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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Updates on Urologic Oncology: From Diagnosis to Localized and Systemic Therapy Options (2nd Edition)

edited by

Giuseppe Palermo

submission deadline 30 Jun 2026 | 4 articles | Viewed by 10007 | Submission Open

Keywords: bladder cancer; prostate cancer; renal cancer; urologic cancer treatment; urologic cancer diagnosis; urologic cancer innovation; urologic neoplasm therapy; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Clinical Diagnosis, Treatment, and Prognosis of Uveal Melanoma

edited by Josep Maria Caminal Mitjana

submission deadline 30 Jun 2026 | 5 articles | Viewed by 10002 | Submission Open

Keywords: uveal melanoma; choroidal melanoma; gene expression profiling; immunotherapy; metastasis; radiotherapy; liquid biopsy; circulating tumor cells; brachytherapy; next-generation sequencing; proton therapy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Gastrointestinal Cancer Surgery

edited by Florian Primavesi and

Daniel Neureiter

submission deadline 30 Jun 2026 | 6 articles | Viewed by 9395 | Submission Open

Keywords: gastrointestinal cancer surgery; precision surgery; personalized medicine; robotics; pathology; colorectal cancer; stomach cancer; pancreatic cancer; hepatocellular cancer; biliary tract cancer

(This special issue belongs to the Section Cancer Therapy)

News and How Much to Improve in Management of Soft Tissue Sarcomas

edited by Vicente Artigas-Raventós and

José Manuel Asencio

submission deadline 30 Jun 2026 | 5 articles | Viewed by 8525 | Submission Open

Keywords: soft tissue sarcomas; prevalent types; multidisciplinary board; reference centers; news diagnosis methods and treatments; implication of IA and 3D in sarcomas; implication of minimally aggressive surgical techniques

(This special issue belongs to the Section Cancer Therapy)

The Progress of Pancreatectomy for Pancreatic Cancer Treatment

edited by

Reinhold Függer

and

Matthias Biebl

submission deadline 30 Jun 2026 | 4 articles | Viewed by 8076 | Submission Open

Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatectomy timing in multimodal regimen; minimally invasive pancreatectomy for PDAC; pancreatectomy and resectability; extended pancreatectomy; vascular resection and reconstruction; outcome research— pancreatectomy for cancer in unselected patient cohorts; interaction of postoperative complications and preoperative or adjuvant therapy; postoperative pancreatic fistula

(This special issue belongs to the Section Clinical Research of Cancer)

Human Papillomavirus (HPV) and Related Cancer

edited by

Beata Biesaga

submission deadline 30 Jun 2026 | 3 articles | Viewed by 7720 | Submission Open

Keywords: HPV; carcinogenesis; methods of virus identification diagnostics; prognostification

(This special issue belongs to the Section Infectious Agents and Cancer)

The Role of Neutrophils in Tumor Progression and Metastasis

edited by

Rakesh K. Singh

and Leah M. Cook

submission deadline 30 Jun 2026 | 4 articles | Viewed by 7445 | Submission Open

Keywords: neutrophils; innate immunity; tumor; microenvironment; metastasis; targeted therapeutics

(This special issue belongs to the Section Cancer Metastasis)

Epigenetic Regulation in Hematologic Malignancies

edited by Travis S. Johnson

submission deadline 30 Jun 2026 | 3 articles | Viewed by 7132 | Submission Open

Keywords: epigenetic regulation; hematologic malignancies; DNA methylation; non-coding RNA; therapeutic targeting

(This special issue belongs to the Section Tumor Microenvironment)

Advances in Abdominal Surgical Oncology and Intraperitoneal Therapies

edited by

Juan Jose Segura-Sampedro

and

Constantino Fondevila

submission deadline 30 Jun 2026 | 5 articles | Viewed by 6976 | Submission Open

Keywords: abdominal oncologic surgery; minimally invasive techniques; laparoscopy; robotics; fluorescence; artificial intelligence; augmented vision; peritoneal carcinomatosis; intraperitoneal chemotherapy; liquid biopsy

