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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (2nd Edition)

edited by

Tianhong Li

submission deadline 15 Feb 2026 | Viewed by 195 | Submission Open

Keywords: precision oncology; lung cancer; oncogenic target; targeted therapy; biomarker; diagnosis

(This special issue belongs to the Section Molecular Cancer Biology)

Epigenetics and Non-Coding RNAs in Multiple Myeloma

edited by

Rui Bergantim

submission deadline 15 Feb 2026 | Viewed by 136 | Submission Open

Keywords: multiple myeloma; epigenetics; non-coding RNAs; microRNAs (miRNAs); long non-coding RNAs (lncRNAs); circular RNAs (circRNAs); DNA methylation; histone modifications; drug resistance; precision medicine

(This special issue belongs to the Section Cancer Biomarkers)

Genetic Changes in CNS Neoplasms

edited by Kimberly Bojanowski Hoang

submission deadline 15 Feb 2026 | Viewed by 96 | Submission Open

Keywords: primary brain tumor; secondary brain tumor; metastasis; glioma; genetics; genomics; CNS; neoplasms

(This special issue belongs to the Section Cancer Biomarkers)

Prognostic and Predictive Biomarkers in Ovarian Cancer

edited by Jayakumar Nair

submission deadline 15 Feb 2026 | Viewed by 32 | Submission Open

Keywords: molecular biomarkers; clinical biomarkers; immune biomarkers; genetic biomarkers; ovarian cancer; personalized medicine

(This special issue belongs to the Section Cancer Biomarkers)

Diagnosis, Treatment and Prevention of Gastrointestinal Cancer (2nd Edition)

edited by

Anna Kakehashi

and Min Gi

submission deadline 18 Feb 2026 | 2 articles | Viewed by 9501 | Submission Open

Keywords: cancer; screening; diagnosis; anti-cancer; drugs; mechanisms of carcinogenesis; chemopreventive agents

(This special issue belongs to the Section Cancer Therapy)

Gaps in Cancer Cachexia Research

edited by Jose M. Garcia and

Lindsey J. Anderson

submission deadline 20 Feb 2026 | 3 articles | Viewed by 10849 | Submission Open

Keywords: cancer cachexia; physical function; innovative models; rehabilitation; patient-reported outcomes; gender; aging; skeletal muscle; brain; adipose tissue

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Epigenetic Regulation in Cancers

edited by

Sudhir Rai

and

Seema Kumari

submission deadline 20 Feb 2026 | 3 articles | Viewed by 10636 | Submission Open

Keywords: oncogenes; tumor suppressor genes; tumor microenvironment; cancer therapy; DNA and histone methylation; microRNAs; epitranscriptomics; RNA modifications; modifying proteins

(This special issue belongs to the Section Tumor Microenvironment)

Quality of Life and Side Effects Management in Cancer Treatment (3rd Edition)

edited by

António Araújo

submission deadline 20 Feb 2026 | 4 articles | Viewed by 8263 | Submission Open

Keywords: cancer treatment adverse events; quality of life in cancer patients; chemotherapy adverse events; target therapy adverse events; immunotherapy adverse events; hormonotherapy adverse events; chemotherapy-induced nausea and vomiting; cancer pain

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Chronic Intestinal Inflammation and Cancers (2nd Edition)

edited by Livia Biancone and David Laharie

submission deadline 20 Feb 2026 | 3 articles | Viewed by 5134 | Submission Open

Keywords: colorectal cancer; chronic inflammation; inflammatory bowel disease; inflammation-associated dysplasia; outcomes; cancer molecular pathways

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Ultrasonography for Pancreatobiliary Cancer

edited by

Yasunobu Yamashita

submission deadline 20 Feb 2026 | 3 articles | Viewed by 5062 | Submission Open

Keywords: endoscopic ultrasonography; abdominal ultrasonography; early diagnosis project; screening; EUS-FNA; interventional EUS; enhancement EUS; EUS-RFA

