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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Early Diagnosis and Treatment of Gastric Cancer (2nd Edition)
edited by Sharona B. Ross
submission deadline 31 Aug 2026 | Viewed by 326 | Submission Open
Keywords: gastric cancer; tumor resection; liver tumors
(This special issue belongs to the Section Cancer Therapy)
The Invasion and Metastasis in Skin Cancer
edited by Emanuela Passoni, and
submission deadline 31 Aug 2026 | Viewed by 288 | Submission Open
Keywords: melanoma; skin cancer; basal cell carcinoma; squamous cell carcinoma; Kaposi’s sarcoma; dermoscopy; photoprotection; skin cancer prevention
Cancer Survivorship: Transforming Challenges into Quality Living
edited by and Tania Estapé
submission deadline 31 Aug 2026 | Viewed by 285 | Submission Open
Keywords: cancer survivorship; psychological adjustment; emotional well-being; coping; quality of life; family relationships; couple functioning; sexuality; return to work; psychosocial interventions; financial toxicity
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
The Role of Artificial Intelligence in Detection and Treatment of Head and Neck Cancer
edited by
submission deadline 31 Aug 2026 | Viewed by 281 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; large language models; multimodal integration; computer vision; pathomics; image-derived biomarkers
(This special issue belongs to the Section Methods and Technologies Development)
Epigenetic Markers of Cancer Diseases
edited by and Jessica Puzzuoli
submission deadline 31 Aug 2026 | Viewed by 278 | Submission Open
Keywords: epigenetics; DNA methylation; histone modifications; tumor suppressor genes; oncogenes; cancer biomarkers; early detection; disease progression; epigenetic therapy; DNA methyltransferase inhibitors; histone deacetylase inhibitors; liquid biopsy; cancer risk assessment; clinical translation
(This special issue belongs to the Section Molecular Cancer Biology)
Wnt Signaling Pathway in Cancer Immunotherapy
edited by and
submission deadline 31 Aug 2026 | Viewed by 277 | Submission Open
Keywords: Wnt signaling; immunotherapy; immune cells; macrophages; T-cell; CART cells; stromal cells; tumor microenvireonment; cancers; cancer stem cells
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Paradigm Shifts in Gynaecological Oncology Surgery (2nd Edition)
edited by
submission deadline 31 Aug 2026 | Viewed by 260 | Submission Open
Keywords: gynecological surgery; genomic risk management; survivorship health economics
(This special issue belongs to the Section Cancer Therapy)
Progress in Minimally Invasive Approaches in Gastrointestinal Cancer
edited by Florin Grama and
submission deadline 31 Aug 2026 | Viewed by 258 | Submission Open
Keywords: minimally invasive surgery; gastrointestinal cancer; endoscopic techniques; hybrid techniques
(This special issue belongs to the Section Methods and Technologies Development)
Pancreatic Cancer: Clinical Trials, Treatment Strategies, and Future Directions
edited by Brent Taiting Xia
submission deadline 31 Aug 2026 | Viewed by 254 | Submission Open
Keywords: pancreatic cancer; neoadjuvant therapy; clinical trials; pancreatectomy; chemoradiation
(This special issue belongs to the Section Clinical Research in Cancer)
Palliative and Supportive Care in Oncology
edited by and Heidrun Golla
submission deadline 31 Aug 2026 | Viewed by 253 | Submission Open
Keywords: screening; timely palliative care; caregivers; symptom control; digitalization; care structures; gender-specific aspects
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Artificial Intelligence in Gastrointestinal Cancer Diagnosis and Treatment
edited by Eun Jeong Gong
submission deadline 31 Aug 2026 | Viewed by 252 | Submission Open
Keywords: artificial intelligence; gastrointestinal cancer; deep learning; precision oncology; clinical decision support; large language model; explainable artificial intelligence
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Drug Delivery for Cancer Therapy (2nd Edition) submission deadline 31 Aug 2026 | Viewed by 250 | Submission Open
Keywords: cancer; oncology; therapeutic target; drug resistance; immunotherapy; chemotherapy; small molecule inhibitors; drug delivery; nanoparticle
(This special issue belongs to the Section Cancer Drug Development)
Head and Neck Cancer Surgery: Resection and Reconstruction
edited by , Kiyoto Shiga and Hisakazu Kato
