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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Robot-Assisted Surgery for Urologic Cancer
edited by Gabriele Sorce, Francesco Pellegrino and Ettore Di Trapani
submission deadline 15 Mar 2026 | 2 articles | Viewed by 2066 | Submission Open
Keywords: robot-assisted surgery; urologic oncology; minimally invasive surgery; prostate cancer surgery; kidney cancer surgery; bladder cancer surgery; robotic platforms; robotic surgery training
(This special issue belongs to the Section Cancer Therapy)
Novel Approaches to the Management of Patients with Gastrointestinal Tumors
edited by Javier Rodriguez and Ignacio Matos García
submission deadline 15 Mar 2026 | 2 articles | Viewed by 1833 | Submission Open
Keywords: clinical management; gastric cancer; colorectal cancer; predictive factors; novel therapies; artificial intelligence
(This special issue belongs to the Section Methods and Technologies Development)
Radiotherapy for Sarcoma
edited by Safia K. Ahmed and Miranda Lam
submission deadline 15 Mar 2026 | 1 articles | Viewed by 1264 | Submission Open
Keywords: soft tissue sarcoma; bone sarcoma; advanced sarcoma; radiation therapy; particle therapy; multidisciplinary sarcoma care
(This special issue belongs to the Section Cancer Therapy)
Advances in Lung Cancer Treatment Strategies submission deadline 15 Mar 2026 | 1 articles | Viewed by 611 | Submission Open
Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors; chemoimmunotherapy; target therapy; biomarkers; non-small cell lung cancer; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Endometrial Cancer Therapy: Foundations and Future Directions submission deadline 15 Mar 2026 | Viewed by 148 | Submission Open
Keywords: pathology; surgery; radiotherapy; chemotherapy; new agents; immunotherapy; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Stress, Epigenetic Regulation, and DNA Damage: Insights into Cancer Development and Therapeutic Challenges
edited by Yanying Huo
submission deadline 15 Mar 2026 | Viewed by 116 | Submission Open
Keywords: ROS; oxidative stress; metabolic stress; DNA damage repair; genomic instability; cancer
(This special issue belongs to the Section Cancer Pathophysiology)
Treatment of Acute Kidney Injury in Cancer Patients: From Theory to Practice
edited by and Shveta S. Motwani
submission deadline 15 Mar 2026 | Viewed by 98 | Submission Open
Keywords: immune check point inhibitor related nephritis; MGRS; CART cell therapy; stem cell transplant; TMA; BK nephropathy; cisplatin nephropathy
(This special issue belongs to the Section Cancer Therapy)
Renal Cell Carcinoma: Genetics, Surgical Management, and Systemic Therapy
edited by Alejandro Remigio Rodríguez, Stênio C. Zequi and Maxwell Sandberg
submission deadline 15 Mar 2026 | Viewed by 86 | Submission Open
Keywords: renal cell carcinoma; robotics; laparoscopy; systemic therapy; genetics; surgery; urology; disparities; tumor thrombus; cryotherapy; global health
(This special issue belongs to the Section Methods and Technologies Development)
Development of Hepatitis C Virus-Related Cancers
edited by
submission deadline 15 Mar 2026 | Viewed by 62 | Submission Open
Keywords: hepatitis C virus (HCV); hepatocellular carcinoma (HCC); extrahepatic malignancies; lymphoproliferative disorders; viral oncogenesis; chronic inflammation and cancer; direct-acting antivirals (DAAs); cancer surveillance in HCV patients
(This special issue belongs to the Section Clinical Research of Cancer)
Health Economic and Policy Issues Regarding Cancer
edited by Aviad Tur-Sinai
submission deadline 16 Mar 2026 | Viewed by 125 | Submission Open
Keywords: cancer economics; health policy; cost-effectiveness; financial toxicity; healthcare disparities; value-based oncology
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Novel Insight of MRI for Lung Cancer and Thoracic Neoplasm (2nd Edition)
edited by
submission deadline 18 Mar 2026 | Viewed by 167 | Submission Open
Keywords: oncologic imaging; cancer imaging; imaging of thoracic disease; magnetic resonance imaging (MRI); computed tomography (CT); positron emission tomography– computed tomography (PET-CT); diffusion-weighted magnetic resonance imaging (DWI); economic evaluation; imaging biomarkers
(This special issue belongs to the Section Methods and Technologies Development)
Targeted Therapy of Cholangiocarcinoma
edited by
submission deadline 19 Mar 2026 | Viewed by 116 | Submission Open
