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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Flow Cytometry in Acute Leukemia: From Diagnosis to Disease Monitoring

edited by

Donatella Raspadori

and

Paola Pacelli

submission deadline 31 May 2026 | Viewed by 27 | Submission Open

Keywords: acute leukemia; ALL; AML; flow cytometry; NGF; leukemia stem cells (LSCs; minimal residual disease (MRD)

(This special issue belongs to the Section Methods and Technologies Development)

Evolving Role of Surgery in Thoracic Oncology

edited by Inderpal S. Sarkaria and Shamus Carr

submission deadline 31 May 2026 | Viewed by 24 | Submission Open

Keywords: non-small cell lung cancer; esophageal cancer; thymic epithelial tumors; BAP1 malignant mesothelioma; robotic surgery; immunotherapy; cellular therapies; molecular imaging

T-Cell Lymphoma: From Diagnosis to Treatment

edited by Lubomir Sokol and Yumeng Zhang

submission deadline 31 May 2026 | Viewed by 22 | Submission Open

Keywords: cutaneous T-cell lymphomas (CTCLs); peripheral T-cell lymphomas (PTCLs); Sezary syndrome (SS); mycosis fungoides (MF); genetic; epigenetic; therapeutic strategies

Machine Learning and Artificial Intelligence in Leukemia

edited by Garrett M. Dancik and

Spiros Vlahopoulos

submission deadline 31 May 2026 | Viewed by 22 | Submission Open

Keywords: cancer genomics; genomic sequencing; biomarkers; predictive modeling; machine learning; artificial intelligence; leukemia; computer vision; natural language processing

(This special issue belongs to the Section Methods and Technologies Development)

The Intelligent Scalpel: AI and the Future of Cancer Surgery

edited by Abdallah S. Attia and Kristen E. Limbach

submission deadline 31 May 2026 | Viewed by 19 | Submission Open

Keywords: artificial intelligence; surgical oncology; radiomics; pathomics; robotic surgery; large language models; multimodal learning; explainable AI; precision surgery; ethical AI

(This special issue belongs to the Section Methods and Technologies Development)

Multimodality Imaging for More Precise Radiotherapy (2nd Edition)

edited by Stefano Arcangeli,

Denis Panizza

and

Valeria Faccenda

submission deadline 31 May 2026 | Viewed by 16 | Submission Open

Keywords: multimodality imaging; radiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Breast Cancer and Hormone-Related Therapy: 2nd Edition

edited by

John R. Hawse

submission deadline 31 May 2026 | Viewed by 11 | Submission Open

Keywords: breast cancer; estrogen receptor; hormone activated transcription factors; hormonal therapy; molecular mechanisms

(This special issue belongs to the Section Cancer Therapy)

What’s Behind the Scenes? New Insights in Endometrial Cancer Management and Risk Stratification (2nd Edition)

edited by

Emanuele Perrone

submission deadline 31 May 2026 | Viewed by 9 | Submission Open

Keywords: endometrial cancer; molecular classification; surgical staging; surgery; target therapy; gynecologic oncology; precision medicine; immunohistochemistry

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Updates on Progress in Stem-Cell Transplantation in Cancer Patients

edited by Nidhi Jyotsana

submission deadline 31 May 2026 | Viewed by 5 | Submission Open

Keywords: hematopoietic stem cell transplantation (HSCT); acute myeloid leukemia (AML); leukemic stem cells; optimize transplant protocols

(This special issue belongs to the Section Transplant Oncology)

The Role of Medical Imaging in Gynecological Cancer

edited by Emma R. Allanson and Ming Yin Lin

submission deadline 1 Jun 2026 | 6 articles | Viewed by 14923 | Submission Open

Keywords: cervical cancer; endometrial cancer; ovarian cancer; staging; ultrasound; MRI; PET-CT; radiotherapy; image-guided brachytherapy

(This special issue belongs to the Section Methods and Technologies Development)

Drug Repurposing and Reformulation for Cancer Treatment: 2nd Edition

edited by

Arati Sharma

Dhimant Desai

and

Abhijit Date

submission deadline 1 Jun 2026 | 2 articles | Viewed by 13679 | Submission Open

Keywords: drug repurposing; cancer; drug resistance; metastasis; drug delivery; liposomes; nanoparticles; bioavailability; drug targeting; reformulation

