Advances in Bone Metastasis Research: From Mechanisms to Therapy
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Metastasis".
Deadline for manuscript submissions: 25 September 2026 | Viewed by 1117
Special Issue Editor
Special Issue Information
Dear Colleagues,
Bone is a predominant site of metastasis for prostate, breast, and lung, and melanoma cancers. Metastatic spread to the skeleton leads to severe complications, including pain, fractures, and spinal cord compression, which drastically diminish patient quality of life and survival.
This Special Issue addresses the pressing challenge of preventing and treating bone metastasis by showcaing the latest advancements in the field. We examine the "vicious cycle" of metastasis, with a focus on the molecular mechanisms underlying tumor cell homing, dormancy, and bone lesion formation.
The scope encompasses the bone metastatic niche, tumor–stroma interactions, and key molecular drivers. In parallel, the clinical dimension covers novel imaging, predictive biomarkers, therapeutic interventions, and the management of skeletal-related events. Through this integrated biological and clinical perspective, the Issue aims to provide a comprehensive platform to advance progress against bone-metastatic disease.
This Special Issue welcomes reviews as well as original research articles, which should be submitted by 25 September 2026.
Dr. Ye Lin
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bone metastasis
- tumour microenvironment
- biomarker
- targeted therapy
- detection
- palliative care
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