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Multiple Myeloma: Recent Advances in Diagnosis, Analysis and Therapeutic Management: 2nd Edition

edited by

Juan Manuel Rosa-Rosa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3064 | Submission Open

Keywords: multiple myeloma (MM); hematologic malignancies; next-generation sequencing; heterogeneous disease; tumor heterogeneity; genomic landscape; outcomes; novel treatments; clinical trial

(This special issue belongs to the Section Cancer Therapy)

Breast Cancer Biomarkers and Clinical Translation: 2nd Edition

edited by

Cristian Scatena

and Carmine De Angelis

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2042 | Submission Open

Keywords: breast cancer diagnosis; cancer risk; cell reprogramming; biomarkers; resistance; precision therapy

(This special issue belongs to the Section Cancer Biomarkers)

Advanced Surgical Modalities in Breast Cancer Treatment

edited by Jan Žatecký

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1168 | Submission Open

Keywords: breast cancer surgery; breast cancer localization; breast conserving surgery; mastectomy; oncoplastic surgery; axillary lymph node staging; sentinel lymph node biopsy; targeted axillary dissection

(This special issue belongs to the Section Clinical Research of Cancer)

Fibroblasts as Playmakers of Cancer Progression: Current Knowledge and Future Perspectives (2nd Edition)

edited by

Kenichiro Ishii

submission deadline 20 Feb 2026 | Viewed by 268 | Submission Open

Keywords: tumor microenvironment; reactive stroma; fibroblasts; cancer progression; heterotypic interactions between cancer cells and fibroblasts; reactive stroma-targeted therapy

(This special issue belongs to the Section Molecular Cancer Biology)

AI-Driven Predictive Modeling in Radiation Therapy: Toward Precision and Personalized Clinical Applications

edited by

Yujie Huang

submission deadline 20 Feb 2026 | Viewed by 244 | Submission Open

Keywords: AI-based radiotherapy; predictive modeling in oncology; personalized radiation therapy; radiomics and dosiomics; adaptive radiotherapy; treatment outcome prediction; explainable AI in medicine; multimodal data integration; clinical decision support systems; precision cancer treatment

Molecular Tumor Boards: Promise and Limitations for Personalized Cancer Therapy: 2nd Edition

edited by

Claudia Paret

submission deadline 20 Feb 2026 | Viewed by 203 | Submission Open

Keywords: targeted therapy; drug repositioning; biomarkers; basket trials; precision oncology; personalized medicine

(This special issue belongs to the Section Molecular Cancer Biology)

Cancer and Aging: Challenges in Geriatric Cancer Survivorship

edited by

Ruth Parks

and Dana E. Giza

submission deadline 20 Feb 2026 | Viewed by 76 | Submission Open

Keywords: geriatric oncology; survivorship; advance care planning; quality of life; de-escalation of treatment

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Minimal Residual Disease in Solid Tumors: Emerging Technologies and Clinical Applications

edited by

Sofia Agelaki

Kleita Michaelidou

and Aristeidis Boukouris

submission deadline 25 Feb 2026 | Viewed by 191 | Submission Open

Keywords: minimal residual disease (MRD); solid tumors; circulating tumor DNA (ctDNA); liquid biopsy; tumor-informed assays; precision oncology

(This special issue belongs to the Section Cancer Biomarkers)

Radiation Therapy for Modern Management of Bone Metastases (2nd Edition)

edited by

Francesco Cellini

submission deadline 25 Feb 2026 | Viewed by 179 | Submission Open

Keywords: radiotherapy; palliative care; steretactic radiotherapy; SBRT; immunotherapy; chemotherapy; oligometastases

(This special issue belongs to the Section Cancer Therapy)

Harnessing the Gut Microbiome to Improve Colorectal Cancer Outcomes

edited by Carole S. Richard

submission deadline 25 Feb 2026 | Viewed by 138 | Submission Open

Keywords: colorectal cancer (CRC); gut microbiome; screening; CRC cells; the gut microenvironment; oncological outcomes

