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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Computational Cancer Biology: Machine Learning for Multi-Omics Integration and Prognosis

edited by Aftab Alam

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1043 | Submission Open

Keywords: multi-omics integration; computational oncology; prognostic biomarkers; machine learning; precision medicine

(This special issue belongs to the Section Methods and Technologies Development)

A New Era in the Treatment of Early-Stage Non-Small Cell Lung Cancer (2nd Edition)

edited by

Tsutani Yasuhiro

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1019 | Submission Open

Keywords: minimally invasive surgery; video-assisted thoracic surgery; robotic-assisted thoracic surgery; sublobar resection; segmentectomy; neoadjuvant therapy; adjuvant therapy; immunotherapy; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Cancer Immunotherapy-Related Adverse Events and Therapy-Related Accelerated Aging

edited by

Grace Lu-Yao

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1017 | Submission Open

Keywords: immune-related adverse events (irAEs); accelerated aging; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in Cancer Targeted Therapy

edited by Ponniah Selvakumar

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1011 | Submission Open

Keywords: targeted therapy; cancer treatment; molecular targets; signaling pathways; angiogenesis inhibition; artificial intelligence (AI); single-cell technologies; informatics; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Translational Advances in Reproductive Cancers: From Targets to Therapies

edited by

Kamila Domińska

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1000 | Submission Open

Keywords: reproductive cancers; signal transduction pathways; hormonal regulation; targeted therapy; therapeutic limitations

(This special issue belongs to the Section Molecular Cancer Biology)

The Tumor Microenvironment and Molecular Aberrations Convey Immune Evasion (Third Edition)

edited by

Huey-Jen Lin

submission deadline 30 Sep 2026 | 1 articles | Viewed by 989 | Submission Open

Keywords: CD8+ tumor-infiltrating lymphocytes; cytotoxic T lymphocytes -associated protein 4; dendritic cells; immune evasion; hypoxia-inducible factors; myeloid-derived suppressor cells; natural killer; programmed death receptor and ligand; regulatory T cells; tumor-associated macrophages; tumor microenvironment

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Psychological Factors and Cancer Survivorship

edited by

Deidre B. Pereira

and Ashley P. Ghiaseddin

submission deadline 30 Sep 2026 | 2 articles | Viewed by 975 | Submission Open

Keywords: psycho-oncology; distress; distress management; biobehavior markers and mechanisms; quality of life outcomes; treatment outcomes; survival outcomes

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Recent Advances in Myeloma: From Molecular Pathways to Drug Development

edited by Natalia Neparidze

submission deadline 30 Sep 2026 | 1 articles | Viewed by 840 | Submission Open

Keywords: myeloma; plasma cell disorders; monoclonal gammopathy; bispecifics; T cell engagers; CART therapy; monoclonal antibodies; MRD

(This special issue belongs to the Section Cancer Drug Development)

Advances in Natural Compounds for Cancers

edited by

Nađa Grozdanić Stanisavljević

and Milica Nedeljković

submission deadline 30 Sep 2026 | 1 articles | Viewed by 834 | Submission Open

Keywords: natural compounds; anticancer activity; molecular mechanisms; synergistic effects; radiosensitizers; radioprotectors; organoids and 3D models; in vivo studies; 2D cell culture; drug resistance

(This special issue belongs to the Section Cancer Drug Development)

Laparoscopic and Robotic Surgery in Gastrointestinal Cancers

edited by Karol Rawicz-Pruszyński

submission deadline 30 Sep 2026 | 1 articles | Viewed by 816 | Submission Open

Keywords: gastric cancer; pancreatic cancer; colorectal cancer; surgical oncology; minimally invasive surgery

(This special issue belongs to the Section Cancer Therapy)

Head and Neck Cancer Therapies: Current and Innovative Options

edited by

Ye Guo

submission deadline 30 Sep 2026 | 1 articles | Viewed by 790 | Submission Open

Keywords: head and neck cancer; multimodal therapy; precision oncology; immunotherapy; antibody–drug conjugates; bispecific antibodies; HPV; salivary gland cancers and sinonasal carcinomas

