Special Issue "Challenges in Glycan, Glycoprotein and Proteoglycan Research"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (31 May 2015).
In the past decades Glycoscience has evolved tremendously. The progress that has been made in the analytical and synthetic aspects is spectacular. The introduction of high resolution NMR spectroscopy and Mass spectrometry has enabled the unravelling of the structure of glycans derived from glycoconjugates like glycoproteins, proteoglycans and glycolipids as well as of oligo- and polysaccharides. Improvements in the synthetic procedures, e.g., the development of solid state synthesis and of oligosaccharide synthesizers have rendered the synthesis of complex glycans possible in a reasonable period of time. Intriguing are the roles glycans can play at the molecular level in a large diversity of biological processes like normal and abnormal cell growth and development, recognition and interaction phenomena, adhesion of pathogens.
The biological features imply that the borders with (micro)biology, medicine, immunology, vaccines etc. have definitively been crossed. Many new challenges are waiting in the field.
To illustrate for the readers of “Biomolecules” the importance of Glycoscience as a multidisciplinary field of research, this special issue is intended to show the various aspects, possibilities, applications and challenges of glycans and related compounds.
We look forward to reading your contributions,
Prof. Dr. Hans Vliegenthart
Manuscript Submission Information
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