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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Myeloma and Immunology
edited by
submission deadline 30 Jun 2026 | Viewed by 113 | Submission Open
Keywords: multiple myeloma; tumor immunology; immune microenvironment; immunotherapy; CAR-T cells; immune evasion; immune profiling
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Advances in Clinical Treatment of Pancreatic Cancers
edited by
submission deadline 30 Jun 2026 | Viewed by 111 | Submission Open
Keywords: pancreatic cancer; PDAC; neoadjuvant chemotherapy; neuroendocrine tumors; pNET; pancreatic cystic disease; IPMN; pancreatic oligometastases
(This special issue belongs to the Section Clinical Research of Cancer)
Pharmacokinetics in Cancer Treatment
edited by Jing Li
submission deadline 30 Jun 2026 | Viewed by 109 | Submission Open
Keywords: pharmacokinetics (PK); pharmacodynamics (PD); population PK/PD modeling; PBPK modeling; clinical pharmacology; personalized oncology; cancer treatment; pharmacogenetics; molecular pharmacology
(This special issue belongs to the Section Cancer Drug Development)
Research and Treatment of Hepatocellular Carcinoma
edited by Chung Cheung Thomas Yau
submission deadline 30 Jun 2026 | Viewed by 105 | Submission Open
Keywords: hepatobiliary cancer; biomarker; immunotherapy; targeted therapy; combination treatments
(This special issue belongs to the Section Cancer Therapy)
Immunotherapy Approaches in Breast Cancer Treatment (2nd Edition)
edited by Yi Huang and
submission deadline 30 Jun 2026 | Viewed by 104 | Submission Open
Keywords: breast cancer progression; immunotherapy; combination therapy; drug discovery; antitumor immunity; tumor immune microenvironment; biomarkers and clinical trials
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Clinical Application of Proton Therapy and Advanced Radiotherapy in Gynecological Cancer
edited by Amy Tien Yee Chang and
submission deadline 30 Jun 2026 | Viewed by 103 | Submission Open
Keywords: proton therapy; cervical cancer; endometrial cancer; vaginal cancer; MR-guided radiotherapy; MR-guided brachytherapy; stereotactic body radiotherapy
(This special issue belongs to the Section Cancer Therapy)
Contemporary Thoracic Cancer Surgery: Technology and Innovation
edited by
submission deadline 30 Jun 2026 | Viewed by 101 | Submission Open
Keywords: thoracic cancer surgery; robotic-assisted thoracic oncology procedures; video-assisted thoracoscopic surgery for thoracic malignancies; thoracic neoplasms; minimally invasive surgery in cancer treatment; surgical outcomes; lung cancer surgery; surgical innovation in thoracic oncology
(This special issue belongs to the Section Methods and Technologies Development)
Nanocarriers in Cancer Therapy
edited by
submission deadline 30 Jun 2026 | Viewed by 91 | Submission Open
Keywords: nanoparticles; cancer therapy; anticancer drug delivery
(This special issue belongs to the Section Methods and Technologies Development)
Long-Read Sequencing in Cancer (2nd Edition)
edited by and Patrick Driguez
submission deadline 30 Jun 2026 | Viewed by 91 | Submission Open
Keywords: long-read sequencing; cancer genetics; genomics; transcriptomics; methylomics; cancer research
(This special issue belongs to the Section Molecular Cancer Biology)
Prostate Cancer Pathology and Grade submission deadline 30 Jun 2026 | Viewed by 90 | Submission Open
Keywords: prostate cancer; Gleason grading; molecular pathology; artificial intelligence; digital pathology; multimodal algorithms
(This special issue belongs to the Section Cancer Pathophysiology)
Advances in Targeted Therapies and Pharmacogenomics of Leukemia
edited by
submission deadline 30 Jun 2026 | Viewed by 80 | Submission Open
Keywords: blood cancer; targeted therapy; immunotherapy; primary and secondary resistance; pharmacogenetics; combination therapy; tumor microenvironment
(This special issue belongs to the Section Molecular Cancer Biology)
CDK4/6 Inhibitors in Cancer: Efficacy, Resistance, and Combination Approaches
edited by
submission deadline 30 Jun 2026 | Viewed by 78 | Submission Open
Keywords: CDK4/6 inhibitors; palbociclib; abemaciclib; ribociclib; cancer; senescence; combinatorial therapy; prognosis; molecular mechanisms
(This special issue belongs to the Section Cancer Therapy)
Molecular Mechanisms of Cancer Progression and Metastasis
edited by
submission deadline 30 Jun 2026 | Viewed by 71 | Submission Open
