Special Issues

Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Preventive and Therapeutic Strategies to Eradicate Biofilm Infections Based on New Antibacterial Compounds
edited by
submission deadline 20 Apr 2026 | Viewed by 189 | Submission Open
Keywords: antibacterial; biofilm; infection; innovation; microbiota
(This special issue belongs to the Section Antibiofilm Strategies)
Antimicrobial Resistance in the Era of Climate Change
edited by and Eleni Geladari
submission deadline 25 Apr 2026 | 4 articles | Viewed by 5691 | Submission Open
Keywords: climate change; extremes in temperature; antimicrobial resistance (AMR)
Artificial Intelligence and Antimicrobial Resistance: Innovation, Global Challenges and the Future of Healthcare submission deadline 30 Apr 2026 | 2 articles | Viewed by 14002 | Submission Open
Keywords: antimicrobial resistance; artificial intelligence; digital health; drug discovery; patient-centric care; therapeutic innovations
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
New Paradigms Concerning the Production of Antibiotics: Between Ecological Responsibility and Revalorization of Narrow Spectrums
edited by
submission deadline 30 Apr 2026 | 3 articles | Viewed by 10284 | Submission Open
Keywords: one health; environmental pollution; human health; antimicrobial production; livestock; antimicrobial resistance; antimicrobial stewardship
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Metal-Based Complexes as Novel Antimicrobial Strategies submission deadline 30 Apr 2026 | 1 articles | Viewed by 5337 | Submission Open
Keywords: antibiotics; metal-based complexes; antimicrobial resistance; antimicrobial therapy; drug design; bioinorganic; metallodrug; metallopharmaceutical
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antimicrobial Stewardship—from Projects to Standard of Care
edited by Gesche Först and Franky Buyle
submission deadline 30 Apr 2026 | 4 articles | Viewed by 3669 | Submission Open
Keywords: antimicrobial stewardship; antimicrobial use; antibiotics; implementation; efficacy; quality; antimicrobial prescribing
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Perspective on the Role of Farm Animals in the Transmission of Antimicrobial Resistance from a One Health Approach submission deadline 30 Apr 2026 | 2 articles | Viewed by 2956 | Submission Open
Keywords: antimicrobials use; farm animals; antimicrobial resistance; one health; antimicrobials; food safety; public health
(This special issue belongs to the Section Antibiotics in Animal Health)
Antibiotic Resistance in a One Health Context: Bridging Environmental, Agricultural, Nutritional, Veterinary, and Clinical Perspectives submission deadline 30 Apr 2026 | 2 articles | Viewed by 2709 | Submission Open
Keywords: antibiotic resistance; One Health; environmental microbiology; zoonotic pathogens; antimicrobial stewardship; resistance mechanisms; horizontal gene transfer; integrated surveillance; microbial ecology; public health
(This special issue belongs to the Section Antibiotics in Animal Health)
Prevalence, Treatment and Antibacterial Resistance of Urinary Tract Infections
edited by Alin Gabriel Mihu and
submission deadline 30 Apr 2026 | 1 articles | Viewed by 2593 | Submission Open
Keywords: urinary tract infections; UTI; antibiotic; antibacterial; resistance; uropathogens; recurrent UTI; Enterobacteriaceae; Escherichia coli  
Evidence in Antibiotic Mastitis Therapy submission deadline 30 Apr 2026 | 1 articles | Viewed by 2457 | Submission Open
Keywords: antibiotic mastitis treatment; targeted; selective; pathogens; mastitis history; new infections
(This special issue belongs to the Section Antibiotics in Animal Health)
Antimicrobial Peptides: An Emerging Hope in the Era of New Infections and Resistance, 2nd Edition
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1996 | Submission Open
Keywords: antimicrobial peptides; antimicrobial resistance; infectious diseases; antibacterial; antifungal; immunomodulatory properties; therapeutics; evolution
(This special issue belongs to the Section Antimicrobial Peptides)
Strategies for the Design of Hybrid-Based Antimicrobial Compounds
edited by , and
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1975 | Submission Open
Keywords: hybrid compounds; antimicrobial agents; antibacterial agents; antifungal activity; antiviral activity; in vitro evaluation; structure– activity relationship (SAR); bioactive molecules; nanoformulations; targeted drug delivery; pharmacological screening; clinical studies
(This special issue belongs to the Section Novel Antimicrobial Agents)
Epidemiology and Antimicrobial Dosing Regimens in Intensive Care Units
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1165 | Submission Open
