Defects in the Transport Mechanism of Membrane Proteins and Related Diseases, 2nd Edition
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 99
Special Issue Editor
Interests: structure/function relationship; transport mechanism; mitochondrial transport proteins; mitochondrial carrier diseases; mitochondrial carrier identification; design, synthesis and biological evaluation of new drugs against neurodegenerative diseases
Special Issue Information
Dear Colleagues,
Following a very successful first run, we are pleased to announce the launch of the second edition of a Special Issue on ‘Defects in the Transport Mechanism of Membrane Proteins and Related Diseases’.
Membrane transport proteins play crucial roles across biological membranes and participate in cell physiology, metabolism and signaling, maintaining cellular homeostasis, and permitting the translocation of many classes of metabolites (i.e., sugar, amino acids, lipids, vitamins, inorganic ions and others). These proteins are essential for cellular functions ensuring cell survival in response to frequent stimuli of intracellular or environmental stress. Indeed, the transport mechanism exerted by membrane transport proteins, generating concentration gradients via active transport mechanisms, passive diffusion and ion channels, contributes to the regulation of biochemical pathways through correct cellular concentrations of substrates and products. Therefore, genetic mutations or the impairment of transport systems would turn out in defects in the transport mechanism with changes in the expression, activity and structure of proteins, which are manifested in different groups of neurodegenerative and metabolic diseases.
Hence, the purpose of this Special Issue “Defects in the Transport Mechanism of Membrane Proteins and Related Diseases" is to integrate current knowledge regarding physiological functions and the mechanisms of transport of a wide group of membrane transport proteins underlying their involvements in the initiation and progression of many diseases. Research papers and review manuscripts depicting a special focus on membrane transporters are invited for submission. Short communications will also be taken into consideration.
Dr. Daniela Valeria Miniero
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- function, structure and folding of membrane transport proteins
- pathological mutations
- mechanism of transport
- neurological and metabolic disease
- transport of nanoparticles
- organelle membranes
- cellular function and signaling
- bioenergetics
- neuroinflammation
- nanoformulations for drug targets
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