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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Study on Clinical Treatment of Brain Tumors
edited by Shinya Watanabe
submission deadline 9 Sep 2026 | 3 articles | Viewed by 9946 | Submission Open
Keywords: brain tumors; clinical treatment; anti-tumor drugs; clinical trials
(This special issue belongs to the Section Cancer Therapy)
Quality of Life and Side Effects Management in Cancer Treatment (3rd Edition)
edited by
submission deadline 10 Sep 2026 | 9 articles | Viewed by 18874 | Submission Open
Keywords: cancer treatment adverse events; quality of life in cancer patients; chemotherapy adverse events; target therapy adverse events; immunotherapy adverse events; hormonotherapy adverse events; chemotherapy-induced nausea and vomiting; cancer pain
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Exercise and Cancer Treatment: The Clinical Application of Exercise Oncology
edited by and Geovana Leite
submission deadline 10 Sep 2026 | 4 articles | Viewed by 5555 | Submission Open
Keywords: exercise oncology; cancer therapy; immunotherapy; patient outcomes
(This special issue belongs to the Section Clinical Research in Cancer)
Advances in Interventional Oncologic Therapies
edited by Edward W. Lee and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 16399 | Submission Open
(This special issue belongs to the Section Cancer Therapy)
Advances in Artificial Intelligence Methodologies and Applications in Cancer
edited by Jennifer G. Le-Rademacher and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 8742 | Submission Open
Keywords: artificial intelligence (AI); AI tools; cancer research; diagnostic tools; medical imaging; biomarkers; ethical considerations; patient care
(This special issue belongs to the Section Methods and Technologies Development)
First-Line Therapy in Thoracic Oncology
edited by Antonio D'Andrilli and
submission deadline 15 Sep 2026 | 5 articles | Viewed by 8114 | Submission Open
Keywords: thoracic oncology; lung cancer; thymoma; mediastinal tumors
(This special issue belongs to the Section Cancer Therapy)
Robot-Assisted Surgery for Urologic Cancer
edited by Gabriele Sorce, Francesco Pellegrino and Ettore Di Trapani
submission deadline 15 Sep 2026 | 3 articles | Viewed by 7316 | Submission Open
Keywords: robot-assisted surgery; urologic oncology; minimally invasive surgery; prostate cancer surgery; kidney cancer surgery; bladder cancer surgery; robotic platforms; robotic surgery training
(This special issue belongs to the Section Cancer Therapy)
Radiotherapy for Sarcoma
edited by Safia K. Ahmed and Miranda Lam
submission deadline 15 Sep 2026 | 3 articles | Viewed by 5547 | Submission Open
Keywords: soft tissue sarcoma; bone sarcoma; advanced sarcoma; radiation therapy; particle therapy; multidisciplinary sarcoma care
(This special issue belongs to the Section Cancer Therapy)
Endometrial Cancer Therapy: Foundations and Future Directions submission deadline 15 Sep 2026 | 4 articles | Viewed by 4273 | Submission Open
Keywords: pathology; surgery; radiotherapy; chemotherapy; new agents; immunotherapy; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Breast Cancer: Immune Response, Immune Microenvironment, and Immunotherapy submission deadline 15 Sep 2026 | 2 articles | Viewed by 2615 | Submission Open
Keywords: breast cancer; immune response; tumor immune microenvironment; immunotherapy resistance; intrinsic and extrinsic mechanisms; immune checkpoint inhibitors; T-cell dysfunction; cytokines; cancer vaccines; tumor immunosuppression
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Childhood Acute Lymphoblastic Leukemia
edited by Noriko Satake
submission deadline 15 Sep 2026 | 2 articles | Viewed by 1817 | Submission Open
Keywords: childhood acute lymphoblastic leukemia; diagnosis; novel agents; targeted therapy; personalized medicine
(This special issue belongs to the Section Pediatric Oncology)
Evidence-Based Care for Managing Oncologic Emergencies in Patients with Cancer submission deadline 15 Sep 2026 | 1 articles | Viewed by 1542 | Submission Open
Keywords: oncologic emergencies; cancer; urgent; infections; adverse events; thrombosis; febrile neutropenia; pain; spinal cord compression; goals of care
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advances in Endoscopy for Early Detection and Precision Diagnosis of Gastrointestinal Cancers
edited by Ishaan Vohra
submission deadline 15 Sep 2026 | 1 articles | Viewed by 1366 | Submission Open
