Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ferroptosis: Mechanisms and Human Disease
edited by Chan-Yen Kuo
submission deadline 15 Aug 2026 | 4 articles | Viewed by 8438 | Submission Open
Keywords: ferroptosis; systemic diseases; inflammatory response; mitochondrial-dependent redox homeostasis; microenvironment
(This special issue belongs to the Section Cell Biology)
Changing Coral Reef Biodiversity and Function in the Anthropocene
edited by
submission deadline 15 Aug 2026 | Viewed by 378 | Submission Open
Keywords: anthropogenic stressors; coral reefs; climate change; biodiversity loss; marine conservation; ecological adaptation; ecosystem function; resilience
(This special issue belongs to the Section Marine and Freshwater Biology)
Role of CARD9 in Health and Diseases
edited by Zuberwasim Sayyad and Nikhil Sharma
submission deadline 15 Aug 2026 | Viewed by 134 | Submission Open
Keywords: CARD9; innate immunity; pattern recognition receptors; autophagy; apoptosis; inflammasome; reactive oxygen species; post-translational modifications; gut microbiota; inflammation and cancer
Recent Advances in Angiogenesis and Vascular Development submission deadline 15 Aug 2026 | Viewed by 33 | Submission Open
Keywords: vasculogenesis; angiogenesis; vascular differentiation markers; endothelial-to-mesenchymal transition (EndMT); mechanotransduction; endothelial function; endothelial damage
(This special issue belongs to the Section Cell Biology)
The Role of Autophagy and Macrophages in Modulating Immune Responses in Atherosclerosis
edited by and Aatira Vijay
submission deadline 25 Aug 2026 | Viewed by 134 | Submission Open
Keywords: atherosclerosis; macrophages; autophagy; immune regulation; chronic inflammation; plaque stability; lipid metabolism; efferocytosis; immunometabolism
Population Genetics and Conservation of Amphibians and Reptiles
edited by
submission deadline 25 Aug 2026 | Viewed by 84 | Submission Open
Keywords: conservation genetics; local adaptation; genetic diversity; amphibian; reptile; environmental change
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Animal Models of Arthritis
edited by Nevena Arsenović-Ranin and Biljana Bufan
submission deadline 30 Aug 2026 | 4 articles | Viewed by 10795 | Submission Open
Keywords: animal models; rheumatoid arthritis; osteoarthritis; inflammation; immunopathology; pathological features; joints; treatment; drug screening; traditional medicine
(This special issue belongs to the Section Medical Biology)
Young Researchers in Neuroscience
edited by Yansheng Du
submission deadline 31 Aug 2026 | 4 articles | Viewed by 34482 | Submission Open
Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology
(This special issue belongs to the Section Neuroscience)
Bone Cell Biology
edited by Yohei Abe and
submission deadline 31 Aug 2026 | 7 articles | Viewed by 17967 | Submission Open
Keywords: osteoclast; osteoblast; osteocyte; bone density; macrophage; RANK; transcription factor; cell signaling
(This special issue belongs to the Section Cell Biology)
Biology, Ecology and Management of Harmful Algae
edited by Paul V. Zimba and
submission deadline 31 Aug 2026 | 7 articles | Viewed by 9122 | Submission Open
Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources
Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease submission deadline 31 Aug 2026 | 2 articles | Viewed by 8691 | Submission Open
Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle
Lipid Metabolism in Plant Growth and Development
edited by Xiaohong Yu and Yingqi Cai
submission deadline 31 Aug 2026 | 2 articles | Viewed by 4307 | Submission Open
Keywords: lipid metabolism; lipid engineering; plant growth; plant development; lipid biosynthesis; lipid signaling; lipid transport; membrane structure; energy storage; plant– microbe interactions; stress response; nutrition value; cellular process
(This special issue belongs to the Section Plant Science)
Cellular and Molecular Biology of Liver Diseases
edited by Matthew McMillin
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1592 | Submission Open
Keywords: drug-induced liver injury; cholestasis; hepatitis; metabolic dysfunction-associated steatotic liver disease; alcohol-associated liver disease
(This special issue belongs to the Section Cell Biology)
Host–Microbiome–Environment Interactions in Domestic and Wild Animals
edited by and Cesar A. Meza-Herrera
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1358 | Submission Open