(This special issue belongs to the Section Cancer Therapy)

Breast Cancer Microenvironment: Molecular Mechanisms and Therapeutic Targeting

edited by Yi Fang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 772 | Submission Open

Keywords: breast cancer; tumor microenvironment; biomarkers; therapeutic targeting; tumor-stromal interactions; precision oncology

(This special issue belongs to the Section Tumor Microenvironment)

Biomarkers in the Management of Gynecological Cancer

edited by Ferenc Bánhidy,

Keszthelyi Márton

and Balázs Lintner

submission deadline 30 Sep 2026 | 1 articles | Viewed by 742 | Submission Open

Keywords: gynecologic cancer; biomarkers; cervical cancer; endometrial cancer; ovarian cancer; vulvar cancer; diagnostic biomarkers; prognostic biomarkers; predictive biomarkers

(This special issue belongs to the Section Cancer Biomarkers)

Risk-Stratified Colorectal Cancer Screening and Surveillance

edited by

Molla Wassie

submission deadline 30 Sep 2026 | 1 articles | Viewed by 710 | Submission Open

Keywords: colorectal cancer; risk stratification; colonoscopy; advanced colorectal neoplasia; precision prevention

Current Status of Neuroendocrine Tumors with a Special Focus on Diagnosis and Novel Treatments—3rd Edition

edited by

Dan Granberg

submission deadline 30 Sep 2026 | 1 articles | Viewed by 693 | Submission Open

Keywords: neuroendocrine tumors; somatostatin analogues; PRRT; chemotherapy; 68Gallium-DOTATOC; PET; CT; targeted therapies; mTOR; inhibitors; angiogenesis

(This special issue belongs to the Section Cancer Therapy)

Strategies and Techniques in Diagnosing, Treating and Surveying Sarcoma

edited by H. Thomas Temple

submission deadline 30 Sep 2026 | 1 articles | Viewed by 686 | Submission Open

Keywords: sarcoma; diagnosis; therapy; treatment; surgery; molecular; radiomics

Emerging Technologies and Clinical Applications in Interventional Oncology

edited by

Mina S. Makary

submission deadline 30 Sep 2026 | 1 articles | Viewed by 653 | Submission Open

Keywords: interventional oncology; emerging technologies; image-guided therapy; ablation; embolotherapy

(This special issue belongs to the Section Methods and Technologies Development)

State of the Art and Advances in Kaposi Sarcoma

edited by

Athanasia Tourlaki

submission deadline 30 Sep 2026 | Viewed by 583 | Submission Open

Keywords: Kaposi sarcoma; human herpes virus 8 (HHV-8); oncogenesis; chemotherapy; targeted therapy; immunotherapy

(This special issue belongs to the Section Clinical Research in Cancer)

Recent Advances in Reconstruction and Surgery for Breast Cancer

edited by

Gilles Houvenaeghel

submission deadline 30 Sep 2026 | 1 articles | Viewed by 537 | Submission Open

Keywords: breast cancer; reconstruction; breast surgery; axillary surgery; sentinel lymph node; neoadjuvant chemotherapy; autologous fat transfer; breast implant

Flow Cytometry and Beyond: Innovative Cytometric Approaches in Cancer Detection, Profiling, and Therapeutic Monitoring

edited by

George Vartholomatos

Georgios Markopoulos

, Lefkothea Dova and Savvas Dimitriadis

submission deadline 30 Sep 2026 | Viewed by 487 | Submission Open

Keywords: cancer diagnostics; next-generation flow cytometry; AI-driven cytometry; high-dimensional single-cell analysis; cancer immunophenotyping; cytometry-based biomarkers; tumor heterogeneity; extracellular vesicles; spectral and mass cytometry; intraoperative flow cytometry

(This special issue belongs to the Section Methods and Technologies Development)