Keywords: metastasis; molecular mechanisms; tumor microenvironment (TME); epithelial-to-mesenchymal transition (EMT); cancer stem cell; therapeutic strategies; immune evasion
(This special issue belongs to the Section Cancer Metastasis)
Tumor Heterogeneity in Breast Cancer—the “Omics” Revolution submission deadline 30 Jun 2026 | Viewed by 69 | Submission Open
Keywords: breast cancer; tumor heterogeneity; tumor microenvironment; transcriptional regulation; single-cell RNA-seq; spatial transcriptomics; genomics; epigenomics; proteomics; metabolomics
(This special issue belongs to the Section Molecular Cancer Biology)
Radiation Therapy for Metastatic Cancer
edited by Johnny Kao
submission deadline 30 Jun 2026 | Viewed by 68 | Submission Open
Keywords: metastasis; radiation therapy; tumor agnostic; oligometastases; survivorship; combined modality therapy
(This special issue belongs to the Section Cancer Therapy)
Symptom Burden in Cancer: Assessment and Management: 2nd Edition
edited by Sam M. Salek, and Tatyana Ionova
submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open
Keywords: symptom burden; patient-reported outcomes; symptom assessment; symptom management; cancer survivorship; quality of life
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Progress in Targeted Nanotherapeutic Delivery Systems for Cancer Precision Medicine
edited by and Dhananjay Suresh
submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open
Keywords: cancer therapy; drug delivery; tumor targeting; nanotechnology; precision medicine; immunotherapy; new approach methodologies (NAMs)
(This special issue belongs to the Section Methods and Technologies Development)
Immunotherapy for Acute Lymphoblastic Leukemia: Novel Strategies and Clinical Perspectives
edited by Paola Minetto and
submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open
Keywords: immunotherapy; CAR T-cell therapy; bispecific antibodies; antibody– drug conjugates; treatment resistance; clinical perspectives; clinical trial in ALL
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Magnetic Resonance in Cancer Research (2nd Edition)
edited by Qiuhong He and Marie-France Vidaver
submission deadline 30 Jun 2026 | Viewed by 57 | Submission Open
Keywords: magnetic resonance; cancer; MRI; MRS; MRSI; NMR; DWI; MR; molecular imaging
(This special issue belongs to the Section Methods and Technologies Development)
Ras-Directed Therapies: A Revolution
edited by
submission deadline 30 Jun 2026 | Viewed by 54 | Submission Open
Keywords: Ras-driven cancers; Ras inhibitors; Ras degraders; Ras signaling; mechanisms of resistance; combination therapies
(This special issue belongs to the Section Cancer Therapy)
Fertility and Pregnancy in Cancer
edited by
submission deadline 30 Jun 2026 | Viewed by 38 | Submission Open
Keywords: cancer; gonadotoxic treatment; pregnancy; offspring; long term survivorship; fertility preservation
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Diagnostic and Pathological Markers in Human Cancer
edited by , and Qian Zhao
submission deadline 30 Jun 2026 | Viewed by 15 | Submission Open
Keywords: cancer; biomarker; early diagnosis; pathological markers; prognostic model
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Therapeutic Strategies for Prostate Cancer
edited by Angelo Naselli and
submission deadline 1 Jul 2026 | 5 articles | Viewed by 20548 | Submission Open
Keywords: immunotherapy; radiation therapy; hormone therapy; targeted therapies
(This special issue belongs to the Section Cancer Therapy)
Pediatric Brain Tumors: Symptoms, Diagnosis and Treatments
edited by Christian Ott and Julius Höhne
submission deadline 1 Jul 2026 | 3 articles | Viewed by 7637 | Submission Open
Keywords: MRI/CT scans; radiation therapy; chemotherapy; combined therapy
(This special issue belongs to the Section Cancer Therapy)
The Role of Radiotherapy, Immunotherapy and New Surgical Techniques in the Treatment of Lung Neoplasms
edited by
submission deadline 1 Jul 2026 | 3 articles | Viewed by 7302 | Submission Open
Keywords: radiotherapy; immunotherapy; new surgical techniques; lung cancer
(This special issue belongs to the Section Cancer Therapy)
The Mediastinum—Pandora’s Box
edited by
submission deadline 1 Jul 2026 | Viewed by 537 | Submission Open
Keywords: mediastinum; thymus; imaging; surgery; thymoma; germ cell tumors
Clinical Trials for Diffuse Large B-Cell Lymphomas (DLBCL)
edited by
submission deadline 1 Jul 2026 | Viewed by 315 | Submission Open