Keywords: animal microbiome; environmental microbiota; host– microbiota interactions; wildlife microbiology; livestock health and productivity; microbiome and conservation; One Health approach; gut microbiota dynamics; microbial ecology; microbiome and reproduction; habitat– host microbiome linkages; multi-omics integration
(This special issue belongs to the Section Microbiology)
Regenerative Biology: Regeneration After Spinal Cord and Peripheral Nerve Injury submission deadline 31 Aug 2026 | 1 articles | Viewed by 1304 | Submission Open
Keywords: neuronal regeneration; peripheral nerve repair; spinal cord injury; axonal growth; neuroplasticity; glial cells; molecular signaling pathways; stem cells in nerve regeneration; neuroinflammation; animal models of nerve injury
(This special issue belongs to the Section Neuroscience)
Advances in Leishmaniasis and Chagas Disease: Biology, Epidemiology, Treatment and Control (2nd Edition) submission deadline 31 Aug 2026 | 1 articles | Viewed by 709 | Submission Open
Keywords: leishmaniasis; Chagas disease; immunopathogeny; diagnosis; epidemiology; control; vaccine
Bone Mechanics: From Cells to Organs, to Function submission deadline 31 Aug 2026 | 1 articles | Viewed by 627 | Submission Open
Keywords: bone mechanics; bone remodeling; mechanotransduction; structural analysis; functional morphology; bioengineering
(This special issue belongs to the Section Physiology)
Microbiology and Metabolomics in Reproductive Biology submission deadline 31 Aug 2026 | Viewed by 362 | Submission Open
Keywords: maternal microbiome; metabolome; pregnancy outcomes; fetal development; biomarkers; immune function; metabolic health; disease prediction; therapeutic interventions; maternal and child health
(This special issue belongs to the Section Developmental and Reproductive Biology)
Sickle Cell Disease: Molecular Mechanisms, Pathogenesis and Therapies
edited by Chithra Palani
submission deadline 31 Aug 2026 | Viewed by 343 | Submission Open
Keywords: SCD; anemia; erythrocyte development; erythroid progenitors; CD34 cells; vaso-occlusion; pain crisis; hemolysis; oxidative stress; sickling; inflammation; ER stress; fetal hemoglobin; hematopoiesis; ischemia and tissue damage; organ damage; drug development; SCD diagnosis; gene therapy; cell therapy
(This special issue belongs to the Section Medical Biology)
Advances in Cardiac and Vascular Biology: From Mechanisms to Pathophysiology
edited by and
submission deadline 31 Aug 2026 | Viewed by 249 | Submission Open
Keywords: cardiovascular biology; molecular mechanisms; cellular signaling; epigenomic regulation; vascular remodeling; metabolic reprogramming; cardiac pathophysiology
(This special issue belongs to the Section Physiology)
Biophysics of Exposome: Molecular Mechanisms of Action
edited by and Madhavi K. Ganapathiraju
submission deadline 31 Aug 2026 | Viewed by 167 | Submission Open
Keywords: computational biology; systems biology; mass spectrometry; protein– ligand networks; protein– protein interaction networks; metabolomics; proteomics; surface plasmon resonance; protein structure prediction; molecular docking; target fishing; machine learning; artificial intelligence
Current Status and Future Perspectives on Lipid Biology and Beyond submission deadline 31 Aug 2026 | Viewed by 143 | Submission Open
Keywords: lipids; fatty acids (FAs); omega-3 (FA); omega-6 (FA); cancer; cell biology; oxylipins; oxidative stress; lipidomics; lipid nanoparticles; personalized lipid-based therapies
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Fruits and Seeds of Tropical Plants: Conservation of Species, Ecological Importance and Quality Valorization
edited by Edna Ursulino Alves and Silvanda De Melo Silva
submission deadline 31 Aug 2026 | 1 articles | Viewed by 130 | Submission Open
Keywords: climate change; nature conservation; biodiversity; plant propagation; postharvest quality; metabolic profile; orchard management and quality
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Energy Metabolism, Genetics and Development in Drosophila
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 93 | Submission Open
Keywords: Drosophila; energy metabolism; development; epigenetics; non-coding RNAs; metabolic disease; growth; signaling pathway
(This special issue belongs to the Section Bioinformatics)
Mitochondrial Genomics of Arthropods
edited by Renfu Shao
submission deadline 31 Aug 2026 | Viewed by 89 | Submission Open
Keywords: mitochondrial genome architecture; transcriptional dynamics; translational mechanisms; comparative genomics; molecular evolution; arthropod phylogenetics; systematics; evolutionary biology