Keywords: endoscopy; gastrointestinal cancer; early detection; artificial intelligence; advanced imaging; molecular diagnostics; precision medicine; biomarkers; screening; surveillance
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
New Models of Cancer Care to Improve Patient Experiences and Clinical Outcomes
edited by
submission deadline 15 Sep 2026 | 1 articles | Viewed by 1226 | Submission Open
Keywords: patient-centered care; community-based interventions; innovative care models; digital health solutions; patient engagement; clinical outcomes; value-based cancer care
Hepatocellular Carcinoma: Risk Factors, Diagnosis and Treatments submission deadline 15 Sep 2026 | Viewed by 269 | Submission Open
Keywords: chronic hepatitis; cirrhosis; viral hepatitis; HCC; MASLD; imaging; TACE; radio-ablation; chemotherapy
Aptamers Against Cancer submission deadline 15 Sep 2026 | Viewed by 255 | Submission Open
Keywords: aptamers; cancer theranostics; targeted therapy; biosensors; molecular imaging
(This special issue belongs to the Section Methods and Technologies Development)
Onco-Nephrology: From Molecular to Clinical Studies submission deadline 16 Sep 2026 | 1 articles | Viewed by 2505 | Submission Open
Keywords: acute kidney injury in oncology; chronic kidney disease and cancer; paraneoplastic glomerulonephritis; immunotherapy-related nephrotoxicity; tumor lysis syndrome; nephrotoxicity of chemotherapeutic agents; DNA damage; epigenetic modifications; molecular pathways in cancer-associated kidney injury; biomarkers for early detection of kidney injury
(This special issue belongs to the Section Clinical Research in Cancer)
Advances and Innovations in Cancer Drug Therapeutics
edited by
submission deadline 17 Sep 2026 | Viewed by 247 | Submission Open
Keywords: cancer; drug discovery; targeted drugs; computer-aided drug discovery; formulation advances; immunotherapy; transcriptomics; proteomics; metabolomics
(This special issue belongs to the Section Cancer Drug Development)
Artificial Intelligence in Ocular Oncology
edited by
submission deadline 18 Sep 2026 | 3 articles | Viewed by 2934 | Submission Open
Keywords: ocular tumor; eye cancer; artificial intelligence; ophthalmology
(This special issue belongs to the Section Methods and Technologies Development)
Management of Pancreatic Cancer: 2nd Edition
edited by
submission deadline 18 Sep 2026 | 2 articles | Viewed by 930 | Submission Open
Keywords: pancreatic cancer; adenocarcinoma; neuroendocrine carcinomas; molecular and pathological aspects; diagnosis; medical treatment; palliative therapy
Advances in Salivary Gland Carcinoma: 2nd Edition
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 12485 | Submission Open
Keywords: salivary gland tumors; head and neck cancer; facial nerve preservation; facial nerve reconstruction; facial nerve sacrifice; parotid cancer; parotidectomy; prognostic factors
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Clinical Outcomes in Upper GI Cancers
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 3340 | Submission Open
Keywords: esophageal cancer; gastric cancer; esophagogastric junction cancer; surgery; endoscopy; chemotherapy; immuno-therapy; molecural target therapy; biomarker
(This special issue belongs to the Section Clinical Research in Cancer)
Development of Hepatitis C Virus-Related Cancers
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 1051 | Submission Open
Keywords: hepatitis C virus (HCV); hepatocellular carcinoma (HCC); extrahepatic malignancies; lymphoproliferative disorders; viral oncogenesis; chronic inflammation and cancer; direct-acting antivirals (DAAs); cancer surveillance in HCV patients
(This special issue belongs to the Section Clinical Research in Cancer)
Molecular Pathology Insights in Thyroid Cancer
edited by Salma Khan
submission deadline 20 Sep 2026 | Viewed by 538 | Submission Open
Keywords: non-coding RNAs; epigenetics; biomarkers; BRAF mutations; RAS mutations; targeted therapy; precision medicine; genomic profiling; tumor heterogeneity; therapeutic resistance
(This special issue belongs to the Section Cancer Pathophysiology)
Advances in Targeting Drug-Resistant Tumors: Approaches Mitigating Inflammation and Oxidative Stress Pathways submission deadline 20 Sep 2026 | Viewed by 222 | Submission Open
Keywords: inflammation; oxidative stress; reactive oxygen species; Nrf2; NFkB; HPGD; drug resistance
(This special issue belongs to the Section Cancer Drug Development)
Study on Surgical Treatment of Ovarian Cancer
edited by