(This special issue belongs to the Section Cancer Drug Development)

New Developments in Breast Cancer Surgery, Risk, and Related Quality of Life

edited by Vesna Bjelic-Radisic,

Maggie Banys-Paluchowski

and Constanze Elfgen

submission deadline 1 Jun 2026 | 3 articles | Viewed by 5615 | Submission Open

Keywords: oncoplastic breast surgery; breast reconstruction; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Proton Therapy of Cancer Treatment

edited by Minglei Kang, Benjamin Durkee and Kuo Men

submission deadline 1 Jun 2026 | 3 articles | Viewed by 4471 | Submission Open

Keywords: proton therapy; FLASH radiotherapy; upright; pediatric cancer; head and neck cancer; affordable proton solutions; adaptive radiation therapy; treatment planning optimization; proton system commissioning

(This special issue belongs to the Section Cancer Therapy)

Looking for New Biochemical Mechanisms in Cancer: The New Dawn in the Omics Sciences

edited by

Alessia Maria Cossu

, Marco Bocchetti and

Michela Falco

submission deadline 1 Jun 2026 | 1 articles | Viewed by 2690 | Submission Open

Keywords: multi-omics; machine learning; sequencing; signal transduction; molecular mechanisms; circulating biomarker; cancer

(This special issue belongs to the Section Molecular Cancer Biology)

Stereotactic Radiosurgery for Malignant Brain Tumors

edited by Stylianos Pikis, Jason P. Sheehan,

Yuki Shinya

and Georgios Mantziaris

submission deadline 1 Jun 2026 | Viewed by 273 | Submission Open

Keywords: radiosurgery; brain metastases; low-grade gliomas; high-grade gliomas; glioblastoma; malignant meningiomas

(This special issue belongs to the Section Clinical Research of Cancer)

Novel Developments in Invasive Lobular Breast Cancer: Diagnosis, Prognosis and Therapy (2nd Edition)

edited by

Lubna Khaldi

and

Nektarios Koufopoulos

submission deadline 1 Jun 2026 | Viewed by 193 | Submission Open

Keywords: invasive lobular carcinoma; imaging; diagnosis; pathology; tumor microenvironment; treatment; metastasis

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Gastrointestinal Tumors: Prevention, Screening and Predictive Analytics

edited by Mohamed I. Elsaid,

Electra D. Paskett

and Vinod Rustgi

submission deadline 1 Jun 2026 | Viewed by 53 | Submission Open

Keywords: gastrointestinal and hepatobiliary cancers; prevention and screening; chemoprevention; risk stratification; biomarkers and liquid biopsy (ctDNA); imaging and radiomics; predictive analytics and machine learning; causal inference; population-based studies; implementation science and health equity

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Neurofibromatosis in Children, Adolescents, and Young Adults

edited by

Pamela L. Wolters

Andrea M. Gross

and Russell Taylor Sundby

submission deadline 1 Jun 2026 | Viewed by 18 | Submission Open

Keywords: neurofibromatosis; schwannomatosis; natural history; clinical trials; targeted therapy; outcomes; psychosocial; biomarkers; pediatric

Advances in the Immunotherapy of Metastatic Cancer

edited by

Gianluca Tomasello

submission deadline 5 Jun 2026 | Viewed by 84 | Submission Open

Keywords: metastatic cancer; immunotherapy; immune checkpoint inhibitors; CAR-T cells; tumor microenvironment; immune-related adverse events; biomarkers; combination therapy; resistance mechanisms

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

New Insights in Thymic Tumors

edited by Till Ploenes

submission deadline 5 Jun 2026 | Viewed by 40 | Submission Open

Keywords: thymic tumors; thymic carcinoma; thymomas; new daignostic and therapeutic approaches; myasthenia gravis

Research on New Drugs and Drug Targets in Melanoma: 2nd Edition

edited by

Paula Wróblewska Łuczka

and

Nicolas Dumaz

submission deadline 5 Jun 2026 | Viewed by 24 | Submission Open

Keywords: melanoma; new drugs; drug targets; mechanism of action; substances with anti-melanoma potential

(This special issue belongs to the Section Cancer Drug Development)