Translational Biomarkers in Solid Tumors: From Diagnosis to Therapy

edited by

Konrad Steinestel

and

Andreea-Raluca Cozac-Szoke

submission deadline 30 Sep 2026 | Viewed by 479 | Submission Open

Keywords: cancer biomarkers; solid tumors; precision oncology; translational research; tumor heterogeneity; primary vs. metastatic disease; therapeutic stratification

Integrated Palliative Care in Advanced Cancer

edited by

Sebastiano Mercadante

submission deadline 30 Sep 2026 | Viewed by 434 | Submission Open

Keywords: integrated palliative care; advanced cancer; cancer pain; symptom management; early integration; supportive care; end-of-life care; patient-centered outcomes; tele-palliative care; refractory symptoms

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Extracellular Matrix Proteins in Cancer (2nd Edition)

edited by

Dragana Nikitovic

and Aikaterini Berdiaki

submission deadline 30 Sep 2026 | Viewed by 423 | Submission Open

Keywords: extracellular matrix (ECM); tumor microenvironment (TME); stromal remodeling; cancer-associated fibroblasts (CAFs); fibrous proteins; mechanotransduction; interstitial fluid pressure; proteoglycans and glycoproteins; matrix crosslinking; epithelial-to-mesenchymal transition (EMT); angiogenesis; matrikines; therapy resistance

(This special issue belongs to the Section Tumor Microenvironment)

Metastasis in Tumor Immunity: Current Perspectives

edited by

Ulrike Stein

, Sebastian Torke and

Wolfgang Walther

submission deadline 30 Sep 2026 | Viewed by 419 | Submission Open

Keywords: immune escape; immune evasion; immune microenvironment; intervention strategies; senescence on metastasis; anti-tumor immunity; cellular interactions; molecular interactions; immune suppression; immune checkpoints

(This special issue belongs to the Section Cancer Metastasis)

Radiation Therapy in Lung Tumors: Recent Trends and Current Issues

edited by

Paul Jules van Houtte

and Sara Ramella

submission deadline 30 Sep 2026 | Viewed by 388 | Submission Open

Keywords: lung cancer; immunotherapy; chemotherapy; PET-CT; surgery; oligo-metastases

(This special issue belongs to the Section Cancer Therapy)

Health-Related Quality of Life in Cancer Survivorship

edited by Deniz Gencer and Elisabeth Coyne

submission deadline 30 Sep 2026 | Viewed by 374 | Submission Open

Keywords: cancer survivorship; health-related quality of life (HRQoL); interventions; psychological support; personalized care; educational resources

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Tumor-Initiating Cells in Cancer: Their Interactions with Other Cell Types, and Prospective Applications

edited by

Spiros Vlahopoulos

submission deadline 30 Sep 2026 | Viewed by 368 | Submission Open

Keywords: cancer stem cells; cancer stem-like cells; leukemia; chromatin; transcription factors; cellular phenotype; microenvironment; immunity; tumor stroma

(This special issue belongs to the Section Tumor Microenvironment)

Medical Image-Based Cervical Cancer Prevention, Diagnosis, and Treatment

edited by Emma R. Allanson and Ming Yin Lin

submission deadline 30 Sep 2026 | Viewed by 358 | Submission Open

Keywords: medical imaging; 3-dimensional imaging; cervical cancer

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Redefining Precision Radiotherapy

edited by Srinivasan Vijayakumar

submission deadline 30 Sep 2026 | Viewed by 345 | Submission Open

Keywords: precision radiotherapy; cancer radiotherapy; PRT; RadioTheronostics

(This special issue belongs to the Section Methods and Technologies Development)

Beyond PEGylation: Next-Generation Nanomedicine for Cancer Therapy

edited by

Soumen Saha

submission deadline 30 Sep 2026 | Viewed by 336 | Submission Open

Keywords: nanomedicine; tumor-targeting mechanisms; cancers

(This special issue belongs to the Section Tumor Microenvironment)

PSMA Targeted Strategies and Radioligand Therapies in Prostate Cancer: From Preclinical Models to Clinical Translation

edited by Neha Vapiwala and John Nikitas

submission deadline 30 Sep 2026 | Viewed by 334 | Submission Open

Keywords: prostate cancer; prostate-specific membrane antigen; radioligand therapy; radiopharmaceutical therapy; radiotherapy; theranostics

