carraro

submission deadline 31 Aug 2026 | 1 articles | Viewed by 3119 | Submission Open

Keywords: mobility medicine; genetic and acquired neuromuscular disorders; mobility medicine of aging; mobility functional tests; skeletal muscle and cartilage imaging; quantitative tissue densitometry by 3D and 2D color CT and MRI; blood and mouth fluid biomarkers in mobility medicine; management and follow-up in mobility medicine; functional electrical stimulation of permanently denervated and reinnervating muscles

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Diagnosis and Management of Oral Cancer: Challenges, Advances, and Multidisciplinary Integration

edited by Eleni A. Georgakopoulou

submission deadline 31 Aug 2026 | 5 articles | Viewed by 2947 | Submission Open

Keywords: oral cancer; early diagnosis; oral squamous cell carcinoma; artificial intelligence; oral potentially malignant disorders; multidisciplinary management; tumor board; oral pathology; misinformation; dental screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Neurovascular Disease Imaging and Treatment

edited by Gabriel Broocks

submission deadline 31 Aug 2026 | 1 articles | Viewed by 2818 | Submission Open

Keywords: neurovascular imaging; ischemic stroke; endovascular therapy; CT/MR perfusion; vessel wall imaging; mechanical thrombectomy; cerebrovascular disease; neurointerventional radiology; stroke diagnostics; advanced image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Pathological Image Analysis, 3rd Edition

edited by

Masayuki Tsuneki

submission deadline 31 Aug 2026 | Viewed by 2794 | Submission Open

Keywords: deep learning; artificial intelligence; cancer; pathology; molecular pathology; histopathology; cytopathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

The Role of AI in Ultrasound, 2nd Edition

edited by

Hyuksool Kwon

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2672 | Submission Open

Keywords: artificial intelligence; medical ultrasound; diagnostic imaging; automated image interpretation; predictive modeling; personalized medicine; clinical workflow optimization; healthcare access; multidisciplinary innovation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Laboratory Diagnosis of Infections

edited by Mònica Balaguer Gargallo

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2473 | Submission Open

Keywords: infections; laboratory diagnosis; biochemical markers; bacterial resistance

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Electrocardiology: Diagnostic Innovations and Clinical Applications

edited by

Branislav Milovanovic

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2228 | Submission Open

Keywords: heart rate variability (HRV); deceleration capacity; acceleration capacity; late potentials; artificial intelligence; machine learning; autonomic nervous system; electrocardiographic biomarkers; risk stratification; predictive analytics; signal processing

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Cardiovascular and Vascular Imaging

edited by

Alfredo Mauriello

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2217 | Submission Open

Keywords: vascular disease; cardiovascular disease; POCUS; limb disease; vascular imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI and Computational Tools in Gastrointestinal Diagnostics: Shaping the Future of Clinical Practice

edited by

Chang Bang

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2106 | Submission Open

Keywords: artificial intelligence; machine learning; gastrointestinal endoscopy; computer-aided diagnosis (CAD); human-ai interaction; automation bias & neglect; digestive diseases; precision medicine; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Advances in Chest Imaging

edited by

Davide Colombi

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1968 | Submission Open

Keywords: chest imaging; lung cancer; interstitial lung diseases; machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Expanding Horizons: Optical Coherence Tomography in Cross-Specialty Diagnostic Practice

edited by

Nicusor Iftimia

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1968 | Submission Open

Keywords: optical coherence tomography; cross-specialty diagnosis; AI-assisted OCT; OCT angiography; multimodal imaging

(This special issue belongs to the Section Biomedical Optics)

Precision Diagnosis and Management of Breast Cancer

edited by

Kefah Mokbel

and Jajini Varghese

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1933 | Submission Open

Keywords: breast cancer; precision diagnostics; risk-adapted treatment; treatment de-escalation; surgery; radiotherapy; systemic therapy; liquid biopsy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Sports Injuries

edited by

Ki-Mo Jang

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1848 | Submission Open

Keywords: sports injury; sports medicine; diagnosis; treatment; surgery; rehabilitation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Trends and Diagnosis of Autoimmune Diseases

edited by

Abdulla Watad

and

Yonatan Shneor Patt

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1832 | Submission Open

Keywords: autoimmunity; diagnosis; biomarkers; comorbidities; epidemiology; metabolic syndrome; autoinflammatory conditions; psoriasis; cardiovascular disease

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

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