submission deadline 25 Sep 2026 | 3 articles | Viewed by 1804 | Submission Open
Keywords: ovarian cancer; surgical treatment; ovarian cancer prevention
(This special issue belongs to the Section Cancer Therapy)
Combination Immunotherapy for Cancer Treatment—2nd Edition submission deadline 25 Sep 2026 | 1 articles | Viewed by 1484 | Submission Open
Keywords: immunotherapy; immune checkpoint inhibitor; cancer vaccine; novel cancer therapy; treatment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Targeting the Vulnerabilities of Oncogene Activation (Second Edition)
edited by
submission deadline 25 Sep 2026 | Viewed by 545 | Submission Open
Keywords: tumorigenesis; tumor-suppressor genes; oncogene; target
(This special issue belongs to the Section Methods and Technologies Development)
Acute Myeloid Leukemia: Updates on Diagnosis and Novel Management Strategies
edited by Ana Vidović
submission deadline 25 Sep 2026 | Viewed by 368 | Submission Open
Keywords: acute myeloblastic leukemia; diagnosis; prognosis; intensive chemotherapy; target therapy; allogeneic stem cell transplantation
(This special issue belongs to the Section Clinical Research in Cancer)
Role of Iron Metabolism in Tumor Progression
edited by
submission deadline 25 Sep 2026 | Viewed by 362 | Submission Open
Keywords: iron metabolism; ferroptosis; tumor microenvironment; oxidative stress; iron chelation therapy; ferritin; transferrin receptor; cancer metabolism; redox homeostasis; therapeutic targeting
(This special issue belongs to the Section Molecular Cancer Biology)
Clinical Pathology in Cancer: From Diagnosis to Precision Medicine
edited by
submission deadline 28 Sep 2026 | Viewed by 515 | Submission Open
Keywords: cancer biomarkers; precision medicine; histopathology; clinical pathology; diagnosis; prognostic/predictive biomarker
(This special issue belongs to the Section Cancer Pathophysiology)
Advances and Challenges in the Diagnosis and Treatment of Urological Malignancies (2nd Edition) submission deadline 30 Sep 2026 | 10 articles | Viewed by 22123 | Submission Open
Keywords: prostate cancer; bladder cancer; upper urinary tract tumors; kidney cancer; testicular tumors; molecular markers; lymph node metastasis; diagnosis; radical treatment; systemic treatment
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Soft Tissue and Bone Sarcoma (2nd Edition) submission deadline 30 Sep 2026 | 13 articles | Viewed by 18058 | Submission Open
Keywords: bone sarcoma; soft tissue sarcoma; prognosis; diagnosis; detection; molecular biomarkers; histopathology; treatment
(This special issue belongs to the Section Cancer Therapy)
Immunotherapy for Skin Cancers
edited by and Lara Valeska Maul-Duwendag
submission deadline 30 Sep 2026 | 4 articles | Viewed by 12628 | Submission Open
Keywords: melanoma; non-melanoma skin cancer; merkel cell carcinoma; kaposi sarcoma; cutaneous angi-osarcoma; immune checkpoint; immunotherapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Decision-Making Biomarkers in the Treatment of Hepatocellular Carcinoma
edited by and
submission deadline 30 Sep 2026 | 5 articles | Viewed by 11744 | Submission Open
Keywords: hepatocellular carcinoma; borderline resectable; conversion therapy; neoadjuvant therapy; immunotherapy; immune-related adverse event; molecular-targeted agent
(This special issue belongs to the Section Cancer Biomarkers)
Health Economic and Policy Issues Regarding Cancer
edited by
submission deadline 30 Sep 2026 | 4 articles | Viewed by 9247 | Submission Open
Keywords: cancer economics; health policy; cost-effectiveness; financial toxicity; healthcare disparities; value-based oncology
Neurosurgery Research on Brain Tumors: A Focus on Gliomas and Other Intra-Axial Brain Tumors
edited by , Carlo Giussani, Cesare Zoia and Daniele Bongetta
submission deadline 30 Sep 2026 | 2 articles | Viewed by 8079 | Submission Open
Keywords: neurosurgery; glioma; neuropsychology; neurophysiological monitoring; intraoperative imaging (including iMRI and iOUS); neuroanatomy; outcome; prognosis and quality of life; MRI (including fMRI, MR spectroscopy, perfusion and DTI tractography); radiogenomics; multimodal treatments; druggable targets; artificial intelligence and deep learning
(This special issue belongs to the Section Clinical Research in Cancer)
Cellular and Molecular Mechanisms of Malignant Nervous System Cancers
edited by
submission deadline 30 Sep 2026 | 7 articles | Viewed by 7753 | Submission Open