(This special issue belongs to the Section Cancer Therapy)

CRLM in the Era of Transplant Oncology: New Hope, New Questions

edited by Brian Davidson and

Khurum Khan

submission deadline 30 Sep 2026 | Viewed by 319 | Submission Open

Keywords: colorectal cancer; liver transplant; transplant oncology; chemotherapy; immunotherapy; immunosuppression; genetic profiling; circulating ccDNA; staging; surveillance

(This special issue belongs to the Section Cancer Therapy)

Targeting JAK/STAT Signaling Pathways for Studying Cancer Pathogenesis, Discovering Cancer Markers, Developing Therapies, and Bypassing Drug Resistance

edited by

Xiaonan Han

submission deadline 30 Sep 2026 | Viewed by 318 | Submission Open

Keywords: JAK-STAT; cancer markers; drug resistance; tumoroids; CAR T-cell therapies

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Clinical Trials and Precision Medicine for Neuro-Oncology

edited by Malaka Ameratunga

submission deadline 30 Sep 2026 | Viewed by 311 | Submission Open

Keywords: clinical trials; neuro-oncology; precision oncology; molecular targets; precision medicine

(This special issue belongs to the Section Clinical Research in Cancer)

Advances in Combination Therapy for Lymphoma

edited by

Maria Christina Cox

submission deadline 30 Sep 2026 | Viewed by 310 | Submission Open

Keywords: lymphoma; combination therapies; T-cell engagers; immuno-conjugates; targeted drugs

(This special issue belongs to the Section Cancer Therapy)

Non-Coding RNAs in Cancer: Molecular Diagnostics and RNA-Based Therapeutics

edited by

Andreas Scorilas

and

Marios A. Diamantopoulos

submission deadline 30 Sep 2026 | Viewed by 304 | Submission Open

Keywords: ncRNAs; miRNAs; lncRNAs; snoRNAs; regulatory RNAs; housekeeping RNAs; cancer biomarkers; RNA-targeted approaches; predictive markers; therapeutics

(This special issue belongs to the Section Molecular Cancer Biology)

Skin Cancer and Environmental Exposure: Unveiling Latest Insights and Future Directions

edited by

Dimitra Koumaki

submission deadline 30 Sep 2026 | Viewed by 290 | Submission Open

Keywords: skin cancer; melanoma; non-melanoma skin cancer; environmental factors; ultraviolet (UV) radiation; DNA damage; etiology; prevention and treatment

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

New Era of Systemic Therapy for Different Types of Skin Cancer

edited by Magdalena Ciazynska

submission deadline 30 Sep 2026 | Viewed by 288 | Submission Open

Keywords: skin cancer systemic therapy; immunotherapy in skin cancer; targeted therapy in skin malignancies; melanoma and nonmelanoma skin cancer; biomarkers and treatment response; resistance mechanisms; combination therapy; real worldreal-world outcomes; novel therapeutic agents; precision oncology

(This special issue belongs to the Section Cancer Therapy)

Therapy in Neuro-Oncology

edited by

Herbert B. Newton

submission deadline 30 Sep 2026 | Viewed by 286 | Submission Open

Keywords: glioma; IDH inhibitor; CAR-T; primary CNS lymphoma; cancer neuroscience; brain metastasis; leptomeningeal disease; molecular classification; pediatric and AYA brain tumors; liquid biopsy; AI; radiation; supportive care

(This special issue belongs to the Section Cancer Therapy)

Next-Generation Cancer Research: AI Approaches for Biomarkers, Therapeutics and Beyond

edited by Wen Zhang

submission deadline 30 Sep 2026 | Viewed by 285 | Submission Open

Keywords: computational genetics; cancer; big data analysis; deep learning; statistical modeling; bioinformatics; AI; biomarkers; therapeutics

(This special issue belongs to the Section Cancer Informatics and Big Data)