(This special issue belongs to the Section Cancer Therapy)

Exploring Immunotherapy in Colorectal Cancer

edited by

Alessandro Passardi

Luca Esposito

and

Chiara Gallio

submission deadline 30 Jun 2026 | 1 articles | Viewed by 4820 | Submission Open

Keywords: colorectal cancer; immunotherapy; immune checkpoint inhibitors; mismatch repair; microsatellite instability; biomarkers

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Applications of Ex Vivo Microscopy in Cancer Detection and Diagnosis

edited by J. Quincy Brown

submission deadline 30 Jun 2026 | 3 articles | Viewed by 4320 | Submission Open

Keywords: microscopy; cancer; optical sectioning; diagnosis; detection

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Cancer Data and Statistics: 2nd Edition

edited by

Vesna Zadnik

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3668 | Submission Open

Keywords: cancer registries; cancer incidence; cancer survival; population-based studies; cancer risk factors

(This special issue belongs to the Section Cancer Informatics and Big Data)

Integrating Precision Medicine with Nanotechnology to Overcome Drug Resistance in Cancer

edited by Yan Li

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3205 | Submission Open

Keywords: precision medicine; nanotechnology; drug resistance

(This special issue belongs to the Section Methods and Technologies Development)

Advances in PET/CT for Predicting Cancer Outcomes

edited by Ahmad Shariftabrizi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3095 | Submission Open

Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism

(This special issue belongs to the Section Methods and Technologies Development)

Neuroscience of Brain Tumors

edited by Zefferino Rossini,

Miguel Segura Ginard

and Maria Pia Tropeano

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3072 | Submission Open

Keywords: neurosurgery; neuroscience; brain tumors (gliomas; meningiomas; and pituitary tumors); neural pathway; neuroimaging; neurogenetics

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical Applications of Precision Diagnosis for Thyroid Cancers and Its Clinical Use for Treatments Choice

edited by

Maria Trovato

, Silvia Martina Ferrari and

Fausto Famà

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2804 | Submission Open

Keywords: thyroid cancer; precision diagnosis; clinical management; molecular tests; molecular therapeutic targets; thyroid cancer epidemiology; artificial intelligence; health inequalities

(This special issue belongs to the Section Clinical Research of Cancer)

Chemoprevention Advances in Cancer (2nd Edition)

edited by

Komal Raina

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2697 | Submission Open

Keywords: cancer prevention; chemoprevention; nutrition and cancer; bio-active food components; natural products; non-toxic anticancer agents; precision nutrition in cancer; tumor metabolomics; gut microbiome in cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Classification, Risk Assessment and Clinical Management of Malignant Thyroid Nodules: 2nd Edition

edited by Claudio Spinelli and Marco Ghionzoli

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2438 | Submission Open

Keywords: thyroid nodule; thyroid cancer; guidelines; surgery

(This special issue belongs to the Section Clinical Research of Cancer)

New Strategies for the Treatment of Melanoma and Non-Melanoma Skin Cancer

edited by

Yoshihide Asano

and

Taku Fujimura

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2420 | Submission Open

Keywords: melanoma; non-melanoma skin cancer; immunotherapy; anti-PD-1 antibody; BRAF/MEK inhibitors; racial differences; prognosis

(This special issue belongs to the Section Cancer Therapy)

Feature Review Papers on Cancer Epidemiology, Disparities, and Prevention

edited by Adam Barsouk

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2367 | Submission Open

Keywords: epidemiology; disparities; oncology; cancer; prevention

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Neurofibromatosis

edited by Yunjia Chen and Yulong Fu

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1779 | Submission Open

Keywords: neurofibromatosis; schwannomatosis; NF1; NF2; SMARCB1; LZTR1

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical Pathology of Lung Cancer (2nd Edition)

edited by

Letizia Gnetti

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1644 | Submission Open

Keywords: lung cancer; pathology; diagnosis; treatment; targeted therapies; immunotherapy

