Liver Cancer: Molecular and Translational Insights of Carcinogenesis and Treatments
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 22
Special Issue Editor
Interests: hepatocellular carcinoma; primary liver cancer; precancerous conditions; carcinogenesis; surgical pathology; biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Liver cancer is one of the most prevalent malignancies and a leading cause of cancer-related mortality worldwide. The two main subtypes, hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), pose significant clinical challenges. Despite recent advances in treatment, such as immune checkpoint inhibitors and targeted therapies, the overall prognosis remains poor. To improve clinical outcomes and advance personalized medicine, a more comprehensive understanding of the molecular and cellular mechanisms driving hepatic carcinogenesis is needed, along with the identification of robust diagnostic, prognostic, and predictive biomarkers. This Special Issue invites original research, reviews, and translational studies that explore the molecular and translational aspects of liver cancer. Topics of interest include the molecular and cellular pathogenesis of HCC and ICC, biomarker identification and validation, novel therapeutic targets, advancements in pathology and molecular diagnostics, and innovations in imaging techniques. In addition, submissions addressing the molecular and pathological characteristics of benign and premalignant hepatocellular and biliary tumors, as well as the updated histological and molecular classifications of HCC and ICC, are also welcome.
Prof. Dr. Joon Hyuk Choi
Guest Editor
Manuscript Submission Information
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Keywords
- liver cancer
- hepatocellular carcinoma
- intrahepatic cholangiocarcinoma
- carcinogenesis
- premalignant lesions
- diagnosis
- pathology
- treatment
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