Keywords: cholangiocarcinoma; targeted therapy; molecular alterations; immunotherapy; precision medicine
(This special issue belongs to the Section Tumor Microenvironment)
Drug Targeting Therapy in Multiple Myeloma submission deadline 20 Mar 2026 | 2 articles | Viewed by 5618 | Submission Open
Keywords: multiple myeloma; novel drug; novel targets; new therapeutic targets; prognosis
(This special issue belongs to the Section Cancer Drug Development)
Hematopoietic Stem Cell Transplant in Hematological Malignancies
edited by and Alessandro Cignetti
submission deadline 20 Mar 2026 | 2 articles | Viewed by 5449 | Submission Open
Keywords: stem cell transplant; graft-versus-host disease; conditioning regimen; prophylaxes; immunology; donors; hematological disease
(This special issue belongs to the Section Cancer Therapy)
Advances in Antibody–Drug Conjugates (ADCs) in Cancers
edited by
submission deadline 20 Mar 2026 | 1 articles | Viewed by 746 | Submission Open
Keywords: antibody– drug conjugates (ADCs); therapeutic efficacy; drug delivery; structural features; disposition; linker design; payload optimization
(This special issue belongs to the Section Cancer Drug Development)
Cancer Induced Organ Dysfunctions (Cachexia)
edited by and Sarama Saha
submission deadline 20 Mar 2026 | Viewed by 463 | Submission Open
Keywords: cancer; cachexia; organ dysfunction; cancer-induced cachexia; cancer-induced organ dysfunction; muscle wasting
(This special issue belongs to the Section Molecular Cancer Biology)
Cancer Survivors: Late Effects of Cancer Therapy
edited by
submission deadline 20 Mar 2026 | Viewed by 127 | Submission Open
Keywords: late effects; cancer survivorship; treatment toxicity; long-term outcomes
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Neuroendocrine Tumors: From Diagnosis to Therapy (2nd Edition)
edited by , , and Daniela Prosperi
submission deadline 20 Mar 2026 | Viewed by 107 | Submission Open
Keywords: neuroendocrine neoplasms; CT; MR; PET/CT; target therapy; quantitative biomarkers
(This special issue belongs to the Section Cancer Therapy)
Cervical Cancer Screening: Current Practices and Future Perspectives
edited by Kimon Chatzistamatiou
submission deadline 20 Mar 2026 | Viewed by 103 | Submission Open
Keywords: cervical cancer screening; cervical carcinogenesis; human papillomavirus; HPV primary screening; self-sampling; triage of HPV-positive; post-conization follow-up; screening for immunocompromised women; screening for vac-cinated women
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Artificial Intelligence in Ocular Oncology
edited by
submission deadline 20 Mar 2026 | Viewed by 68 | Submission Open
Keywords: ocular tumor; eye cancer; artificial intelligence; ophthalmology
(This special issue belongs to the Section Methods and Technologies Development)
Radiation Therapy in Lung Tumors: Recent Trends and Current Issues
edited by and Sara Ramella
submission deadline 21 Mar 2026 | Viewed by 69 | Submission Open
Keywords: lung cancer; immunotherapy; chemotherapy; PET-CT; surgery; oligo-metastases
(This special issue belongs to the Section Cancer Therapy)
Bacterial Infections and Cancer Risk: From Biological Mechanisms to Clinical Realities
edited by and Shuai Hu
submission deadline 25 Mar 2026 | 1 articles | Viewed by 1430 | Submission Open
Keywords: bacterial infections; cancer risk; biological mechanisms; treatment modalities; therapeutic strategies
(This special issue belongs to the Section Infectious Agents and Cancer)
Acute Myeloid Leukemia: Updates on Diagnosis and Novel Management Strategies
edited by Ana Vidović
submission deadline 25 Mar 2026 | Viewed by 7 | Submission Open
Keywords: acute myeloblastic leukemia; diagnosis; prognosis; intensive chemotherapy; target therapy; allogeneic stem cell transplantation
(This special issue belongs to the Section Clinical Research of Cancer)
Roles of Urokinase Receptors in Cell Biology: Modulating Tumor Cell Migration and Invasion
edited by
submission deadline 28 Mar 2026 | Viewed by 129 | Submission Open
Keywords: urokinase-type plasminogen receptor; uPAR; inflammation; cancer; migration; invasion
(This special issue belongs to the Section Molecular Cancer Biology)
Cancer Immunotherapy: Focus on Immune Checkpoint Inhibitors and Immune Modulators
edited by
submission deadline 30 Mar 2026 | 4 articles | Viewed by 8946 | Submission Open
Keywords: PD-1; PD-L1; CTLA-4; immune checkpoint molecule; immune checkpoint inhibitor; tumor microenvironment; drug resistance; biomarker; BiTE; BiCE