(This special issue belongs to the Section Clinical Research of Cancer)

Plasma and Cancer Treatment

edited by

Michael Keidar

and

Vikas Soni

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1597 | Submission Open

Keywords: cold atmospheric plasma (CAP); cancer treatment; plasma medicine; reactive oxygen species (ROS); apoptosis; tumor; non-thermal plasma; plasma oncology; cancer and molecular biology; clinical translation; in vivo/preclinical

(This special issue belongs to the Section Cancer Therapy)

Unveiling the Complexity of Hepato-Biliary-Pancreatic Cancers: From Pathogenesis to Management

edited by

Stefano Cacciatore

and Luiz Zerbini

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1304 | Submission Open

Keywords: hepatocellular carcinoma (HCC); cholangiocarcinoma; pancreatic ductal adenocarcinoma (PDAC); tumour microenvironment; molecular biomarkers; therapeutic resistance; cancer immunotherapy; early cancer detection; precision oncology; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Neurofibromatosis Type 1 (NF1) Related Tumors (2nd Edition)

edited by

Daochun Sun

and

Sameer Farouk Sait

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1138 | Submission Open

Keywords: NF1; tumorigenesis; cancer stem cells; targeted therapy; tumor microenvironment; epigenetics; case report; metastasis; clinical trials

(This special issue belongs to the Section Tumor Microenvironment)

Urological Cancer: Epidemiology and Genetics

edited by Ilir Agalliu and Evan Kovac

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1102 | Submission Open

Keywords: environmental factors; lifestyle; genetic susceptibility; biomarkers; prostate cancer; bladder cancer; kidney cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Targeted Radiotracers for Molecular Imaging and Therapy in Cancer

edited by

Vladimir Tolmachev

and

Maryam Oroujeni

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1024 | Submission Open

Keywords: theranostic; radionuclide molecular imaging; targeted therapy; specificity; selectivity; personalized medicine; radiopharmaceuticals

(This special issue belongs to the Section Methods and Technologies Development)

Genetic Alterations and Features in the Development of Gastrointestinal Cancer

edited by

Alexandra Voutsina

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1008 | Submission Open

Keywords: gastrointestinal cancers; genetic alteration; epigenetic regulation; the mechanism of tumorigenesis; precision treatment

(This special issue belongs to the Section Molecular Cancer Biology)

PARP Inhibitors in Cancer Therapy

edited by

Jie Jiang

and

Fu Gui

submission deadline 30 Jun 2026 | 1 articles | Viewed by 949 | Submission Open

Keywords: PARP inhibitors; cancer therapy; DNA damage repair; drug discovery

(This special issue belongs to the Section Cancer Therapy)

Recent Advances in Epidemiology of Childhood Cancer

edited by Rafael Peris-Bonet,

Rebeca Ramis

and Adela Cañete

submission deadline 30 Jun 2026 | 1 articles | Viewed by 815 | Submission Open

Keywords: childhood cancer epidemiology; childhood cancer registries; environmental causes of childhood cancer; genetic epidemiology; molecular epidemiology; survival of children with cancer; quality of life; social determinants and inequalities; information technologies and statistical innovations

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Soft Tissue Sarcomas—New Diagnostic and Therapeutic Perspectives Through Clinical Genomic Profiling

edited by

Ewa Koscielniak

and

Monika Sparber-Sauer

submission deadline 30 Jun 2026 | 1 articles | Viewed by 671 | Submission Open

Keywords: soft tissue sarcoma; molecular profiling; cancer genomics; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Pleural Mesothelioma: From Diagnosis to Treatment

edited by

Giovanni Luca Ceresoli

and

Paolo Andrea Zucali

submission deadline 30 Jun 2026 | 1 articles | Viewed by 567 | Submission Open

Keywords: pleural mesothelioma; histological classification; molecular characteristics; immunotherapy; chemotherapy; radiotherapy; surgery; targeted therapy; emerging therapies

(This special issue belongs to the Section Cancer Therapy)