(This special issue belongs to the Section Genetics and Genomics)
Research Progress on Metabolic Pathways in Neurodegenerative Diseases
edited by Ali H. Rafati
submission deadline 31 Aug 2026 | Viewed by 85 | Submission Open
Keywords: neurodegeneration; metabolic dysfunction; mitochondrial impairment; oxidative stress; glucose metabolism; lipid metabolism; autophagy; neuroinflammation; biomarkers; therapeutic targets
(This special issue belongs to the Section Neuroscience)
Novel Mechanisms and Biological Processes in Redox and Inflammatory Signaling
edited by Shengchen Wang and
submission deadline 31 Aug 2026 | Viewed by 54 | Submission Open
Keywords: redox; inflammatory; oxidative stress; antioxidant; anti-inflammatory; signaling pathways
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Biogenesis and Function of Centrioles, Centrosomes, and Primary Cilia in Health and Disease submission deadline 31 Aug 2026 | Viewed by 51 | Submission Open
Keywords: centriole; centrosome; cilia
(This special issue belongs to the Section Cell Biology)
Uncovering the Role of T Cells in Immune Homeostasis and Immune Tolerance
edited by
submission deadline 31 Aug 2026 | Viewed by 28 | Submission Open
Keywords: regulatory T cells; immune tolerance; FOXP3; cytokine; suppression
(This special issue belongs to the Section Cell Biology)
Biosynthesis of Metabolites from Microorganisms, or Microorganism-Host Interaction? (Volume II) submission deadline 1 Sep 2026 | 6 articles | Viewed by 17560 | Submission Open
Keywords: biosynthesis; biological activity; biosynthesis regulation; microbial metabolites; microbe– host reaction
(This special issue belongs to the Section Microbiology)
Viral Infections in Animals: Pathogenesis and Immunity
edited by
submission deadline 1 Sep 2026 | 1 articles | Viewed by 1645 | Submission Open
Keywords: virus– host interactions; antiviral immunity; mechanisms of viral pathogenesis
(This special issue belongs to the Section Immunology)
Latest Discoveries in Non-Model Organisms and Non-Translational Biology submission deadline 8 Sep 2026 | Viewed by 147 | Submission Open
Keywords: basic biological research; non-translational biology; non-clinical biology; fundamental science; non-model organisms; model organisms; scientific curiosity– driven research; biological diversity; experimental biology; theoretical biology
Feature Papers on Developmental and Reproductive Biology
edited by
submission deadline 15 Sep 2026 | 11 articles | Viewed by 26541 | Submission Open
Keywords: embryo/fetus development; reproductive biology; gametogenesis; differentiation; growth; homeostasis; regeneration; aging; cell cycle regulation; stem cells; organoids
(This special issue belongs to the Section Developmental and Reproductive Biology)
Molecular and Cellular Mechanisms of Neuroinflammation and Chronic Pain
edited by Mario Garcia-Dominguez
submission deadline 15 Sep 2026 | Viewed by 38 | Submission Open
Keywords: neuroinflammation; chronic pain; neuroimmune interactions; glial activation; cytokine signaling; synaptic plasticity; oxidative stress; epigenetic regulation; microglia and astrocytes; therapeutic targets
(This special issue belongs to the Section Neuroscience)
Plant Breeding: From Biology to Biotechnology
edited by Juwu Gong
submission deadline 30 Sep 2026 | 5 articles | Viewed by 8128 | Submission Open
Keywords: plant breeding; biotechnology; molecular marker-assisted selection; genetic engineering; genome editing; tissue culture; phenotype; genetics; omics
(This special issue belongs to the Section Biotechnology)
Signalling Pathways in Cancer and Disease submission deadline 30 Sep 2026 | 5 articles | Viewed by 5478 | Submission Open
Keywords: cancer; signalling; metastasis; tumorigenesis; cancer targeting
(This special issue belongs to the Section Cancer Biology)
Molecular Basis of Bone Homeostasis and Skeletal Diseases
edited by
submission deadline 30 Sep 2026 | 3 articles | Viewed by 5455 | Submission Open
Keywords: osteoclast; osteoblast; bone; skeletal disease; bone formation; bone resorption; osteoporosis; osteopetrosis; human genetics; mouse genetics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Research Advancements in Oral Biology
edited by and Nina Petrović
submission deadline 30 Sep 2026 | 2 articles | Viewed by 3255 | Submission Open
Keywords: oral biology; oral tissue regeneration; artificial intelligence (AI) in dentistry; genomics and proteomics in dentistry; dental research; salivary diagnostics