Keywords: epidemiology; critical care; sepsis; empiric therapy; dosing; interactions; antibiotic resistance; therapeutic drug monitoring; pharmacokinetics/pharmacodynamics; renal insufficiency; renal replacement therapy
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Antimicrobial Resistance, Epidemiology, Clinical Impact and Molecular Characterization of Multidrug-Resistant ESKAPEE Pathogens
edited by and Viviana Manzulli
submission deadline 30 Apr 2026 | 1 articles | Viewed by 951 | Submission Open
Keywords: ESKAPEE; antimicrobial resistance; antibiotic resistance; multidrug-resistant pathogens; nosocomial infection; molecular mechanism
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antimicrobial Plant Peptides as Prototypes of New Antifungal Drugs submission deadline 30 Apr 2026 | 1 articles | Viewed by 511 | Submission Open
Keywords: fungal infections; fungal virulence factors; fungal resistance; plant antimicrobial peptides (AMPs); antifungal activity; prevention of fungal adhesion and biofilm formation; immunomodulatory properties; structure-activity relationships; peptide engineering
Fighting the Superbug Surge: Strategies in Antimicrobial Stewardship and Infection Control
edited by Sara Revolinski, Kristen Bresnehan and Lucas Schulz
submission deadline 30 Apr 2026 | 1 articles | Viewed by 335 | Submission Open
Keywords: antimicrobial stewardship; infection control; infection prevention; multidrug resistant organisms; antimicrobial resistance
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Design and Synthesis of Novel Antibiotics, 2nd Edition
edited by Kenneth Ikenna Onyedibe
submission deadline 30 Apr 2026 | Viewed by 175 | Submission Open
Keywords: drug discovery; antimicrobial modes of action; antimicrobial resistance; structural characterization; antimicrobial activity
(This special issue belongs to the Section Novel Antimicrobial Agents)
Metal-Based Antibiotics and Therapeutics submission deadline 30 Apr 2026 | Viewed by 170 | Submission Open
Keywords: biological inorganic chemistry; metallotherapeutics; metal-based antibiotics; antimicrobial compounds; antimicrobial resistance (AMR); antimicrobials materials or nanoparticles; active medical devices
(This special issue belongs to the Section Novel Antimicrobial Agents)
Distribution, Sources and Risks of Bacteria and Their Antimicrobial Resistance Genes in the Environment, 2nd Edition
edited by Filip Gamoń, and Suparna Mitra
submission deadline 30 Apr 2026 | Viewed by 147 | Submission Open
Keywords: antimicrobial resistance (AMR) and One Health; AMR dissemination in the environment; risk assessment of AMR in environmental reservoirs (agroecosystems); antibiotic-resistant pathogenic and resident bacteria; antibiotic-resistance gene (ARG) transfer; ARG quantification; AMR and food/feed chain; antibiotics in animals; agrochemicals; antibiotic residues
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antibiotic Therapies for Multidrug-Resistant Infections submission deadline 30 Apr 2026 | Viewed by 130 | Submission Open
Keywords: MDR; gram-negative infections; acinteobacter baumannii; stenotrophomonas maltophilia; KPC; MBL
Rapid Antifungal Susceptibility Testing and Diagnostics of Antifungal Resistance
edited by Valentina Salas
submission deadline 30 Apr 2026 | Viewed by 112 | Submission Open
Keywords: antifungal resistance; drug resistance mechanisms; multidrug resistance; intrinsic resistance and acquired resistance; new resistant opportunistic fungi
Advanced Nanomaterials and Bioinspired Strategies for Antimicrobial Applications
edited by , Gerson Nakazato and
submission deadline 30 Apr 2026 | Viewed by 111 | Submission Open
Keywords: antimicrobial nanomaterials; bioinspired materials; biomaterials engineering; antimicrobial resistance (AMR); nanostructured antimicrobials; bionanotechnology; green chemistry; antibacterial coatings
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antibiotic Use and the Emergence of Antibiotic Resistance in Clinical Settings, 2nd Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 108 | Submission Open
Keywords: antibiotic use; antibiotic resistance; clinical settings; clinical infections; mechanisms underlying the development of resistance
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antibiotic Susceptibility Testing Guides Clinical Treatment Decisions: From Empiric to Targeted Therapy
edited by , Simona Arientová and
submission deadline 30 Apr 2026 | Viewed by 100 | Submission Open
Keywords: antimicrobial susceptibility testing; antimicrobial resistance; empiric antimicrobial therapy; targeted antimicrobial therapy; clinical microbiology; infectious diseases; antimicrobial stewardship; infectious disease management; multidrug-resistant organisms
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Multidrug-Resistant Microorganisms: Overcoming the Challenges in Antibiotic Treatment