Keywords: DLBCL; immunotherapy; drug combinations; elderly patients; ctDNA; biomarkers; radiotherapy; clinical trial management; artificial intelligence
(This special issue belongs to the Section Clinical Research of Cancer)
Advancing CAR-T Cell Therapy: The Next Evolution in Breast Cancer Treatment submission deadline 1 Jul 2026 | Viewed by 172 | Submission Open
Keywords: CAR-T cell therapy; breast cancer; triple-negative breast cancer (TNBC); HER2-positive breast cancer; tumor microenvironment; immunotherapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
The Role of Opioid Therapy for Cancers
edited by Brian Le and
submission deadline 1 Jul 2026 | Viewed by 42 | Submission Open
Keywords: opioids; palliative care; chronic cancer pain
(This special issue belongs to the Section Cancer Therapy)
Metals in Cancer: From Molecular Mechanisms to Innovative Therapeutics submission deadline 5 Jul 2026 | Viewed by 53 | Submission Open
Keywords: essential and toxic metals; metal-induced carcinogenesis; metal homeostasis; metallotherapeutics; oxidative stress; tumor microenvironment; immune modulation; metabolic reprogramming; therapy resistance; drug delivery systems
(This special issue belongs to the Section Molecular Cancer Biology)
Microfluidic Technology in Cancer
edited by and
submission deadline 5 Jul 2026 | Viewed by 52 | Submission Open
Keywords: cancer cells separation; cancer cells isolation; cancer cells treatment; lab-on-a-chip technology; bio microfluidics; biomedical microdevices; biosensors; and detection in microfluidics
(This special issue belongs to the Section Methods and Technologies Development)
Perioperative Management and Cancer Outcomes (2nd Edition)
edited by
submission deadline 9 Jul 2026 | Viewed by 132 | Submission Open
Keywords: perioperative management; cancer treatment outcomes; onco-anesthesiology; preoperative risk assessment; enhanced recovery after surgery (ERAS); pain management; personalized medicine
(This special issue belongs to the Section Cancer Therapy)
Upper Tract Urothelial Carcinoma: Current Knowledge and Perspectives
edited by Katie S. Murray and Saum Ghodoussipour
submission deadline 10 Jul 2026 | 3 articles | Viewed by 7113 | Submission Open
Keywords: upper tract urothelial carcinoma; upper tract disease; urothelial cell carcinoma
(This special issue belongs to the Section Cancer Therapy)
Neuroendocrine Neoplasms: Pathogenesis, Diagnostics, and Therapy
edited by
submission deadline 10 Jul 2026 | 1 articles | Viewed by 5760 | Submission Open
Keywords: neuroendocrine neoplasms; pathogenesis; diagnostics; therapy
(This special issue belongs to the Section Cancer Therapy)
Clinicopathological Study of Gynecologic Cancer (2nd Edition)
edited by
submission deadline 10 Jul 2026 | 1 articles | Viewed by 1172 | Submission Open
Keywords: gynecological oncology; gynecological cancer; female cancer; uterine cancer; ovarian cancer; endometrial cancer; cancerogenesis; cancer biology; cell transformation; cancer pathology; cancer biology
(This special issue belongs to the Section Clinical Research of Cancer)
Beyond Cancer: Enhancing Quality of Life for Cancer Survivors (Second Edition)
edited by , Maryam Lustberg and Muna Al-Khaifi
submission deadline 10 Jul 2026 | Viewed by 71 | Submission Open
Keywords: psychosocial oncology; cancer survivorship; long-term effects of cancer; psychoeducational interventions; nnovative care models; continuing education; knowledge translation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Preoperative Optimisation in Patients Undergoing Cancer Surgery: 2nd Edition
edited by and
submission deadline 10 Jul 2026 | Viewed by 66 | Submission Open
Keywords: prehabilitation; medical optimization; exercise; nutrition; psychological interventions; surgery; cancer; surgical outcome; preoperative; clinical trials
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Molecular Biology, Diagnosis and Management of Endometrial Cancer
edited by , and Thomas Vrekoussis
submission deadline 12 Jul 2026 | 4 articles | Viewed by 8725 | Submission Open
Keywords: endometrial cancer; molecular biology; lymph node dissection; sentinel lymph node mapping; sentinel lymph node dissection; surgery; systemic therapy; radiotherapy; fertility preservation; molecular targeted therapies
(This special issue belongs to the Section Molecular Cancer Biology)
Advances in Hodgkin Lymphoma (HL)
edited by
submission deadline 15 Jul 2026 | 2 articles | Viewed by 3161 | Submission Open