submission deadline 31 Aug 2026 | Viewed by 237 | Submission Open
Keywords: head and neck cancer surgery; tumor resection; reconstructive surgery; microvascular free flap; functional reconstruction; oncologic outcomes; perioperative management; rehabilitation (speech and swallowing); imaging and surgical planning; multidisciplinary care
(This special issue belongs to the Section Methods and Technologies Development)
Emerging Therapies in the Management of Gastrointestinal Malignancies (3rd Edition) submission deadline 31 Aug 2026 | Viewed by 235 | Submission Open
Keywords: hepatocellular carcinoma; colorectal cancer; esophageal cancer; immunotherapy; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
Diagnosis and Novel Therapies for Pediatric Solid Tumor
edited by and
submission deadline 31 Aug 2026 | Viewed by 222 | Submission Open
Keywords: pediatric solid tumors; diagnosis; targeted therapy; immunotherapy; sequencing
(This special issue belongs to the Section Pediatric Oncology)
Advances in Brachytherapy in the Treatment of Tumors (2nd Edition)
edited by
submission deadline 31 Aug 2026 | Viewed by 220 | Submission Open
Keywords: brachytherapy; LDR; HDR; PDR; cervical cancer; prostate cancer; breast cancer
(This special issue belongs to the Section Cancer Therapy)
Oncological Outcomes of Active Surveillance Versus Radical Treatment in Localized Prostate Cancer
edited by
submission deadline 31 Aug 2026 | Viewed by 214 | Submission Open
Keywords: active surveillance; molecular markers; multiparametric magnetic resonance imaging; prostate cancer
Applications of Computed Tomography in Lung Cancer
edited by Yukinori Sakao
submission deadline 31 Aug 2026 | Viewed by 205 | Submission Open
Keywords: lung cancer; computed tomography (CT); radiomics; artificial intelligence (AI); image-guided surgery
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Laryngeal Cancer: Integrating Clinical Practice, Artificial Intelligence, Molecular Mechanisms, and Functional Rehabilitation
edited by Shuihong Zhou
submission deadline 31 Aug 2026 | Viewed by 204 | Submission Open
Keywords: laryngeal cancer; laryngeal carcinoma; head and neck cancer; artificial intelligence; radiomics; digital pathology; optical tumor imaging; voice rehabilitation; secondary prevention; multi-omics; biomarkers; precision oncology
Advances in Minimally Invasive Surgery for Gastrointestinal Cancers: Laparoscopic and Robotic Approaches
edited by Beat Peter Müller-Stich and Alexander Wilhelm
submission deadline 31 Aug 2026 | Viewed by 199 | Submission Open
Keywords: minimally invasive surgery; gastrointestinal cancers; laparoscopic surgery; robotic-assisted surgery; surgical oncology; oncologic outcomes; artificial intelligence in surgery; learning curve and training; multimodal cancer care; image-guided surgery
(This special issue belongs to the Section Clinical Research in Cancer)
The Role of the Microbiome in Oral Tumorigenesis
edited by Elena Varoni
submission deadline 31 Aug 2026 | Viewed by 192 | Submission Open
Keywords: oral squamous cell carcinoma; oral potentially malignant disorders; leukoplakia; erythroplakia; oral microbiome; periodontal pathogens; immunotherapy
Detection and Management of Melanoma
edited by
submission deadline 31 Aug 2026 | Viewed by 191 | Submission Open
Keywords: mucosal melanoma; acral melanoma; rare subtypes
Immune–Genomic Interactions and Risk Stratification in Hormone-Receptor-Positive Breast Cancer
edited by Shinichiro Kashiwagi
submission deadline 31 Aug 2026 | Viewed by 175 | Submission Open
Keywords: hormone-receptor-positive breast cancer; oncotype DX; tumor-infiltrating lymphocytes; immune–genomic interaction; clinical–genomic discordance; tumor microenvironment; precision medicine
Cancer Therapy-Related Adverse Events (2nd Edition)
edited by and Pauline Funchain
submission deadline 1 Sep 2026 | 2 articles | Viewed by 10280 | Submission Open
Keywords: cancer; cancer therapy; toxicities; adverse events
(This special issue belongs to the Section Cancer Therapy)
Chronic Lymphocytic Leukemia: From Genetics to Therapy submission deadline 1 Sep 2026 | 6 articles | Viewed by 9075 | Submission Open
Keywords: chronic lymphocytic; leukemia treatment; biology
(This special issue belongs to the Section Cancer Therapy)
The Role of Minimally Invasive and Minimally Radical Surgery in Cervical and Endometrial Cancer
edited by , , Christophe Pomel, and Gwénaël Ferron