(This special issue belongs to the Section Infectious Agents and Cancer)

Understanding HTLV-1 Induced Cancer: From Molecular Pathways to Treatment Strategies

edited by

George Eric Blair

and Suchitra Mohanty

submission deadline 25 Feb 2026 | Viewed by 94 | Submission Open

Keywords: HTLV-1; adult T-cell leukemia/lymphoma (ATLL); tax protein; HBZ protein; epigenetic regulation; immune evasion; chronic inflammation; host– pathogen interactions; viral oncogenesis; translational research

(This special issue belongs to the Section Infectious Agents and Cancer)

Advances in the Treatment of Gastrointestinal (GI) Cancers

edited by

Yoshiyasu Kono

submission deadline 27 Feb 2026 | 1 articles | Viewed by 1177 | Submission Open

Keywords: gastrointestinal cancers; targeted therapy; immunotherapy; precision oncology; biomarkers; molecular mechanisms; tumor microenvironment; resistance to therapy; translational research; clinical trials

(This special issue belongs to the Section Cancer Therapy)

Clinical and Translational Updates in Renal Cell Carcinoma (2nd Edition)

edited by

Irbaz B Riaz

submission deadline 27 Feb 2026 | Viewed by 131 | Submission Open

Keywords: renal cell carcinoma; RCC; machine cearning; clinical; translational developments

(This special issue belongs to the Section Clinical Research of Cancer)

Application of Imaging in Breast Cancer

edited by

Yun-Chung Cheung

Yao Melissa Min-Szu

and Chung Wai-Shan

submission deadline 28 Feb 2026 | 6 articles | Viewed by 18318 | Submission Open

Keywords: breast cancer; mammography/tomosynthesis/contrast-enhanced mammography; sonography/contrast-enhanced sonography; magnetic resonance imaging; PET/CT; quantitative imaging; elastography; optical imaging; artificial intelligence; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Challenges and Opportunities for Novel Therapeutic Strategies in Pediatric Oncology

edited by

Jeong A Park

and

Jaume Mora

submission deadline 28 Feb 2026 | 7 articles | Viewed by 15936 | Submission Open

Keywords: antibody-drug conjugate; bispecific antibody; cancer predisposition; CAR T cell; immunotherapy; leukemia; monoclonal antibody; neuroblastoma; pediatric cancer; photoimmunotherapy; precision medicine; sarcoma; translational research; tyrosine kinase inhibitor

(This special issue belongs to the Section Cancer Therapy)

Advances in Bladder Preservation Approaches for Bladder Cancer (2nd Edition)

edited by

Jay J. Liao

and Todd A. Yezefski

submission deadline 28 Feb 2026 | 5 articles | Viewed by 13030 | Submission Open

Keywords: bladder cancer; bladder preservation; trimodality therapy; chemoradiation; immunotherapy; intravesical therapy; BCG refractory or unresponsive

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

State of the Art and Novelties in Multidisciplinary Approach to Soft Tissue and Bone Sarcomas

edited by Ron Batash, Alberto Crimì, Moshe Schaffer and

Pietro Ruggieri

submission deadline 28 Feb 2026 | 6 articles | Viewed by 11833 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; treatment; diagnosis; radiation therapy; chemotherapy

(This special issue belongs to the Section Cancer Therapy)

Advances in Oncological Imaging (2nd Edition)

edited by

Michaela Cellina

and

Maurizio Cè

submission deadline 28 Feb 2026 | 5 articles | Viewed by 9110 | Submission Open

Keywords: oncological imaging; radiomics; deep learning; machine learning; image reconstruction; artificial intelligence; outcome prediction; oncological treatment planning; advanced imaging; personalized medicine

(This special issue belongs to the Section Methods and Technologies Development)

