Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into Autacoids in Disease
edited by
submission deadline 31 Dec 2024 | Viewed by 292 | Submission Open
Keywords: angiotensin; bradykinin; endothelin; prostaglandins; thromboxanes; leukotrienes; serotonin; histamine; angiotensin-converting enzyme; angiotensin receptor; renin; kininogen; kallikrein; cyclooxygenase; phospholipase A2
(This special issue belongs to the Section Molecular Medicine)
State-of-the-Art Protein X-ray Crystallography
edited by Wu-Pei Su and
submission deadline 31 Dec 2024 | Viewed by 289 | Submission Open
Keywords: ab initio phasing methods; X-ray crystallography; protein structural determination; image reconstruction from Fourier amplitudes; iterative projection algorithms; phasing with deep learning methods
(This special issue belongs to the Section Molecular Structure and Dynamics)
Molecular and Biochemical Mechanisms of Age-Related Macular Degeneration, Neuroophthalmological Diseases and Uveitis
edited by
submission deadline 31 Dec 2024 | Viewed by 286 | Submission Open
Keywords: retina; neovascularization; age-related macular degeneration; uveal tissue; neuro-ocular diseases
(This special issue belongs to the Section Molecular Medicine)
Molecular Biomarkers in Cardiology 2024
edited by
submission deadline 31 Dec 2024 | Viewed by 265 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pathology and histology; carotid plaques and histology; endothelium and endothelial dysfunction; veins diseases; arrhythmias; heart
(This special issue belongs to the Section Molecular Biomarkers)
The Role of Oxidative Stress in Ovarian Cancer submission deadline 31 Dec 2024 | Viewed by 263 | Submission Open
Keywords: ovarian cancer; reactive oxygen species (ROS); metastasis; antioxidant; oxidative stress; chemotherapeutic resistance; inflammation
(This special issue belongs to the Section Molecular Medicine)
Barrier Formation and Homeostasis in the Vertebrate Brain
edited by , and
submission deadline 31 Dec 2024 | Viewed by 263 | Submission Open
Keywords: brain endothelial cell; pericytes; choroid plexus; retina; lymphatic; blood; astrocytes; oligodendrocytes; brain ventricle; microglia
(This special issue belongs to the Section Cellular Biochemistry)
The Role of MDM2 in Tumor Biology and Cancer Therapy submission deadline 31 Dec 2024 | Viewed by 260 | Submission Open
Keywords: MDM2; p53; targeted therapy; imunotherapy; drug resistance
(This special issue belongs to the Section Molecular Genetics)
Antitumor Agents from Natural Sources 2024 submission deadline 31 Dec 2024 | Viewed by 258 | Submission Open
Keywords: antitumor agents; natural sources; cancer prevention and therapy
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Recent Advances in Adduct Science
edited by Yukari Totsuka and Haruhiko Sugimura
submission deadline 31 Dec 2024 | Viewed by 254 | Submission Open
Keywords: adductomics; protein- or nucleic acid-adducts; biomarkers; exposome; genomic mutations; disease etiology; preventive strategies; drug discovery; risk assessment
Molecular Effects of Environmental Pollutants on Health of Human, Animals and Plants 2.0
edited by
submission deadline 31 Dec 2024 | Viewed by 252 | Submission Open
Keywords: health damage; reproductive health; environmental pollution; epigenetics; human; animals and plants
(This special issue belongs to the Section Natural and Bio-derived Molecules)
The Endoplasmic Reticulum Stress in Yeast and Fungal Cells
edited by
submission deadline 31 Dec 2024 | Viewed by 237 | Submission Open
Keywords: unfolded protein response; yeast; fungi; endoplasmic reticulum; protein production
(This special issue belongs to the Section Molecular Biology)
The Role of Non-coding RNAs in Health and Disease submission deadline 31 Dec 2024 | Viewed by 226 | Submission Open
Keywords: non-coding RNA; microRNA (miRNA); long noncoding RNA (lncRNA); circular RNA (circRNA); gene expression regulation; epigenetic modifications
(This special issue belongs to the Section Molecular Genetics)
Regeneration of Annelids: From Reorganization of Lost Body Parts to Cellular and Molecular Biological Background
edited by
submission deadline 31 Dec 2024 | Viewed by 219 | Submission Open
Keywords: regeneration; body plan; dedifferentiation; stem cells; morphallaxis; epimorphosis; neuro-immune interactions
