Imaging of Bone Metastases in Oncology

Dear Colleagues,

Bone metastases are well known complications to advanced cancer, e.g., in common cancers like prostate, breast, and lung cancer. Imaging of bone metastases are key in staging, suspected recurrent disease, and for treatment monitoring of palliative care in metastatic disease. Imaging modalities like bone scintigraphy, X-ray, and CT have standard of care in the last decades. Newer modalities like PET/CT with various tracers and diffusion-weighed MRI have been introduced with apparent premium diagnostic performance. Modern imaging modalities also offer opportunities for quantitative analysis of bone lesions with improved prognostic values. Improved detection rates raise the question of stage migration, e.g., how to define and treat oligometastatic disease. From a diagnostic test accuracy perspective, bone metastases may be difficult to handle for several reasons, including failure to obtain a valid reference for the presence or absence of maliognancy, in particular at the lesional level. This Special Issue provides an up to date view of the advances made towards imaging of bone metastases in oncology. It canvasses all fields and modalities of imaging of bone metastases, from diagnosis, prognosis, comparative studies with other biomarkers, research methodology, health care analyses, and guidelines.

Prof. Lars J. Petersen
Assoc. Prof. Helle D. Zacho
Guest Editors

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