Special Issue "Single Cell Analysis and Spatial Omics for Cell-Based Diagnostics"
Deadline for manuscript submissions: 28 February 2021.
Interests: spatial omics; single cell analysis; molecular imaging; high-dimensional pathology; cellular and subcellular networks in cancers, pediatric diseases, and infections; artificial intelligence in Image-based diagnostics, and personalized medicine
Powerful genome-wide technologies have expanded the field of genomics for finding gene regulatory factors. However, these approaches can only provide population average data that combine information from millions of cells. This population heterogeneity can be resolved by analyzing interactions of regulatory elements in single cells. Current single-cell profiling technologies resolve this cellular variability using label-free monitoring, live-cell imaging, microfluidics single-cell assays, and single-molecule nucleic acid detection methods to achieve spatially resolved analysis of genes, proteins, and metabolites. While single-cell methods shed light on cell-based diagnostics, they have been limited to the screening of only a few genes at a time. There is an increasing demand in biology and medicine for single-cell analysis technologies that can both capture spatial data and high-throughput molecular differences of individual cells. To provide solutions to this important need, this Special Issue discusses emerging technologies and computational approaches to define a new field of spatial omics (genomics, proteomics, metabolomics, and multi-omics) in health and disease.
Dr. Ahmet Coskun
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- single-cell sequencing
- molecular barcoding
- image bioinformatics
- cell-based assays