Advances in Radiology for the Detection, Diagnosis, and Management of Breast Cancer

edited by Takouhie Catherine Maldjian and Mary M. Salvatore

submission deadline 30 Jun 2026 | 1 articles | Viewed by 521 | Submission Open

Keywords: breast cancer; radiology; breast imaging; mammography; MRI; ultrasound; AI; radiomics; diagnosis; treatment response; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Radiation Therapy in Oncology

edited by Jerzy Wydmański

submission deadline 30 Jun 2026 | 1 articles | Viewed by 443 | Submission Open

Keywords: radiotherapy; radiation injury; systemic therapy; immunotherapy; cancer; concurrent chemoradiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Understanding the Molecular Basis and Immunobiology of Renal Cell Carcinoma and Exploring Novel Therapeutic Strategies

edited by

Heba Khella

submission deadline 30 Jun 2026 | Viewed by 428 | Submission Open

Keywords: renal cell carcinoma; molecular basis; immunobiology; tumor microenvironment; immunotherapy; targeted therapy; metastasis; precision medicine; biomarkers; non-coding RNA; miRNA; prognosis; molecular diagnostics; translational research

(This special issue belongs to the Section Cancer Therapy)

Surgical Perspectives in Lung Cancer: From Technique to Outcome

edited by Takahiro Homma and Hyun Koo Kim

submission deadline 30 Jun 2026 | Viewed by 397 | Submission Open

Keywords: minimally invasive surgery; enhanced recovery after surgery (ERAS); uniportal VATS; robotic-assisted thoracic surgery (RATS); surgical education; perioperative management; energy devices; lung cancer surgery

(This special issue belongs to the Section Cancer Therapy)

Recent Updates on Treatment of Uveal Melanoma

edited by Richard D. Carvajal, Shaheer Khan and Brian Peter Marr

submission deadline 30 Jun 2026 | Viewed by 392 | Submission Open

Keywords: uveal melanoma; systemic therapies; surgical innovations; radiotherapy; genetic and molecular insights; translational research

(This special issue belongs to the Section Cancer Therapy)

Contemporary Management for Gallbladder Cancer: From Diagnosis to Treatment (2nd Edition)

edited by Hiromichi Ito

submission deadline 30 Jun 2026 | Viewed by 373 | Submission Open

Keywords: gallbladder cancer; radical cholecystectomy; adjuvant chemotherapy; neoadjuvant therapy; incidental gallbladder cancer; multidisciplinary management; preoperative staging

(This special issue belongs to the Section Cancer Therapy)

Innovative Treatments Based on Genomic Aberrations in Leukemia and Lymphoma

edited by

Vera Ulrike Bacher

and

Ashwini K. Yenamandra

submission deadline 30 Jun 2026 | Viewed by 348 | Submission Open

Keywords: leukemia; lymphoma; AI and predictive modeling; MRD; B-ALL; DLBCL; genomics; treatment

(This special issue belongs to the Section Cancer Therapy)

Advanced Segmentation in Multimodal Nuclear Imaging of Solid Tumors and Lymphomas: Tools, Challenges, and Clinical Integration

edited by

Ken Kudura

and Robert Förster

submission deadline 30 Jun 2026 | 1 articles | Viewed by 335 | Submission Open

Keywords: multimodal nuclear imaging; artificial intelligence in nuclear medicine; radiomics in nuclear medicine; tumor segmentation; segmentation techniques; segmentation tools; outcome prediction; radioligand therapy

(This special issue belongs to the Section Methods and Technologies Development)

Cancer Inhibitory Receptors: Targeting Tumor Microenvironment Therapeutically

edited by

Vaishali Aggarwal

and Alok Kumar

submission deadline 30 Jun 2026 | Viewed by 322 | Submission Open

Keywords: immune checkpoint inhibitors; immunotherapy; tumor microenvironment; inhibitory receptors; immune system; T cells; malignant cells; therapeutic targets

(This special issue belongs to the Section Cancer Therapy)