(This special issue belongs to the Section Cellular Biochemistry)
Combination Therapies Involving MicroRNA Modulation: Synergistic Approaches for Enhanced Anticancer Effects submission deadline 31 Dec 2024 | Viewed by 210 | Submission Open
Keywords: microRNA (miRNA); targeted therapy; cancer
Novel Antimicrobial Strategies for Animal Health submission deadline 31 Dec 2024 | Viewed by 208 | Submission Open
Keywords: antimicrobial alternatives; antimicrobial resistance; animal health; infectious disease
(This special issue belongs to the Section Molecular Medicine)
The Development of Translational Cancer Research: In Honor of a Pioneering Professor, Ulrik Ringborg
edited by Ingemar Ernberg and Stephan Mielke
submission deadline 31 Dec 2024 | Viewed by 193 | Submission Open
Keywords: translational cancer research; tumor cell biology; precision cancer medicine
(This special issue belongs to the Section Molecular Medicine)
Bioinspired and Biomimicking Materials for Biomedical Applications: Second Edition
edited by
submission deadline 31 Dec 2024 | Viewed by 192 | Submission Open
Keywords: biomedical and biological imaging; biophotonics; biosensors; cell-based therapy; delivery systems; theranostics
Applications of NMR Spectroscopy in Structure-Based Drug Discovery
edited by Alexander L. Breeze and Reto Walser
submission deadline 31 Dec 2024 | Viewed by 188 | Submission Open
Keywords: NMR; structural biology; structure-based drug discovery; fragment screening; lead generation
(This special issue belongs to the Section Molecular Structure and Dynamics)
Peptide and Metabolite Self-Assembly: Physiology, Pathology, Biomaterials and Their Biomedical Applications
edited by and
submission deadline 31 Dec 2024 | Viewed by 182 | Submission Open
Keywords: peptide and metabolite; self-assembly; physiology and pathology; biomaterials; biomedicine
(This special issue belongs to the Section Molecular Structure and Dynamics)
Role of Glutathione Peroxidase in Health and Disease
edited by R Steve Esworthy
submission deadline 31 Dec 2024 | Viewed by 181 | Submission Open
Keywords: GPX1; GPX2; GPX3; GPX4; GPX5; GPX6; GPX7; GPX8; selenium; cancer; pathology
(This special issue belongs to the Section Molecular Medicine)
Transcription Factor E2F in Normal and Cancer Cells
edited by
submission deadline 31 Dec 2024 | Viewed by 181 | Submission Open
Keywords: E2F; RB; p53; cancer; tumor suppression
(This special issue belongs to the Section Biological Factors)
Alcohol-Related Organ Damage: Mechanisms, Outcomes, and Treatment Modalities submission deadline 31 Dec 2024 | Viewed by 180 | Submission Open
Keywords: alcoholic liver disease (ALD); steatohepatitis; fibrosis; cirhosis; parenhymal and non-parenhymal liver cells; brain; gut; lungs; immune responses; oxidative stress; methylation; viral infections; post-translational protein modifications; treatment of ALD
(This special issue belongs to the Section Molecular Medicine)
Biomolecules from Natural Products: Anti-inflammatory and Anti-allergic Activities: 2nd Edition
edited by
submission deadline 31 Dec 2024 | Viewed by 165 | Submission Open
Keywords: anti-inflammation; anti-allergic; natural product; anti-aging
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Tumour Suppressor Genes: The Guardians of Cell Integrity
edited by
submission deadline 31 Dec 2024 | Viewed by 162 | Submission Open
Keywords: cell cycle; cell growth; cell integrity; cell proliferation; DNA damage; genome integrity; protein homeostasis; migration; invasion; metastasis; apoptosis; autophagy
(This special issue belongs to the Section Molecular Biology)
Protein Misfolding Diseases: Molecular Mechanisms and Therapeutic Strategies
edited by Priyanka Joshi and Michele Perni
submission deadline 31 Dec 2024 | Viewed by 154 | Submission Open
Keywords: protein aggregation; protein misfolding; biomolecular condensation; chemical kinetics; cellular homeostasis; small molecules; antibody therapeutics; drug discovery; neurodegeneration; neurodegenerative diseases
(This special issue belongs to the Section Molecular Structure and Dynamics)
Molecular Mechanisms in New Strategies for Longevity
edited by
submission deadline 31 Dec 2024 | Viewed by 123 | Submission Open
Keywords: longevity; atherosclerosis; lipids; exercise; foods
Elucidating the Roles of Chromatin in Genomic Processes
edited by and Meijun Liu
