Brain Metastases: From Mechanisms to Treatment
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Metastasis".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 567
Special Issue Editors
Interests: drug delivery system to facilitate brain cancer-targeted molecular imaging diagnosis and imaging-guided drug delivery; novel nanoparticle-immunotherapy system to elicit anticancer immunity
Special Issue Information
Dear Colleagues,
Brain metastasis is the most common intracranial malignancy in adults. The current standard of care for brain metastasis includes surgical resection, stereotactic radiosurgery (SRS) and/or whole brain radiotherapy (WBRT). However, the prognosis for patients with brain metastasis is extremely poor, with a median survival of 8 to 16 months.
We are putting together a Special Issue of Cancers focusing on brain metastasis, which we hope will include recent advances in understanding mechanisms that underlie the development of brain metastasis and its tumor microenvironment (TME), such as the blood–tumor barrier (BTB), and in seeking new disease-specific biomarkers and novel treatment and combinatory treatment. We welcome contributions of both preclinical and clinical studies, as review articles or original research papers, on this clinically significant topic.
Prof. Dr. Dawen Zhao
Prof. Dr. Michael Chan
Guest Editors
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Keywords
- brain metastasis
- the tumor microenvironment
- blood–tumor barrier
- novel biomarkers and therapeutics
- radiation therapy
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