Keywords: classic Hodgkin lymphoma; diagnostic challenges; tumour microenvironment; variability in disease extent; TME-targeted therapies; personalized treatment; relapsed/refractory cHL
(This special issue belongs to the Section Cancer Pathophysiology)
Advances in Clinical Surgery for Gynecological Cancers
edited by
submission deadline 15 Jul 2026 | 1 articles | Viewed by 1559 | Submission Open
Keywords: ovarian cancer; endometrial cancer; cervical cancer; gynecological surgery; gynecological oncology; reconstructive surgery; pelvic exenteration; supportive cancer care
(This special issue belongs to the Section Methods and Technologies Development)
Integrating Chemotherapy and Immunotherapy for Head and Neck Cancer
edited by Ken Saijo
submission deadline 15 Jul 2026 | 1 articles | Viewed by 1467 | Submission Open
Keywords: head and neck squamous cell carcinomas; HNSCC; immune checkpoint inhibitor; biomarker; chemotherapy
(This special issue belongs to the Section Cancer Metastasis)
Penile Cancer and Rare Urogenital Malignancies: From Biology to Clinical Management
edited by and Marcin Matuszewski
submission deadline 15 Jul 2026 | 1 articles | Viewed by 611 | Submission Open
Keywords: penile cancer; urethral carcinoma; upper tract urothelial carcinoma; rare urogenital tumors; surgical management; systemic therapy; epidemiology
Robotic Versus Laparoscopic Surgery for Colorectal Cancer
edited by Richard Garfinkle and Nicholas P. McKenna
submission deadline 15 Jul 2026 | Viewed by 128 | Submission Open
Keywords: colon cancer; rectal cancer; colorectal cancer; robotic surgery; laparoscopic surgery; transanal surgery; minimally invasive surgery
(This special issue belongs to the Section Methods and Technologies Development)
Tumor Microenvironment of Breast Cancer—2nd Edition
edited by
submission deadline 15 Jul 2026 | Viewed by 101 | Submission Open
Keywords: breast cancer; tumor microenvironment; TME; stromal cells
(This special issue belongs to the Section Tumor Microenvironment)
Pancreatic Cancer: Genomics, Therapy and Survival
edited by Hisanobu Ogata
submission deadline 15 Jul 2026 | Viewed by 74 | Submission Open
Keywords: pancreas; cancer; treatment; oncolytic virus; stromal cell; cancer-associated fibroblast (CAF)
(This special issue belongs to the Section Cancer Therapy)
Molecular Signatures of Therapy: Biomarkers Predicting Response and Relapse in Cancer
edited by
submission deadline 15 Jul 2026 | Viewed by 66 | Submission Open
Keywords: molecular biomarkers; therapeutic response; disease relapse; precision oncology; liquid biopsy; predictive biomarkers; multi-omics integration; minimal residual disease; translational oncology
(This special issue belongs to the Section Cancer Biomarkers)
Thermal Ablation in the Management for Colorectal Liver Metastases: 2nd Edition submission deadline 15 Jul 2026 | Viewed by 58 | Submission Open
Keywords: image-guided therapies; colorectal liver metastases (CRLMs); thermal ablation; (non-)thermal and radiation-related treatment; interventional and radiation oncology
(This special issue belongs to the Section Cancer Metastasis)
Myelodysplastic Neoplasms (MDS) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN): New Insights into Diagnosis and Targeted Therapy
edited by , David Sallman and Deniz Peker
submission deadline 15 Jul 2026 | Viewed by 44 | Submission Open
Keywords: myelodysplastic syndromes/myelodysplastic neoplasms (MDS); myelodysplastic/myeloproliferative neoplasm; chronic myelomonocytic leukemia (CMML); diagnosis; mutations; IPSS-R; IPSS-M; hypomethylation agents; targeted therapy; hematopoietic stem cell transplant (HSCT)
(This special issue belongs to the Section Molecular Cancer Biology)
Robotic and Laparoscopic Techniques for Urologic Cancers: Innovations in Resection and Reconstruction
edited by
submission deadline 15 Jul 2026 | Viewed by 40 | Submission Open
Keywords: robot-assisted surgery; surgical robotics; minimally invasive surgery; artificial intelligence; complications; prognostic and predictive factors; planning; perioperative care
(This special issue belongs to the Section Methods and Technologies Development)
Radiologic Imaging of Hepatocellular Carcinomas submission deadline 15 Jul 2026 | Viewed by 36 | Submission Open
Keywords: machine learning/deep learning; radiomics; imaging biomarkers; hepatocellular carcinoma; CT; MRI; PET/CT; Gd-EOB-DTPA; LI-RADS; therapeutic response assessment
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
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