submission deadline 31 Dec 2024 | Viewed by 119 | Submission Open
Keywords: nucleosome positioning and occupancy; histone modifications; histone variants; nucleosome chaperones; nucleosome remodelers; insulator proteins; CTCF and cohesin; cis-regulatory elements; 3D genome structure; chromatin dynamics
Prebiotics and Probiotics in Health and Disease: Looking at the Future submission deadline 7 Jan 2025 | 1 articles | Viewed by 1188 | Submission Open
Keywords: probiotics; live biotherapeutic product (LBP); next-generation probiotic (NGP); prebiotic; synbiotic/symbiotic; pharmabiotics; post-biotics; paraprobiotic/ghost probiotics/inactivated probiotics; probioceuticals/probiotaceuticals; biogenic; gut balance; gut– brain axis; vaginal homeostasis; vaginal microbiota modification or augmentation; oral microbiota; skin microbiota; new therapeutic approaches using bacteria; psychobiotics
(This special issue belongs to the Section Molecular Medicine)
Zinc in Health and Disease Conditions: 2nd Edition
edited by
submission deadline 10 Jan 2025 | 5 articles | Viewed by 6059 | Submission Open
Keywords: zinc; physiology; disease; regulation/modulation; function; pathology
(This special issue belongs to the Section Molecular Medicine)
Biosynthesis and Function of Thyroid Hormones
edited by and Eva K. Wirth
submission deadline 10 Jan 2025 | Viewed by 193 | Submission Open
Keywords: thyroid gland; thyroid follicle; TH release; iodide; deiodinase; TH transmembrane transport; TH receptors; intracellular TH binding proteins; thyroglobulin; sodium– iodide symporter; thyroperoxidase; dual oxidase; thyroid-relevant trace elements
(This special issue belongs to the Section Biological Factors)
Extracellular Vesicles as Biomarkers of Diseases submission deadline 15 Jan 2025 | 6 articles | Viewed by 8293 | Submission Open
Keywords: extracellular vesicles; metabolic syndrome; cancer; cardiovascular diseases; neurodegenerative diseases; biomarkers
(This special issue belongs to the Section Molecular Biomarkers)
The Value of Natural Compounds as Therapeutic Agents: 2nd Edition submission deadline 15 Jan 2025 | 4 articles | Viewed by 6632 | Submission Open
Keywords: natural compound; acute and chronic conditions; cell proliferation; cell death; cell differentiation
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Learn from Machine Learning: The Identification of Biomarkers and Therapeutic Targets in Neurodegeneration
edited by and
submission deadline 15 Jan 2025 | 2 articles | Viewed by 4165 | Submission Open
Keywords: machine learning; neurodegeneration; biomarkers; therapeutic targets; data mining
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms of Human Skin Aging
edited by
submission deadline 15 Jan 2025 | 3 articles | Viewed by 3841 | Submission Open
Keywords: skin aging; UV; extracellular matrix; fibroblast; prevention
(This special issue belongs to the Section Molecular Medicine)
Circular RNAs: Functions, Applications and Prospects: 2nd Edition
edited by and Feiya Li
submission deadline 15 Jan 2025 | 2 articles | Viewed by 3453 | Submission Open
Keywords: circular RNAs; circRNA; function; application; disease
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Cellular and Molecular Biology of Neurodevelopment
edited by
submission deadline 15 Jan 2025 | Viewed by 123 | Submission Open
Keywords: neural stem cells; neuroblasts; neurons; glia; microglia; molecular pathways; genes; mutations; pharmacology; toxicology; neurodevelopment; neurodevelopmental disorders
(This special issue belongs to the Section Molecular Biology)
Sterol Biosynthesis and Function in Organisms
edited by Hubert Schaller
submission deadline 20 Jan 2025 | 5 articles | Viewed by 5940 | Submission Open
Keywords: sterol; biosynthesis; function; organisms
(This special issue belongs to the Section Molecular Biology)
Physiological and Pathological Functions of Crystallins
edited by and John Clark
submission deadline 20 Jan 2025 | 1 articles | Viewed by 2095 | Submission Open
Keywords: crystallin; small heat shock protein chaperone; transparency; phase separation; aging; age related disease; cataract; cancer; schizophrenia; fertility
(This special issue belongs to the Section Biomacromolecules: Proteins)
Immune Responses in Type 1 Diabetes
edited by and Sally C. Kent
submission deadline 20 Jan 2025 | Viewed by 484 | Submission Open