Keywords: medulloblastoma; pediatric glioma; neuroblastoma; diagnosis and prognostic markers; IDH, TERT, and EGFR mutations; DNA methylation; treatment approaches and strategies (chemotherapy, radiation therapy, immunotherapy, and targeted therapy); resistance mechanisms; tumor microenvironment; molecular characteristics of tumor heterogeneity
(This special issue belongs to the Section Molecular Cancer Biology)
Current Issues, Innovations, and Emerging Therapies in Thoracic Surgical Oncology
edited by Inderpal S. Sarkaria and Shamus Carr
submission deadline 30 Sep 2026 | 5 articles | Viewed by 6854 | Submission Open
Keywords: non-small cell lung cancer; esophageal cancer; thymic epithelial tumors; BAP1 malignant mesothelioma; robotic surgery; immunotherapy; cellular therapies; molecular imaging
The EGFR-Tyrosine Kinase Inhibitors (EGFR-TKIs) and Immune Checkpoint Inhibitors (ICIs) for Non-Small Cell Lung Cancer submission deadline 30 Sep 2026 | 2 articles | Viewed by 6819 | Submission Open
Keywords: non-small cell lung cancer; target therapy; EGFR-tyrosine kinase inhibitors; immunotherapy; immune checkpoint inhibitors; molecular analysis; surgery; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Biomarkers for Therapy Response in Gastrointestinal Malignancies: Predicting Outcomes and Personalizing Care submission deadline 30 Sep 2026 | 5 articles | Viewed by 6782 | Submission Open
Keywords: immunotherapy; biomarkers; resistance mechanisms; predictive markers; clinical trials; translational research
(This special issue belongs to the Section Cancer Biomarkers)
Fertility Preservation and Hormonal Health in Oncology submission deadline 30 Sep 2026 | 4 articles | Viewed by 6714 | Submission Open
Keywords: oncofertility; fertility preservation; hormonal health; cancer survivorship; reproductive oncology
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Novel Perspectives in Hepato-Biliary and Pancreatic Cancer
edited by Tudor Mocan and Emil-Ioan Moiș
submission deadline 30 Sep 2026 | 4 articles | Viewed by 6625 | Submission Open
Keywords: HCC; cholangiocarcinoma; surgery; biliary drainage; pancreatic cancer; combination therapies
(This special issue belongs to the Section Cancer Therapy)
Multiple Myeloma: Diagnosis and Therapy submission deadline 30 Sep 2026 | 3 articles | Viewed by 6395 | Submission Open
Keywords: multiple myeloma; plasma cell disorders; relapsed and refractory multiple myeloma; blood and marrow transplant
(This special issue belongs to the Section Cancer Therapy)
Proteomic and Oncogenic Biomarkers in Gastrointestinal Cancer submission deadline 30 Sep 2026 | 4 articles | Viewed by 5897 | Submission Open
Keywords: tumor biomarkers; early detection; tumor progression; carcinogenesis; inflammatory mediators; gastrointestinal cancer; prognostic biomarkers
(This special issue belongs to the Section Cancer Biomarkers)
Exercise Interventions for People Living with Cancer: Advances in Knowledge and Implementation
edited by and Chris Swain
submission deadline 30 Sep 2026 | 3 articles | Viewed by 5844 | Submission Open
Keywords: cancer; survivorship; exercise; physical activity; implementation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Contemporary Lung Cancer Nodal Staging and Evolving Therapeutic Paradigms submission deadline 30 Sep 2026 | 8 articles | Viewed by 5741 | Submission Open
Keywords: ninth TNM classification; nodal staging; endoscopic/endobronchial ultrasound; neoadjuvant/adjuvant therapy; biomarker testing
(This special issue belongs to the Section Cancer Therapy)
Biomarkers of Urological Cancers
edited by , and Zisis Kratiras
submission deadline 30 Sep 2026 | 6 articles | Viewed by 5741 | Submission Open
Keywords: biomarkers; urothelial cancer; prostate cancer; renal cancer; checkpoint inhibitors; PD-L1; KIM-1; FGFR3; BRCA; HRD
(This special issue belongs to the Section Cancer Biomarkers)
State-of-the-Art Research on Multiple Myeloma Progression: 2nd Edition
edited by
submission deadline 30 Sep 2026 | 3 articles | Viewed by 5515 | Submission Open
Keywords: multiple myeloma; novel targets; novel therapies; molecular therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Advances in Lung Cancer Treatment Strategies submission deadline 30 Sep 2026 | 4 articles | Viewed by 5447 | Submission Open
Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors; chemoimmunotherapy; target therapy; biomarkers; non-small cell lung cancer; precision medicine
(This special issue belongs to the Section Cancer Therapy)
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