(This special issue belongs to the Section Medical Biology)
The Role of Innate Immunity in Organ Transplantation
edited by Todd V. Brennan
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1510 | Submission Open
Keywords: innate immunity; allograft rejection; transplantation; immune tolerance
(This special issue belongs to the Section Medical Biology)
Molecular Mechanisms of Cell Signal Transduction
edited by
submission deadline 30 Sep 2026 | Viewed by 483 | Submission Open
Keywords: molecular interactions in signaling; phosphorylation and signal propagation; post-translational modifications; cross-talk between signaling pathways; cellular response to extracellular stimuli; metabolic regulation and signaling; signaling in cancer progression; inflammatory signaling pathways; role of signaling in stem cell differentiation; innovative imaging techniques for signaling
(This special issue belongs to the Section Cell Biology)
Physiology and Ecology of Animal Parasites and Related Diseases
edited by Marcela K. Castelo
submission deadline 30 Sep 2026 | Viewed by 410 | Submission Open
Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change
(This special issue belongs to the Section Zoology)
More than a Shield: The Secret Functions of Epithelial Cells in Homeostasis and Infections
edited by and Na Zhao
submission deadline 30 Sep 2026 | Viewed by 241 | Submission Open
Keywords: epithelial diversity; signaling; homeostasis; immunity; infection; microbiome; inflammation; cytokines; antimicrobial peptides
(This special issue belongs to the Section Medical Biology)
Bone Physiology and Development
edited by , and Yohei Abe
submission deadline 30 Sep 2026 | Viewed by 112 | Submission Open
Keywords: osteology; osteogenesis; bone growth; bone physiology; bone morphology; bone pathology; bone imaging
(This special issue belongs to the Section Physiology)
Gut Microbiome in Health and Disease (3rd Edition)
edited by and
submission deadline 30 Sep 2026 | Viewed by 111 | Submission Open
Keywords: gut microbiota; ‘ gut– X’ axis; dysbiosis; food nutrition; metabolites; type 2 diabetes mellitus; gut health; immunity
(This special issue belongs to the Section Microbiology)
Molecular Mechanisms of Retina Development and Degeneration submission deadline 30 Sep 2026 | Viewed by 93 | Submission Open
Keywords: retina; retinal development; retinal degeneration; molecular mechanisms; signaling pathways; genetic regulation; epigenetics; neuronal and glial interactions; neuroinflammation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
The Molecular and Cellular Mechanisms of Lung Injury and Recovery
edited by Weiguo Chen, HongLong Ji and Ibra S. Fancher
submission deadline 30 Sep 2026 | Viewed by 87 | Submission Open
Keywords: acute lung injury; chronic lung injury; ARDS; fibrosis; allergy; mechanisms; therapy; infection; inflammation; endothelial barrier
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Pathogenic Mechanisms Involved in Development and Progression of ROS-Associated Diseases
edited by
submission deadline 30 Sep 2026 | Viewed by 55 | Submission Open
Keywords: Reactive Oxygen Species (ROS); oxidative stress; pathogenic mechanisms; disease progression; mitochondrial dysfunction; inflammation and immune regulation; redox biology; molecular signaling pathways; antioxidants and therapeutics; comparative medicine; One Health; translational research
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Innovative Approaches to Rice Crop Production Under Environmental Stresses submission deadline 30 Sep 2026 | Viewed by 52 | Submission Open
Keywords: abiotic stress; environmental stress response; stress adaptation; DNA damage and repair; functional genomics; plant physiology; biofortification
(This special issue belongs to the Section Genetics and Genomics)
Genetics and Epigenetics of Neurological Disorders submission deadline 30 Sep 2026 | Viewed by 24 | Submission Open
Keywords: neurological disorders; neurogenetics; genomics; epigenomics; DNA methylation; precision medicine
(This special issue belongs to the Section Neuroscience)
Ecological Interactions and Adaptive Strategies in Wildlife
edited by
submission deadline 30 Sep 2026 | Viewed by 22 | Submission Open
Keywords: biological pest control; predator– prey dynamics; avian reproductive ecology; evolutionary traits; human– wildlife coexistence; invasive species impacts; artificial nest ecology; ecosystem
(This special issue belongs to the Section Conservation Biology and Biodiversity)
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