Improving Surgical Care for Patients with Hepatobiliary and Pancreatic Cancers

edited by Christopher B. Nahm and Kai M. Brown

submission deadline 28 Feb 2026 | 2 articles | Viewed by 7751 | Submission Open

Keywords: hepatobiliary; pancreatic; surgery; biomarkers; prognosis; treatment strategy

(This special issue belongs to the Section Cancer Therapy)

Navigating the Landscape of Female Cancers: Recent Discoveries and Treatment Trends

edited by

Federica Martorana

and Giacomo Barchiesi

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7725 | Submission Open

Keywords: female malignancies; breast cancer; gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer

(This special issue belongs to the Section Cancer Therapy)

New Insights into General, Functional and Oncologic Urology

edited by Kajetan Juszczak and

Przemysław Adamczyk

submission deadline 28 Feb 2026 | 4 articles | Viewed by 7237 | Submission Open

Keywords: basic science; experimental models; urological cancer; management innovations; multidisciplinary approaches; treatment outcomes

(This special issue belongs to the Section Clinical Research of Cancer)

Regulators of Breast Cancer Metastasis

edited by

Terumi Kohwi-Shigematsu

and

Saori Furuta

submission deadline 28 Feb 2026 | 2 articles | Viewed by 6728 | Submission Open

Keywords: tumor progression regulators; metastasis; tumor microenvironment; biomarkers for recurrence; transcriptional regulation; chromatin structure; epigenetics; cancer metabolism; cancer immunity; microbiome

(This special issue belongs to the Section Cancer Metastasis)

Cervical Cancer: Clinical Feature, Trial and Management

edited by

Roberto Tozzi

Marco Noventa

and Carlo Saccardi

submission deadline 28 Feb 2026 | 2 articles | Viewed by 5699 | Submission Open

Keywords: cervical cancer; diagnosis; minimally invasive surgery; laparoscopy; locally advanced disease; management; treatment; adjuvant chemotherapy; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Diagnosis, Staging, and Management for Gynecologic Oncology

edited by

Malgorzata Klimek

submission deadline 28 Feb 2026 | 1 articles | Viewed by 5460 | Submission Open

Keywords: gynecologic oncology; cancer biology; HPV infection; molecular risk factors; translational medicine; cancer staging systems; radiation therapy; brachytherapy; radioresistance

(This special issue belongs to the Section Cancer Therapy)

Personalized Radiotherapy in Cancer Care (2nd Edition)

edited by

Bin S. Teh

and

Waqar M. Haque

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5259 | Submission Open

Keywords: predictive biomarkers; treatment-related toxicity; radiation treatments; radiation dose and volume; personalized radiation therapy

(This special issue belongs to the Section Methods and Technologies Development)

3D Cultures and Organoids in Cancer Research

edited by

Karla Rubio

and

César López-Camarillo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 5090 | Submission Open

Keywords: 3D cell cultures; organotypic 3D cultures; 3D spheroids models; induced pluripotent stem (iPS); organoids; tumoroids

(This special issue belongs to the Section Molecular Cancer Biology)

Exploring Non-Coding RNA Signatures in Cancer: Definitions and Implications for Diagnosis and Therapy

edited by

Amog Urs

and Udhayakumar Gopal

submission deadline 28 Feb 2026 | 5 articles | Viewed by 4821 | Submission Open

Keywords: non-coding RNA; biomarkers; gene regulation; microRNA; long non-coding RNA; circular RNA; therapeutic targets

(This special issue belongs to the Section Cancer Therapy)

Perioperative Care in Gynecologic Oncology: 2nd Edition

edited by Nikolaos Thomakos and

Vasilios Pergialiotis

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3889 | Submission Open

Keywords: enhanced recovery; ERAS; immunonutrition; prehabilitation; gynecologic oncology; minimally invasive surgery

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Immunoediting in Cancer Therapies

edited by

Vijay Kumar

submission deadline 28 Feb 2026 | 1 articles | Viewed by 3004 | Submission Open

Keywords: cancer; cancer immunology; immunosurveillance; immunoediting; immunotherapy; immunomodulation; immunometabolism

