New Insights into Proteomics and Post-translational Modification of Proteins

Dear Colleagues,

Proteins are fundamental biological molecules in cells, while post-translational modifications (PTMs) are key mechanisms to dynamically and reversibly regulate the functions of proteins. Systematic and large-scale analysis of protein sequences, structures, variations, expression profiles, PTMs and functional impacts not only enables a much better understanding of life, but also provides high-potential biomarkers and drug targets for biomedical consideration. Recently, advances in cutting-edge technologies, such as high-throughput mass spectrometry, high-content imaging or screening analysis, and protein microarray on the experimental side, as well as artificial intelligence (AI), statistical methods, network modeling, and proteogenomic integration on the computational side, have generated new insights in proteomics and PTMs of proteins and held the concept of proteomics-driven precision medicine (PDPM).

The purpose of this Special Issue is to highlight recent technological innovations in the analysis of proteomics and PTMs of proteins, as well as new biological findings using these new techniques. The topics include but are not limited to high-throughput experimental technology, AI/statistics/network technology, proteomics-oriented findings, and comprehensive data resources on proteins, proteomics and/or PTMs. Interdisciplinary studies are highly encouraged and appreciated. We welcome the submission of both original research articles and reviews.

Prof. Dr. Yu Xue
Guest Editor

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