Metabolic Inflammation and Insulin Resistance in Obesity
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 336
Special Issue Editor
Special Issue Information
Dear Colleagues,
Obesity remains one of the most urgent public health challenges facing society today, especially in developed countries. Both obesity and its related conditions impose substantial economic and workforce burdens on healthcare systems worldwide. Over recent decades, research has increasingly demonstrated that obesity contributes not only to systemic insulin resistance but also to chronic, low-grade inflammation. This obesity-associated inflammation is thought to be primarily driven by the remodeling and redistribution of adipose tissue. Additionally, the complex interplay between adipose cells and immune cells in this process indicates a multifactorial mechanism that requires further investigation to fully understand the underlying inflammatory pathways.
We are pleased to introduce our Special Issue, “Metabolic Inflammation and Insulin Resistance in Obesity,” which aims to showcase novel research into the molecular mechanisms of obesity-related inflammation—its origins, progression, and potential therapeutic interventions. We encourage submissions that incorporate animal models or clinical studies, as these provide valuable insights with translational relevance. Through this issue, we hope to deepen understanding in this area and help guide future research directions.
While obesity is a major driver of metabolic inflammation, it is important to acknowledge that other factors, such as stress, aging, and gut dysbiosis, also play significant roles. We hope our future Special Issues will provide more opportunities to explore these related areas.
Dr. Bingxian Xie
Guest Editor
Manuscript Submission Information
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Keywords
- obesity-linked inflammation
- insulin resistance
- adipose tissue
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