Surgical Advances in the Treatment of Gliomas: Preserving Function and Quality of Life

edited by Francesco Vergani and José Pedro Lavrador

submission deadline 7 Jun 2026 | 3 articles | Viewed by 4687 | Submission Open

Keywords: neuro-oncology; brain mapping; neuroimaging; intraoperative neuro-monitoring; functional MRI; transcranial magnetic stimulation; neurorehabilitation

(This special issue belongs to the Section Cancer Therapy)

Histopathology of Urological Cancers

edited by Vikas Mehta, Antoun Toubaji and Vijayalakshmi Ananthanarayanan

submission deadline 10 Jun 2026 | 3 articles | Viewed by 7863 | Submission Open

Keywords: renal cell carcinoma; prostate; testis Ggrm cell tumors; urothelial carcinoma; artificial intelligence; ductal adenocarcinoma of prostate; neuroendocrine differentiation of prostate carcinoma; next-generation sequencing

(This special issue belongs to the Section Cancer Pathophysiology)

Existing and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors (2nd Edition)

edited by Nuria Romero-Laorden

submission deadline 10 Jun 2026 | 2 articles | Viewed by 5774 | Submission Open

Keywords: immunotherapy; checkpoint inhibitors; biomarkers; immune biomarkers; PD-L1; TMB; solid tumors

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Emerging Concepts in Mesothelioma

edited by Georgios T. Stathopoulos and Tonia Adamides

submission deadline 10 Jun 2026 | 1 articles | Viewed by 1174 | Submission Open

Keywords: mesothelioma; asbestos; pleura; tumor suppressor; cell lines; patient-derived xenograft; surgery; chemotherapy; folate antagonist; immunotherapy

(This special issue belongs to the Section Clinical Research of Cancer)

Diagnosis of Hematologic Malignancies: 2nd Edition

edited by

Leonor Arenillas

and

Xavier Calvo

submission deadline 10 Jun 2026 | Viewed by 177 | Submission Open

Keywords: diagnosis of hematologic malignancies; myeloid neoplasms; lymphoid neoplasms; cytomorphology; flow cytometry; cytogenetic; molecular biology

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Extracellular Vesicles in Cancer Progression

edited by

Susana García-Silva

submission deadline 10 Jun 2026 | Viewed by 100 | Submission Open

Keywords: extracellular vesicles; cancer progression; tumor microenvironment; tumor– immune landscape; cross-talk pre-metastatic and metastatic niches immune surveillance; EV-based biomarkers; EV-based therapeutic development

(This special issue belongs to the Section Tumor Microenvironment)

Systematic Reviews and Meta-Analyses in Cancer Research: The Therapeutic Potential of Phytochemicals and Bioactive Compounds with Defined Mechanisms and Safety Profiles

edited by

Lucas Fornari Laurindo

submission deadline 10 Jun 2026 | Viewed by 80 | Submission Open

Keywords: phytochemicals in cancer therapy; bioactive natural compounds; systematic reviews and meta-analyses; molecular mechanisms of anticancer agents; translational oncology; pharmacokinetics and toxicity of natural products; evidence-based integrative oncology; natural product drug discovery; chemoprevention and cancer therapeutics; mechanistic and safety profiling of phytochemicals

(This special issue belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)

Innovative Surgical Strategies for Thoracic Malignancies

edited by

Gregor J. Kocher

and

Fabrizio Minervini

submission deadline 10 Jun 2026 | Viewed by 60 | Submission Open

Keywords: robotic thoracic surgery; RATS; uRATS; NSCLC; thoracic malignancies; video-assisted thoracic surgery; VATS; uVATS

(This special issue belongs to the Section Methods and Technologies Development)

Precision Cell Therapy in Cancer: From Molecular Profiling to Personalized Treatment

edited by

Biaoru Li

submission deadline 10 Jun 2026 | Viewed by 17 | Submission Open

Keywords: molecular profiling; precision cell therapy; Next-Generation Sequencing (NGS); biomarker identification; CAR T-cell therapy

(This special issue belongs to the Section Cancer Therapy)