submission deadline 1 Sep 2026 | 1 articles | Viewed by 1224 | Submission Open
Keywords: cervical cancer; endometrial cancer; laparoscopic surgery; minimally invasive surgery; surgical oncology; fertility-sparing surgery; non-radical surgery; conservative surgery
(This special issue belongs to the Section Cancer Therapy)
Prostatectomy Today: Surgical Advances in Prostate Cancer Management
edited by
submission deadline 1 Sep 2026 | 1 articles | Viewed by 1201 | Submission Open
Keywords: prostate cancer; robot-assisted radical prostatectomy; robotic system; perioperative outcomes; sexual function; urinary continence; oncological outcomes
(This special issue belongs to the Section Clinical Research in Cancer)
Quality of Care for Patients with Head and Neck Cancer
edited by Khara Marissa Sauro
submission deadline 1 Sep 2026 | 1 articles | Viewed by 1178 | Submission Open
Keywords: patient safety; treatment delays; healthcare resource use; effectiveness; health economics; continuity of care; outcomes research
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Study on Clinical Treatment of Brain Tumors
edited by Shinya Watanabe
submission deadline 9 Sep 2026 | 3 articles | Viewed by 9839 | Submission Open
Keywords: brain tumors; clinical treatment; anti-tumor drugs; clinical trials
(This special issue belongs to the Section Cancer Therapy)
Quality of Life and Side Effects Management in Cancer Treatment (3rd Edition)
edited by
submission deadline 10 Sep 2026 | 9 articles | Viewed by 18431 | Submission Open
Keywords: cancer treatment adverse events; quality of life in cancer patients; chemotherapy adverse events; target therapy adverse events; immunotherapy adverse events; hormonotherapy adverse events; chemotherapy-induced nausea and vomiting; cancer pain
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Exercise and Cancer Treatment: The Clinical Application of Exercise Oncology
edited by and Geovana Leite
submission deadline 10 Sep 2026 | 4 articles | Viewed by 5384 | Submission Open
Keywords: exercise oncology; cancer therapy; immunotherapy; patient outcomes
(This special issue belongs to the Section Clinical Research in Cancer)
Advances in Interventional Oncologic Therapies
edited by Edward W. Lee and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 16235 | Submission Open
(This special issue belongs to the Section Cancer Therapy)
Advances in Artificial Intelligence Methodologies and Applications in Cancer
edited by Jennifer G. Le-Rademacher and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 8639 | Submission Open
Keywords: artificial intelligence (AI); AI tools; cancer research; diagnostic tools; medical imaging; biomarkers; ethical considerations; patient care
(This special issue belongs to the Section Methods and Technologies Development)
First-Line Therapy in Thoracic Oncology
edited by Antonio D'Andrilli and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 7712 | Submission Open
Keywords: thoracic oncology; lung cancer; thymoma; mediastinal tumors
(This special issue belongs to the Section Cancer Therapy)
Robot-Assisted Surgery for Urologic Cancer
edited by Gabriele Sorce, Francesco Pellegrino and Ettore Di Trapani
submission deadline 15 Sep 2026 | 3 articles | Viewed by 7243 | Submission Open
Keywords: robot-assisted surgery; urologic oncology; minimally invasive surgery; prostate cancer surgery; kidney cancer surgery; bladder cancer surgery; robotic platforms; robotic surgery training
(This special issue belongs to the Section Cancer Therapy)
Radiotherapy for Sarcoma
edited by Safia K. Ahmed and Miranda Lam
submission deadline 15 Sep 2026 | 3 articles | Viewed by 5484 | Submission Open
Keywords: soft tissue sarcoma; bone sarcoma; advanced sarcoma; radiation therapy; particle therapy; multidisciplinary sarcoma care
(This special issue belongs to the Section Cancer Therapy)
Endometrial Cancer Therapy: Foundations and Future Directions submission deadline 15 Sep 2026 | 4 articles | Viewed by 4148 | Submission Open
Keywords: pathology; surgery; radiotherapy; chemotherapy; new agents; immunotherapy; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Breast Cancer: Immune Response, Immune Microenvironment, and Immunotherapy submission deadline 15 Sep 2026 | 2 articles | Viewed by 2539 | Submission Open