Role of BCL-2 Family Proteins in Cancer: Therapeutic Advancements and Challenges

edited by Sajid Khan

submission deadline 30 Jun 2026 | Viewed by 304 | Submission Open

Keywords: BCL-2 family proteins; apoptosis; BH3 mimetics; thrombocytopenia; proteolysis-targeting chimeras; drug resistance; combination therapy; targeted drug delivery

(This special issue belongs to the Section Cancer Therapy)

Proton and Light Ion Therapy for Cancer

edited by Oliver Jäkel

submission deadline 30 Jun 2026 | Viewed by 293 | Submission Open

Keywords: novel beam delivery concepts; image guidance; adaptive therapy; in vivo monitoring; radiobiological studies with protons and light ions; clinical studies; outcome reports

(This special issue belongs to the Section Cancer Therapy)

Signaling Networks Controlling Ovarian Cancer Progression and Response to Therapy

edited by

Luca Tamagnone

and Roberta Mastrantonio

submission deadline 30 Jun 2026 | Viewed by 285 | Submission Open

Keywords: ovarian cancer; patient-derived models; mesothelium; ascites; immunotherapy; chemotherapy; drug resistance; metastasis; peritoneum; p53; BRCA; signaling pathway; metabolism

(This special issue belongs to the Section Tumor Microenvironment)

Advances in Neoadjuvant Therapy for Urologic Cancer

edited by Carlo Messina

submission deadline 30 Jun 2026 | Viewed by 271 | Submission Open

Keywords: neoadjuvant treatment; bladder cancer; prostate cancer; renal cell carcinoma; penile cancers; immunotherapy; antibody– drug conjugates

(This special issue belongs to the Section Cancer Therapy)

Cancer Disparities and Health Equity: Challenges, Insights, and Transformative Strategies

edited by

Mandi Pratt-Chapman

and Jane Ussher

submission deadline 30 Jun 2026 | Viewed by 224 | Submission Open

Keywords: scientific censorship; terminated grants; identity politics and health; LGBTQI+ cancer health equity; LGBTQI+ cancer survivorship and care

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Circadian Rhythms, Cancers and Chronotherapy (2nd Edition)

edited by

Francis Levi

Pasquale F. Innominato

and Esra Tasali

submission deadline 30 Jun 2026 | Viewed by 190 | Submission Open

Keywords: drug development and chronotherapy; chemotherapy; immunotherapy; targeted agents; radiotherapy; surgery; circadian host or tumor biomarkers; electronic patient-reported outcomes; circadian rhythms and sleep; sex- and age specificities; clinical trial designs; mathematical models and artificial intelligence; digital healthcare; telemedicine and logistics

(This special issue belongs to the Section Cancer Therapy)

The Extracellular Matrix and Tissue Engineering: Roles in the Tumor Microenvironment and Implications for Cancer Treatment

edited by

Maria Georgiadou

Eirini Velliou

and

Eugenia Roupakia

submission deadline 30 Jun 2026 | Viewed by 187 | Submission Open

Keywords: extracellular matrix remodeling; stiffness; cancer progression; tumor metastasis; tissue engineering; 3D models; anti-cancer therapies

(This special issue belongs to the Section Cancer Therapy)

Advances in Pancreatic Cancer: Exploring Biomarkers and Prognostic Predictors

edited by

Makoto Abue

submission deadline 30 Jun 2026 | Viewed by 151 | Submission Open

Keywords: pancreatic cancer; biomarkers; diagnosis; prognosis; liquid biopsy; proteomics; metabolomics; tumor microenvironment; genetic aberrations/mutations; inflammatory markers

(This special issue belongs to the Section Cancer Biomarkers)

Hepatocellular Carcinoma: Clinical Evidence and Emerging Therapeutic Benefits

edited by

Alessandro Loglio

submission deadline 30 Jun 2026 | Viewed by 144 | Submission Open

Keywords: artificial intelligence; downstaging; immunotherapy; multidisciplinary approaches; risk factors; nutrition

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 801-850 on page 17 of 24.

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