Nursing and Supportive Care for Cancer Survivors

edited by

Michela Piredda

submission deadline 12 Jun 2026 | 2 articles | Viewed by 2406 | Submission Open

Keywords: cancer survivorship; oncology nursing; symptom management; quality of life; supportive care; psycho-existential distress; pain catastrophizing; palliative care; caregiver support; advanced cancer; patient-centred care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Brain Metastases: From Mechanisms to Treatment

edited by Dawen Zhao and Michael Chan

submission deadline 15 Jun 2026 | 7 articles | Viewed by 16019 | Submission Open

Keywords: brain metastasis; the tumor microenvironment; blood– tumor barrier; novel biomarkers and therapeutics; radiation therapy

(This special issue belongs to the Section Cancer Metastasis)

Recent Studies on Oral Cancer: Diagnostic Technologies, Pathology, and Surgery

edited by

Luisa Limongelli

Gianfranco F. Favia

and

Fabio Dell’Olio

submission deadline 15 Jun 2026 | 4 articles | Viewed by 7326 | Submission Open

Keywords: oral cancer; oral squamous cell carcinoma; oral potentially malignant disorders; diagnostic technologies; oral surgery; maxillo-facial surgery; oncology; radiology; immunohistochemistry; molecular biology

(This special issue belongs to the Section Clinical Research of Cancer)

Application of Large-Scale Genome Data in Identifying Clinically Actionable Targets in Cancer

edited by

Arezou A. Ghazani

submission deadline 15 Jun 2026 | 3 articles | Viewed by 4454 | Submission Open

Keywords: genome; cancers; oncology

(This special issue belongs to the Section Molecular Cancer Biology)

Metastatic Progression of Human Melanoma: 2nd Edition

edited by

Jozsef Timar

and

Andrea Ladányi

submission deadline 15 Jun 2026 | 2 articles | Viewed by 2794 | Submission Open

Keywords: human melanoma; metastasis models; oncogenic signaling; organ metastasis; genomics; immune microenvironment; prognosticators; predictors of target therapies

(This special issue belongs to the Section Cancer Pathophysiology)

Current Updates and Future Directions in Neuroendocrine Neoplasms (NENs): Understanding Biology, Diagnosis, Management and Research Efforts in NENs (2nd Edition)

edited by

Jaydira del Rivero

and Aman Chauhan

submission deadline 15 Jun 2026 | 1 articles | Viewed by 2724 | Submission Open

Keywords: neuroendocrine neoplasms; NENs; neuroendocrine carcinomas; tumor biology; clinical management; therapeutic management

(This special issue belongs to the Section Cancer Therapy)

Advances in Radiotherapy of Gastrointestinal Cancers

edited by

Sunil Krishnan

submission deadline 15 Jun 2026 | Viewed by 122 | Submission Open

Keywords: gastrointestinal cancer; radiotherapy; IMRT; SBRT; MR-guided; proton therapy; adaptive radiotherapy; treatment planning; radiomics; artificial intelligence; combination therapy; immunotherapy; toxicity management; quality of life; personalized medicine

(This special issue belongs to the Section Methods and Technologies Development)

Nanocarriers as an Emerging Platform for Cancer Therapy

edited by

Andrea Markus

and Fernanda Ramos-Gomes

submission deadline 15 Jun 2026 | Viewed by 114 | Submission Open

Keywords: nanoparticles; cancer therapy; nanomedicine; theranostics; chemotherapy; nanocarriers; drug delivery; nanotechnology

(This special issue belongs to the Section Cancer Therapy)

Surgical Strategies in the Era of Perioperative Immunotherapy for Thoracic Cancer

edited by Tomoyuki Hishida

submission deadline 15 Jun 2026 | Viewed by 78 | Submission Open

Keywords: lung cancer; perioperative treatment; immunotherapy; innmue checkpoint inhibitors; surgery

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Current Progress in Radiotherapy and Particle Therapy of Cancer

edited by

Carla Hajj

submission deadline 16 Jun 2026 | Viewed by 182 | Submission Open

Keywords: radiotherapy; particle therapy; proton therapy; heavy ion therapy; radiobiological; carbon ion therapy

(This special issue belongs to the Section Cancer Therapy)