Keywords: type 1 diabetes; insulitis; immune response
(This special issue belongs to the Section Molecular Biology)
Synaptogenesis, Synaptic Plasticity and Brain Disorders
edited by Rubén Deogracias
submission deadline 20 Jan 2025 | Viewed by 231 | Submission Open
Keywords: synaptic plasticity; neuron; brain disorders; brain damage
(This special issue belongs to the Section Molecular Biology)
Structural Proteomics–Structural Biology Led by Advancements in Mass Spectrometry Techniques
edited by , Corie Ralston and
submission deadline 20 Jan 2025 | Viewed by 117 | Submission Open
Keywords: hydroxyl radical protein footprinting MS (XFP; FPOP); hydrogen/deuterium exchange MS (HDX-MS); cross-linking MS (XL-MS); covalent labeling MS; top-down MS; native MS
(This special issue belongs to the Section Bioinformatics and Systems Biology)
More than Just Adhesion: Recognition Molecules, a Theme Issue Honoring Professor Melitta Schachner
edited by
submission deadline 25 Jan 2025 | 1 articles | Viewed by 2515 | Submission Open
Keywords: cell adhesion molecules; extracellular matrix; glycans; nervous system regeneration; nervous system development
(This special issue belongs to the Section Biological Factors)
Biogenic Amines, Their Receptors and Transporters in Health and Disease: Commemorative Issue in Honor of Professor Marc G. Caron (1946–2022)
edited by , , Jean Martin Beaulieu and Stephen S.G. Ferguson
submission deadline 31 Jan 2025 | 14 articles | Viewed by 33041 | Submission Open
Keywords: dopamine; serotonin; norepinephrine; epinephrine; histamine; trace amines; beta-phenylethylamine; GPCR; TAAR
(This special issue belongs to the Section Biological Factors)
Novel Materials for Biomedical Applications: 2nd Edition submission deadline 31 Jan 2025 | 8 articles | Viewed by 15365 | Submission Open
Keywords: micro-/nanocarriers; synthesis or conjugation of biomaterials; drug delivery; targeted therapy/immunotherapy for combinatorial treatment; regenerative medicine/tissue engineering
(This special issue belongs to the Section Biological and Bio- Materials)
Recent Advances in Neurological Diseases
edited by Sara Carpi, and
submission deadline 31 Jan 2025 | 5 articles | Viewed by 8149 | Submission Open
Keywords: neurological disorders; neurodegeneration; neuroinflammation; myelin damage; developmental disorders; epilepsy; neurodegenerative rare diseases; neuromuscular diseases; lipid storage diseases; psychiatric diseases
(This special issue belongs to the Section Molecular Medicine)
Cellular and Molecular Mechanisms of Endometriosis
edited by , Alessandra Andrisani and Chiara Sabbadin
submission deadline 31 Jan 2025 | 4 articles | Viewed by 6825 | Submission Open
Keywords: endocrine dysfunction in endometriosis; glycosylphosphatidylinositols (GPIs) and GPI-anchored proteins; oxidative stress markers (glutathione; carbonic anhydrase; etc.); endometriosis and deep endometriosis; endometriosis-related immune system
(This special issue belongs to the Section Molecular Biology)
The Structure and Function of Proteins, Lipids and Nucleic Acids
edited by
submission deadline 31 Jan 2025 | 5 articles | Viewed by 6525 | Submission Open
(This special issue belongs to the Section Molecular Structure and Dynamics)
NMDA Receptor in Health and Diseases: 2nd Edition
edited by
submission deadline 31 Jan 2025 | 4 articles | Viewed by 6428 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Hyaluronic Acid and Proteoglycans: Basic and Biomedical Applications
edited by
submission deadline 31 Jan 2025 | 4 articles | Viewed by 5829 | Submission Open
Keywords: hyaluronic acid; proteoglycans; GAGs; extracellular matrix; hyaluronic acid and proteoglycans in disease; cancer; inflammation; angiogenesis; vascular homeostasis and damage; arthritis and arthrosis; glycobiology
(This special issue belongs to the Section Biomacromolecules: Carbohydrates)
Inositol Phosphates in Health and Disease, 2nd Edition
edited by and
submission deadline 31 Jan 2025 | 4 articles | Viewed by 4898 | Submission Open
Keywords: inositol polyphosphates (IPs); IP6; inositol pyrophosphate (PP-Ips); signal transduction; energy metabolism; anticancer activity; PCOS; metabolic diseases; pathological calcification; neuropsychiatric disease
(This special issue belongs to the Section Molecular Medicine)
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