Cellular and Molecular Mechanisms of Tumor Biology
This special issue belongs to the section "Cellular Pathology".
Special Issue Information
Dear Colleagues,
When normal cells are transformed into tumors, they acquire the ability to proliferate uncontrollably, invade surrounding tissues, and metastasize to distant organs while avoiding immune surveillance. Cellular and molecular dysregulations play instructive roles in this process.
The scope of this Special Issue includes the following:
- Cellular context of tumor origin;
- Genetic and epigenetic alterations;
- Clonal selection and tumor stem cells;
- Tumor metabolism;
- Invasion and metastasis;
- Tumor microenvironment and immune evasion;
- Phenotypic plasticity and therapeutic resistance.
Tumor biology is an evolutionary process driven by genetic mutations, epigenetic alterations, deregulated signaling pathways, metabolic reprogramming, and immune escape, all of which arise from the cellular context of origin. Understanding cellular and molecular mechanisms governing tumor biology is essential to discover novel and effective therapies.
Dr. Liang Lei
Guest Editor
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Keywords
- tumorigenesis
- signaling pathways
- tumor immune responses
- tumor microenvironment
- tumor metabolism
- tumor therapy
- tumor stem cells
- invasion and metastasis
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Published Papers
Cells - ISSN 2073-4409