Keywords: breast cancer; immune response; tumor immune microenvironment; immunotherapy resistance; intrinsic and extrinsic mechanisms; immune checkpoint inhibitors; T-cell dysfunction; cytokines; cancer vaccines; tumor immunosuppression
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Childhood Acute Lymphoblastic Leukemia
edited by Noriko Satake
submission deadline 15 Sep 2026 | 2 articles | Viewed by 1760 | Submission Open
Keywords: childhood acute lymphoblastic leukemia; diagnosis; novel agents; targeted therapy; personalized medicine
(This special issue belongs to the Section Pediatric Oncology)
Evidence-Based Care for Managing Oncologic Emergencies in Patients with Cancer submission deadline 15 Sep 2026 | 1 articles | Viewed by 1455 | Submission Open
Keywords: oncologic emergencies; cancer; urgent; infections; adverse events; thrombosis; febrile neutropenia; pain; spinal cord compression; goals of care
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advances in Endoscopy for Early Detection and Precision Diagnosis of Gastrointestinal Cancers
edited by Ishaan Vohra
submission deadline 15 Sep 2026 | 1 articles | Viewed by 1270 | Submission Open
Keywords: endoscopy; gastrointestinal cancer; early detection; artificial intelligence; advanced imaging; molecular diagnostics; precision medicine; biomarkers; screening; surveillance
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
New Models of Cancer Care to Improve Patient Experiences and Clinical Outcomes
edited by
submission deadline 15 Sep 2026 | 1 articles | Viewed by 1179 | Submission Open
Keywords: patient-centered care; community-based interventions; innovative care models; digital health solutions; patient engagement; clinical outcomes; value-based cancer care
Hepatocellular Carcinoma: Risk Factors, Diagnosis and Treatments submission deadline 15 Sep 2026 | Viewed by 259 | Submission Open
Keywords: chronic hepatitis; cirrhosis; viral hepatitis; HCC; MASLD; imaging; TACE; radio-ablation; chemotherapy
Aptamers Against Cancer submission deadline 15 Sep 2026 | Viewed by 249 | Submission Open
Keywords: aptamers; cancer theranostics; targeted therapy; biosensors; molecular imaging
(This special issue belongs to the Section Methods and Technologies Development)
Onco-Nephrology: From Molecular to Clinical Studies submission deadline 16 Sep 2026 | 1 articles | Viewed by 2440 | Submission Open
Keywords: acute kidney injury in oncology; chronic kidney disease and cancer; paraneoplastic glomerulonephritis; immunotherapy-related nephrotoxicity; tumor lysis syndrome; nephrotoxicity of chemotherapeutic agents; DNA damage; epigenetic modifications; molecular pathways in cancer-associated kidney injury; biomarkers for early detection of kidney injury
(This special issue belongs to the Section Clinical Research in Cancer)
Advances and Innovations in Cancer Drug Therapeutics
edited by
submission deadline 17 Sep 2026 | Viewed by 239 | Submission Open
Keywords: cancer; drug discovery; targeted drugs; computer-aided drug discovery; formulation advances; immunotherapy; transcriptomics; proteomics; metabolomics
(This special issue belongs to the Section Cancer Drug Development)
Artificial Intelligence in Ocular Oncology
edited by
submission deadline 18 Sep 2026 | 3 articles | Viewed by 2850 | Submission Open
Keywords: ocular tumor; eye cancer; artificial intelligence; ophthalmology
(This special issue belongs to the Section Methods and Technologies Development)
Management of Pancreatic Cancer: 2nd Edition
edited by
submission deadline 18 Sep 2026 | 1 articles | Viewed by 703 | Submission Open
Keywords: pancreatic cancer; adenocarcinoma; neuroendocrine carcinomas; molecular and pathological aspects; diagnosis; medical treatment; palliative therapy
Advances in Salivary Gland Carcinoma: 2nd Edition
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 12329 | Submission Open
Keywords: salivary gland tumors; head and neck cancer; facial nerve preservation; facial nerve reconstruction; facial nerve sacrifice; parotid cancer; parotidectomy; prognostic factors
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Clinical Outcomes in Upper GI Cancers
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 3204 | Submission Open
Keywords: esophageal cancer; gastric cancer; esophagogastric junction cancer; surgery; endoscopy; chemotherapy; immuno-therapy; molecural target therapy; biomarker
(This special issue belongs to the Section Clinical Research in Cancer)
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