edited by Eleni E. Mylona and
submission deadline 30 Apr 2026 | Viewed by 97 | Submission Open
Keywords: multidrug-resistant; antibiotic treatment; MDR pathogens; therapeutic strategies
Pharmacokinetic and Antibiotic Dosing for Intensive Care Unit Patients, 2nd Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 84 | Submission Open
Keywords: antibiotics; pharmacokinetics– pharmacodynamics; therapeutic drug monitoring; population pharmacokinetics analysis; bacterial susceptibility
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Exploring Synthetic Organic Chemistry to Combat Pathogenic Infections submission deadline 30 Apr 2026 | Viewed by 77 | Submission Open
Keywords: synthetic organic chemistry; antimicrobial agents; structure– activity relationship (SAR); drug design; molecular docking; drug discovery
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antibiotics and Environment—Research and Development Toward the One Health Approach, 2nd Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 68 | Submission Open
Keywords: antimicrobial resistance (AMR); antimicrobials; water purification plant (WTP); wastewater treatment plant (WWTP); hospital wastewater; livestock environment; aquaculture farm environment; aquatic environment
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Plant-Derived Nanoantibiotics: Innovations and Applications submission deadline 30 Apr 2026 | Viewed by 65 | Submission Open
Keywords: nanotechnology; plant-derived antibiotics; nanoparticles; antimicrobial resistance; green synthesis; drug delivery; nano-formulations; bioactive compounds; nanoantibiotics
Healthcare-Associated Infections (HAIs): Prevention, Control and Surveillance, 2nd Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 51 | Submission Open
Keywords: healthcare-associated infections (HAIs); infection prevention and control; antimicrobial resistance; HAIs management and control; carbapenem resistant (CR) Enterobacterales; carbapenem resistant (CR) Acinetobacter baumannii
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial Treatment Challenges in Gastroenterology and Malignancy Associated Infections: Current Trends, Debates and Future Perspectives
edited by and Péter Birinyi
submission deadline 30 Apr 2026 | Viewed by 19 | Submission Open
Keywords: gastroenterology; oncology; antibiotic resistance; antimicrobial treatment
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antibiotics Use in Farms, 3rd Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 19 | Submission Open
Keywords: non-antibiotic; alternative therapeutic options (to antibiotics); alternative production strategies; vaccines; farm-sourced surveillance of antibiotic resistance; clonal lineages
(This special issue belongs to the Section Antibiotics in Animal Health)
Pathogenesis, Epidemiology and Antibiotic Resistance of Salmonella submission deadline 1 May 2026 | Viewed by 622 | Submission Open
Keywords: Salmonella; epidemiology; genomics; public health; antimicrobial resistance; One-Health approach
Antimicrobial Resistance and Infections in Animals
edited by
submission deadline 10 May 2026 | 7 articles | Viewed by 18719 | Submission Open
Keywords: antimicrobial resistance; mechanisms; humane and societal concerns; risk factors
(This special issue belongs to the Section Antibiotics in Animal Health)
Novel Antimicrobial Strategies to Combat Multidrug-Resistant (MDR) Gram-Negative Bacteria, 2nd Edition
edited by
submission deadline 10 May 2026 | 2 articles | Viewed by 2325 | Submission Open
Keywords: gram negative; antibiotic resistance; antiseptic resistance; multidrug resistant; extensively drug resistant; pandrug resistant; MDR; XDR; PDR; efflux pumps; mechanisms of resistance; beta-lactamase; outer membrane
Biotechnological Production of Novel Antimicrobials submission deadline 15 May 2026 | 1 articles | Viewed by 1588 | Submission Open
Keywords: antibiotic resistance; biotechnology; antimicrobial activity; disease outbreak; pathogens; microorganisms; genetic engineering; artificial intelligence; optimisation; biocontrol
A Themed Issue in Honor of Professor Helen Giamarellou—Outstanding Contributions in the Fields of Antimicrobial Resistance and Difficult-to-Treat Resistance Pathogens
edited by Konstantinos Pontikis
submission deadline 20 May 2026 | 6 articles | Viewed by 22773 | Submission Open
Keywords: antibiotic stewardship; nosocomial infections; infection control; epidemiology of resistance plus in vitro investigation of underlying resistance mechanisms; infections in the ICU; neutropenic host infections; indicated therapeutic approach of MDR and XDR gram-negative infections; pharmacokinetics/pharmacodynamics of newer antimicrobial agents
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Evidence-Based Pharmaceutical Care and Rational Antibiotic Use
edited by and Siyan Zhan