Novel Insights into Cancer-Related Cognitive Impairment

edited by Danielle Tometich

submission deadline 20 Jun 2026 | 3 articles | Viewed by 6427 | Submission Open

Keywords: cognitive impairment; cognitive dysfunction; cancer survivorship; quality of life; neuropsychological assessment; cognitive rehabilitation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Sarcoma Management in Orthopaedic Oncology

edited by

Vasileios Kontogeorgakos

and Jendrik Hardes

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3146 | Submission Open

Keywords: orthopaedic surgical oncology; sarcoma; orthopaedic surgery; bone and soft tissue sarcoma; diagnose; neoadjuvant therapy; targeted therapy; immunotherapy

(This special issue belongs to the Section Methods and Technologies Development)

The Advance of Clinical Therapy and Prognosis in Gastrointestinal Cancer

edited by Liliana Streba and Michael Schenker

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2208 | Submission Open

Keywords: gastrointestinal cancer; tumorigenesis; microbiome; early detection; molecular mechanisms; personalized medicine; novel therapeutics; translational research; clinical application; diagnostic innovations

(This special issue belongs to the Section Clinical Research of Cancer)

p53 Family in Cancer: How Close Are We to the Clinic? (2nd Edition)

edited by

Lucília Saraiva

and

Marco M. Candeias

submission deadline 20 Jun 2026 | 1 articles | Viewed by 697 | Submission Open

Keywords: p53; p63; p73; proteins; protein-coding and non-coding genes; genetics; drug discovery; cancer; targeted anticancer therapy

(This special issue belongs to the Section Cancer Therapy)

Advances in Pleural and Peritoneal Mesothelioma

edited by

Rossella Bruno

submission deadline 20 Jun 2026 | Viewed by 304 | Submission Open

Keywords: pleural mesothelioma; peritoneal mesothelioma; differential diagnosis; biomarkers; next-generation sequencing; gene expression

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in the Ubiquitin–Proteasome System (UPS) in Cancer Biology

edited by

Tarek A. Abbas

submission deadline 20 Jun 2026 | Viewed by 138 | Submission Open

Keywords: ubiquitin– proteasome system (UPS); cancer biology; E3 ubiquitin ligases; deubiquitinating enzymes (DUBs); protein degradation; proteasome inhibitors; ubiquitination signaling; genome stability and DNA repair; PROTACs and molecular glues; targeted cancer therapeutics

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Squamous Cell Carcinoma: From Pathogenesis to Treatment

edited by Carolin Götz

submission deadline 20 Jun 2026 | Viewed by 131 | Submission Open

Keywords: squamous cell carcinoma (SCC); oncological surgery; carcinogenesis; tumor microenvironment; HPV; immunotherapy; molecular targets; precision oncology; biomarkers; head and neck cancer; translational oncology

(This special issue belongs to the Section Cancer Pathophysiology)

Genetic Predisposition to Hematological Malignancies

edited by

Danika Di Giacomo

submission deadline 20 Jun 2026 | Viewed by 64 | Submission Open

Keywords: leukemia predisposition; germline variants; inherited syndromes; myelodysplastic syndrome (MDS); acute myeloid leukemia (AML); precision medicine

(This special issue belongs to the Section Molecular Cancer Biology)

The Next Cutting-Edge Technologies in Abdominal Solid Tumor Treatment

edited by Jerome Canady, Saravana R.K. Murthy, Aviram Nissan and

Michael Keidar

submission deadline 20 Jun 2026 | Viewed by 51 | Submission Open

Keywords: multi-visceral surgical resection for complex advanced gastrointestinal tumors; cytoreductive surgery; colon and gynecological cancers; pancreatic cancer; cold atmospheric plasma (CAP); robotic AI CAP surgical delivery systems; targeted immunotherapies; irreversible electroporation; HIPEC (hyperthermic intraperitoneal chemotherapy); PIPAC (pressurized intraperitoneal aerosol chemotherapy)

(This special issue belongs to the Section Methods and Technologies Development)

Decoding and Remodeling the Suppressive Tumor Immune Microenvironment in Head and Neck Cancer

edited by Andrew G. Sikora and Jennifer L. Anderson

submission deadline 20 Jun 2026 | Viewed by 28 | Submission Open

Keywords: tumor immune microenvironment (TIME); cancer-mediated immunosuppression; myeloid cells; regulatory T cells; cytokines; anti-tumor immunity; immune modulation

(This special issue belongs to the Section Tumor Microenvironment)

Displaying special issue 701-750 on page 15 of 24.

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