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Quality and Clinical Outcomes Improvement in the Management of Oncology Patients (2nd Edition) submission deadline 30 Mar 2026 | 1 articles | Viewed by 901 | Submission Open
Keywords: oncology; surgical oncology; quality improvement; clinical outcomes; patient safety
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Neoadjuvant Therapy for Pancreatic Cancer
edited by Brice Chanez
submission deadline 30 Mar 2026 | Viewed by 160 | Submission Open
Keywords: induction treatment; biomarkers; chemotherapy
(This special issue belongs to the Section Cancer Therapy)
Women’s Health and Gynaecological Cancers: From Nutrition and Environmental Factors to Novel Diagnostics and Therapies submission deadline 31 Mar 2026 | 10 articles | Viewed by 26905 | Submission Open
Keywords: breast cancer; ovarian cancer; cervical cancer; endometrial cancer; nutrition; obesity; environmental factors; women's health; gynaecological cancers
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Recent Advances in Hepatobiliary Cancers: From Diagnosis to Treatment (2nd Edition)
edited by
submission deadline 31 Mar 2026 | 10 articles | Viewed by 21703 | Submission Open
Keywords: hepatobiliary cancers; hepatocellular carcinoma; cholangiocarcinoma; gallbladder cancer; immunotherapy; targeted therapy; precision medicine
(This special issue belongs to the Section Cancer Therapy)
PET/CT and Conventional Imaging in Cancers submission deadline 31 Mar 2026 | 7 articles | Viewed by 13761 | Submission Open
Keywords: PET/CT; CT; MR; conventional imaging; positron emission tomography; neoplasm; cancer
(This special issue belongs to the Section Methods and Technologies Development)
Gastric Cancer Surgery: Gastrectomy, Risk, and Related Prognosis submission deadline 31 Mar 2026 | 5 articles | Viewed by 8496 | Submission Open
Keywords: gastric cancer; surgical treatment; gastrectomy; outcome; minimally invasive surgical
(This special issue belongs to the Section Clinical Research of Cancer)
Biomarkers for Gynecological Cancers submission deadline 31 Mar 2026 | 6 articles | Viewed by 8305 | Submission Open
Keywords: biomarkers; cervical; ovarian; uterine; endometrial; vaginal; vulvar; fallopian tube
(This special issue belongs to the Section Cancer Biomarkers)
Advances in Invasive Breast Cancer: Treatment and Prognosis (2nd Edition)
edited by and Emmanouil Saloustros
submission deadline 31 Mar 2026 | 6 articles | Viewed by 7903 | Submission Open
Keywords: ER+/HER2– breast cancer; HER2+ breast cancer; triple-negative breast cancer; treatment toxicity and quality of life; survivorship issues
(This special issue belongs to the Section Cancer Therapy)
Cardio-Oncology: An Emerging Paradigm in Modern Medicine: 2nd Edition
edited by Rohit Moudgil
submission deadline 31 Mar 2026 | 5 articles | Viewed by 5617 | Submission Open
Keywords: cardio-oncology; CTRCD; arrhythmias; anthracyclines; anti-her2 therapies; immune checkpoint inhibitors; artificial intelligence; guidelines; emerging research
(This special issue belongs to the Section Cancer Therapy)
Advancements in Treatment Approaches for AML submission deadline 31 Mar 2026 | 3 articles | Viewed by 5472 | Submission Open
Keywords: AML treatment; allogeneic HSCT; novel targeted therapeutic agents; diagnostic; treatment strategies
(This special issue belongs to the Section Methods and Technologies Development)
Current Use of Hematopoietic Cell Transplantation in Hematologic Malignancies
edited by Marina Díaz-Beyá and Maria Queralt Salas
submission deadline 31 Mar 2026 | 4 articles | Viewed by 4685 | Submission Open
Keywords: allogeneic hematopoietic cell transplantation; hematologic malignancies; minimal residual disease; patient selection; conditioning regimens; graft-versus-host disease prophylaxis; immunotherapy; targeted treatments; real-world data; acute myeloid leukemia; myelodysplastic syndrome; chronic myelomonocytic leukemia; allogeneic hematopoietic cell transplantation
(This special issue belongs to the Section Transplant Oncology)
Advances in Renal Cell Carcinoma
edited by Philipp Ivanyi and Hendrik Eggers
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3966 | Submission Open
Keywords: renal cell carcinoma; treatment; metastatic; prediction; medical treatment; immunotherapy; multimodal therapy; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
The Oral Microbiome and Its Link to Oral Cancer: Exploring the Role of Infectious Agents
