New Insights into Stem Cell-Derived Exosomes in Human Health and Disease
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 25
Special Issue Editor
Interests: medical biology; tissue engineering; genetics and clinical genetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, stem cell-derived exosomes have emerged as potent mediators of intercellular communication, offering novel therapeutic and diagnostic possibilities across a broad spectrum of diseases. These nanosized extracellular vesicles, enriched with proteins, lipids, and nucleic acids, closely reflect their parent stem cells’ physiological state and regenerative potential. Unlike cell-based therapies, exosomes offer a cell-free approach that minimizes immunogenicity and tumorigenicity while preserving the ability to modulate immune responses, promote tissue repair, and influence disease progression. As our understanding of their biogenesis, cargo sorting mechanisms, and functional roles deepens, stem cell-derived exosomes are increasingly recognized for their translational potential in regenerative medicine, oncology, neurology, and immunology. This Special Issue highlights the latest advances in biology and the application of exosomes derived from various stem cell sources. We welcome contributions exploring their roles in health and disease, innovative isolation and characterization methods, and strategies to enhance their therapeutic efficacy. By gathering cutting-edge research and expert perspectives, this Issue seeks to provide a comprehensive overview of the field and identify new directions for clinical translation and biomedical innovation.
Dr. Lubos Danisovic
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- stem cells
- exosomes
- regenerative medicine
- diagnostics
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.