Advances in Endoscopy for Early Detection and Precision Diagnosis of Gastrointestinal Cancers

Dear Colleagues,

Gastrointestinal cancers remain among the leading causes of cancer-related mortality worldwide, with early detection being crucial for improving patient outcomes. Recent technological advances in endoscopic imaging, artificial intelligence integration, and molecular diagnostics are revolutionizing our approach to early cancer detection and precision diagnosis. This Special Issue aims to showcase cutting-edge research and clinical innovations in endoscopic techniques that enhance the identification and characterization of precancerous lesions and early-stage gastrointestinal malignancies.

We invite original research articles, systematic reviews, and meta-analyses exploring novel endoscopic modalities including advanced imaging techniques (narrow-band imaging, confocal laser endomicroscopy, optical coherence tomography), AI-assisted detection systems, molecular and biomarker-based diagnostics, and therapeutic endoscopic interventions. This Special Issue welcomes contributions examining clinical outcomes, diagnostic accuracy, cost-effectiveness analyses, and translational research bridging basic science discoveries with clinical applications in esophageal, gastric, pancreaticobiliary, and colorectal cancers.

We look forward to receiving your contributions advancing the field of endoscopic early cancer detection and precision diagnosis.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

• Advanced endoscopic imaging modalities (NBI, AFI, BLI, LCI, chromoendoscopy)
• Artificial intelligence and machine learning in endoscopic diagnosis
• Confocal laser endomicroscopy and optical coherence tomography
• Molecular and biomarker-based endoscopic diagnostics
• Endoscopic ultrasound for staging and tissue acquisition
• Quality metrics and standardization in endoscopic cancer detection
• Cost-effectiveness of screening and surveillance programs
• Therapeutic endoscopic interventions (EMR, ESD, ablation techniques)

Dr. Ishaan Vohra
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.