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 3776 | Submission Open
Keywords: oral microbiome; oral cancer; infectious agents; microbial dysbiosis; host– microbe interactions
(This special issue belongs to the Section Infectious Agents and Cancer)
Immunotherapy in Urothelial Carcinoma
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 3465 | Submission Open
Keywords: bladder cancer; upper tract urothelial carcinoma; immune checkpoint inhibitors; tumor microenvironment; biomarkers for immunotherapy; combination therapy; neo-adjuvant/adjuvant immunotherapy; resistance mechanisms; novel immunotherapeutic approaches; personalized medicine
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Intratumoral Heterogeneity in Brain Cancers
edited by Michael Oldham
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2826 | Submission Open
Keywords: intratumoral heterogeneity; brain; clonal evolution; tumor microenvironment; multiomics
(This special issue belongs to the Section Molecular Cancer Biology)
Colorectal Cancer Liver Metastases submission deadline 31 Mar 2026 | 2 articles | Viewed by 2801 | Submission Open
Keywords: liver metastases; colorectal cancer; treatment; imaging; oncologic strategy
(This special issue belongs to the Section Cancer Metastasis)
Significance of KRAS Gene Mutations in Colorectal Cancer (2nd Edition) submission deadline 31 Mar 2026 | 2 articles | Viewed by 2497 | Submission Open
Keywords: KRAS; colorectal cancer; target therapy; mechanism; treatment targets
(This special issue belongs to the Section Molecular Cancer Biology)
The EGFR-Tyrosine Kinase Inhibitors (EGFR-TKIs) and Immune Checkpoint Inhibitors (ICIs) for Non-Small Cell Lung Cancer submission deadline 31 Mar 2026 | 2 articles | Viewed by 2314 | Submission Open
Keywords: non-small cell lung cancer; target therapy; EGFR-tyrosine kinase inhibitors; immunotherapy; immune checkpoint inhibitors; molecular analysis; surgery; precision medicine
(This special issue belongs to the Section Cancer Therapy)
The Role of Viruses in the Development of Cancer
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1721 | Submission Open
Keywords: DNA and RNA tumour viruses; HPV; EBV; KSHV; HCV; HBV; HTLV1; McPyV
(This special issue belongs to the Section Infectious Agents and Cancer)
Cancer Drug Discovery and Development: 2nd Edition
edited by Gary Piazza
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1526 | Submission Open
Keywords: signal transduction inhibitors; small-molecule inhibitors; antibodies; PROTOC; immunotherapy; medicinal chemistry; chemical optimization; high-throughput screening
(This special issue belongs to the Section Cancer Drug Development)
Minimally Invasive Therapies in Urologic Cancers
edited by Eric M. Walser and
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1327 | Submission Open
Keywords: laparoscopic surgery; robotic-assisted surgery; ablation; high-intensity focused ultrasound; partial nephrectomy; minimally invasive procedures; urologic cancers
(This special issue belongs to the Section Methods and Technologies Development)
Development of Biomarkers and Antineoplastic Drugs in Solid Tumors
edited by , Sofia Verkhovskaia and Michela Roberto
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1095 | Submission Open
Keywords: solid tumors; drugs; biomarkers; immunotherapy; targeted therapy; artificial intelligence
(This special issue belongs to the Section Cancer Drug Development)
Multiple Myeloma: Diagnosis and Therapy submission deadline 31 Mar 2026 | 1 articles | Viewed by 1035 | Submission Open
Keywords: multiple myeloma; plasma cell disorders; relapsed and refractory multiple myeloma; blood and marrow transplant
(This special issue belongs to the Section Cancer Therapy)
The Development of Immunotherapies to Treat Lymphoma submission deadline 31 Mar 2026 | 1 articles | Viewed by 991 | Submission Open
Keywords: lymphoma immunotherapy; CAR T-cell therapy; immune checkpoint inhibitors; monoclonal antibodies; personalized immunotherapy
Genetic Alterations and the Tumor Microenvironment
edited by Shanye Yin
submission deadline 31 Mar 2026 | 1 articles | Viewed by 913 | Submission Open
Keywords: tumor microenvironment; cancer immunology; immune checkpoint blockade; somatic mutations; T cell signaling; immune evasion; macrophage polarization; cancer immunotherapy resistance; single-cell transcriptomics; spatial analysis
(This special issue belongs to the Section Tumor Microenvironment)
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