New Approaches in the Treatment of Hepatocellular Carcinoma and Liver Tumor: 2nd Edition

edited by Riccardo Inchingolo, Stavros Spiliopoulos and Riccardo Memeo

submission deadline 30 Sep 2026 | Viewed by 280 | Submission Open

Keywords: hepatocellular carcinoma; cirrhosis; liver; interventional oncology; trans-arterial chemo embolization; selective internal radiation therapy; ablation; radiology

(This special issue belongs to the Section Cancer Therapy)

Roles of Circular RNAs (circRNAs) in Cancer Development and Progression

edited by

Qubo Zhu

submission deadline 30 Sep 2026 | Viewed by 270 | Submission Open

Keywords: circular RNAs (circRNAs); cancer development; tumor progression; oncogenesis; gene regulation; metastasis; tumor microenvironment; therapeutic targets; biomarkers; molecular pathways

(This special issue belongs to the Section Molecular Cancer Biology)

The Evolving Landscape of Endometrial Cancer

edited by Dimitrios Zouzoulas and Dimitrios Tsolakidis

submission deadline 30 Sep 2026 | Viewed by 269 | Submission Open

Keywords: endometrial cancer; patient quality of life; fertility preservation; molecular classification; minimal invasive surgery; emerging therapeutic approaches

(This special issue belongs to the Section Molecular Cancer Biology)

Metabolomics Approaches in Cancer Diagnosis

edited by

Raj Kumar Sharma

submission deadline 30 Sep 2026 | Viewed by 264 | Submission Open

Keywords: metabolomics; metabolites; NMR metabolomics; mass spectrometry in metabolomics; cancer biomarkers; metabolomics methods

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Leukemia Stem Cells: Persistence, Resistance, and Novel Eradication Strategies

edited by Elisa Donato and Darja Karpova

submission deadline 30 Sep 2026 | Viewed by 262 | Submission Open

Keywords: leukemia stem cells (LSCs); acute myeloid leukemia (AML); therapeutic resistance; minimal residual disease (MRD); LSC quiescence; cellular therapy; hematopoietic stem cell transplantation (HSCT); LSC microenvironment

Advanced Multimodal Neuroimaging and Computational Approaches in Brain Tumor Research

edited by

Feng Liu

submission deadline 30 Sep 2026 | Viewed by 259 | Submission Open

Keywords: brain tumors; multimodal neuroimaging; artificial intelligence; radiomics; imaging genomics; diffusion MRI; functional MRI; precision oncology

New Clinical Insights into Gynecological Malignancies

edited by

Amelia Jernigan

submission deadline 30 Sep 2026 | Viewed by 259 | Submission Open

Keywords: innovative care; data science; precision medicine; uterine cancer; ovarian cancer; vulvar cancer; vaginal cancer

(This special issue belongs to the Section Cancer Therapy)

Non-Melanoma Skin Cancer: A Growing Problem in the Elderly Population

edited by Jolanta Jaworek and Dariusz Kowalczyk

submission deadline 30 Sep 2026 | Viewed by 257 | Submission Open

Keywords: NMSC; pathomechanism of NMSC; NMSC and gut and/or skin microbiota; NMSC treatment; NMSC diagnosis

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Radiation Therapy for Meningiomas

edited by Helen A. Shih and Lia M. Halasz

submission deadline 30 Sep 2026 | 1 articles | Viewed by 255 | Submission Open

Keywords: radiation therapy; proton radiation; particle therapy; theranostics; brachytherapy; molecular features; advance imaging; late toxicities; quality of life

(This special issue belongs to the Section Cancer Therapy)

Current Treatments of Esophageal and Esophagogastric Junction Cancers (2nd Edition)

edited by

Masanobu Nakajima

submission deadline 30 Sep 2026 | Viewed by 254 | Submission Open

Keywords: esophageal cancer; esophagogastric junction cancer; endoscopic resection; surgery; minimally invasive surgery; robotic surgery; chemotherapy; chemoradiotherapy; immune checkpoint inhibitors

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 251-300 on page 6 of 22.

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