Boron Neutron Capture Therapy (BNCT) for Solid Cancers: (1) Preclinical Innovations and Biological Mechanisms
A Special Issue of Cancers (ISSN 2072-6694) belonging to the section "Methods and Technologies Development".
Deadline for manuscript submissions: 28 February 2027 | Viewed by 91
Editors
Interests: medical science; radiation therapy; dose analysis; refractory cancer;
Special Issues, Collections and Topics in MDPI journals
Interests: medical science; radiation therapy; dose analysis; refractory cancer;
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The BNCT is a form of tumor-cell targeted treatment in the field of radiation therapy and is essentially the “Cell-by-Cel Surgery”. This is made possible by a technology that selectively delivers large amounts of the boron isotope B-10 to tumor cells, irradiates them with a high dose of neutrons to trigger the boron neutron capture reaction (BNCR), and uses the immense energy particles released by that reaction to selectively destroy the tumor cells. Although this concept was proposed in the early 20th century, shortly after the discovery of neutrons, the technologies required to deliver large quantities of the boron agent to targeted tumor cells and to generate large quantities of neutrons using accelerators presented extreme difficulties; it is only recently that progress has finally begun to materialize. This Special Issue (1) provides an overview of the present preclinical studies on BNCT.
Dr. Yasuaki Ichikawa
Dr. Tadashi Hanafusa
Guest Editors
Manuscript Submission Information
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Keywords
- boron neutron capture therapy (BNCT)
- refractory cancer
- targeted therapy
- good patient QOL
- preclinical research
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