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Cell Therapy in Hematological Malignancies

edited by

Francesco Gaudio

and

Stefano Martinotti

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2372 | Submission Open

Keywords: cell therapy; immunotherapy; target therapy; hematological malignancies; tumor immunology

(This special issue belongs to the Section Cancer Therapy)

Heterogeneity in Intra-Cranial Tumors: Diagnostic, Prognostic, and Therapeutic Implications

edited by

Francois Ducray

, Shawn L. Hervey-Jumper and Thiebaud Picart

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2366 | Submission Open

Keywords: glioma; histo-molecular classification; intra-tumoral heterogeneity; inter-tumoral heterogeneity; meningioma; neuro-oncology; neurosurgery

(This special issue belongs to the Section Cancer Metastasis)

Innovative and Personalized Approaches to Improve Patient Outcomes in Gynecological Oncology

edited by Anke Smits and James Dilley

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2261 | Submission Open

Keywords: gynecological cancer; lifestyle; prehabilitation; rehabilitation; survival; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Advancements in Technologies for Radiation Biology, Oncology, and Protection

edited by

Zhixiang Wang

and

Yi Wang

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2080 | Submission Open

Keywords: radiation biology; oncology; radiation protection; carcinogenesis; multi-omics; radiomics; radiotherapy; biodosimetry; adverse outcome pathway (AOP); personalized medicine

(This special issue belongs to the Section Cancer Informatics and Big Data)

Chronic Lymphocytic Leukemia: From Genetics to Therapy

edited by

Javier Loscertales-Pueyo

submission deadline 28 Feb 2026 | 3 articles | Viewed by 1962 | Submission Open

Keywords: chronic lymphocytic; leukemia treatment; biology

(This special issue belongs to the Section Cancer Therapy)

Predictive and Prognostic Biomarkers for Response to Neoadjuvant Chemotherapy for Breast Cancer

edited by Tarek M. A. Abdel-Fatah

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1500 | Submission Open

Keywords: breast cancer; predictive and prognostic biomarkers; neoadjuvant chemotherapy; HER2-targeting agents; complete pathological response

(This special issue belongs to the Section Cancer Therapy)

MRI and Artificial Intelligence in Oncology: Current Research and Future Directions

edited by

Amita Shukla-Dave

and

Ramesh Paudyal

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1461 | Submission Open

Keywords: MRI; AI; radiology; oncology; clinical trials

(This special issue belongs to the Section Methods and Technologies Development)

Advances in the Diagnosis and Treatment of Genitourinary Cancers (2nd Edition)

edited by Piotr Radziszewski and

Łukasz Zapała

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1386 | Submission Open

Keywords: genitourinary cancer; point-of-care diagnostics; personalized treatment; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Clinical Research and Prognosis of HER2-Positive Breast Cancer

edited by

Pierfranco Conte

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1306 | Submission Open

Keywords: HER2-positive breast cancer; targeted therapy; anti-HER2 therapy; long-term impacts; prognostic

(This special issue belongs to the Section Clinical Research of Cancer)

Evolution of Cancer Therapies: Access of Developing Countries to Modern Oncology

edited by

Salem Chouaib

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1162 | Submission Open

Keywords: conventional cancer therapies; modern oncology; recission medicine; cancer immunotherapy; artificial intelligence; targeted agents; equity and globally equal access

(This special issue belongs to the Section Cancer Therapy)

Novel Approaches to Machine Learning and Artificial Intelligence in Cancer Research and Care (2nd Edition)

edited by

Caroline Chung

and Chris J. Gibbons

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1104 | Submission Open

Keywords: machine learning; deep learning; artificial intelligence; interpretable AI; data quality; metadata; data quality; cancer; MLOps; data science; real-world data

(This special issue belongs to the Section Cancer Informatics and Big Data)

Displaying special issue 351-400 on page 8 of 24.

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