submission deadline 20 May 2026 | Viewed by 69 | Submission Open
Keywords: rational antibiotic use; bacterial resistance; medical institutions; optimization of antibiotic usage and dosages; prescription
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Innovative and Translational Antibiosis Approaches to Tackling Protozoan Parasites: Synergy, Drug Repurposing, Natural Products, Molecular Targets, and Therapeutic Design
edited by
submission deadline 30 May 2026 | Viewed by 153 | Submission Open
Keywords: drug repurposing for neglected tropical diseases; natural products with antiparasitic activity; synergistic drug combinations; molecular targets and mechanisms of action
Antibiotic Prescribing in Primary Dental Care—2nd Edition
edited by
submission deadline 30 May 2026 | Viewed by 151 | Submission Open
Keywords: primary dental care; antibiotic prescribing; rational drug prescribing; antibiotic stewardship
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial Stewardship in Neonatal Intensive Care
edited by Chiara Poggi
submission deadline 30 May 2026 | Viewed by 65 | Submission Open
Keywords: neonatal sepsis; early onset sepsis; late onset sepsis; preterm; antimicrobial stewardship; neonatal intensive care; molecular diagnosis; stopping rule; therapeutic drug monitoring; extended antimicrobial infusion; continuous antimicrobial infusion; microbiological surveillance
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antibiofilm Activity against Multidrug-Resistant Pathogens
edited by and Petar Knezevic
submission deadline 31 May 2026 | 7 articles | Viewed by 23707 | Submission Open
Keywords: biofilm; microbial drug resistance; antibiofilm agents; antibiofilm strategies; synergistic interactions
(This special issue belongs to the Section Antibiofilm Strategies)
Mechanism of Carbapenem Resistance in Enterobacteriaceae, Acinetobacter and Pseudomonas aeruginosa submission deadline 31 May 2026 | 5 articles | Viewed by 18290 | Submission Open
Keywords: gram-negative infections; mechanism of carbapenem resistance; molecular epidemiology; in vitro diagnostic tools; antimicrobial treatment; beta-lactam/beta lactamase inhibitors; cefiderocol
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Insights into Natural Antimicrobial Peptides submission deadline 31 May 2026 | 4 articles | Viewed by 15203 | Submission Open
Keywords: antibacterial host defense peptides; antibacterial mode of action; defensins; cathelicidins; insect antimicrobial peptides; plant antimicrobial peptides
(This special issue belongs to the Section Antimicrobial Peptides)
Antibiotic Residues, Antimicrobial Resistance and Intervention Strategies of Foodborne Pathogens, 2nd Edition
edited by and
submission deadline 31 May 2026 | 3 articles | Viewed by 10181 | Submission Open
Keywords: antibiotic residues; antibiotic resistance genes; antimicrobial resistance; food safety; foodborne pathogen; intervention strategies; one health
Molecular Epidemiology and Mechanisms of Carbapenem Resistance in Clinical Gram-Negative Bacteria
edited by and José Manuel Ortiz De La Rosa
submission deadline 31 May 2026 | 4 articles | Viewed by 7823 | Submission Open
Keywords: carbapenem resistance; Enterobacterales; Pseudomonas aeruginosa; Acinetobacter baumannii; molecular epidemiology
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Emerging Topics in Clostridioides difficile Infection: A One Health Problem
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 7362 | Submission Open
Keywords: clostridium difficile infection (CDI); antimicrobial resistance (AMR); antimicrobial prescribing; one health; laboratory studies
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Revolutionizing Infection Treatment: Cutting-Edge Approaches in Antimicrobial Stewardship
edited by Jacob Myles Keck and
submission deadline 31 May 2026 | 4 articles | Viewed by 4791 | Submission Open
Keywords: antimicrobial stewardship; antimicrobial resistance; infection treatment optimization; rapid diagnostics; technology in healthcare
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Optimizing Antimicrobial Therapy in NICU Settings: Strategies and Implications submission deadline 31 May 2026 | 2 articles | Viewed by 4507 | Submission Open
Keywords: neonatal ICU; antimicrobial stewardship; antimicrobial resistance; neonatal sepsis; biomarkers
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Fungal Metabolites and Synthetic Derivatives: Antimicrobial Properties Toward Microbial Pathogens submission deadline 31 May 2026 | 2 articles | Viewed by 2957 | Submission Open
Keywords: antimicrobial resistance; fungal metabolites; synthetic derivatives; antifungal agents; bioactive compounds
(This special issue belongs to the Section Fungi and Their Metabolites)
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