Candida auris and Antifungal Resistance: Epidemiology, Detection, and Therapeutic Challenges
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Mechanism and Evolution of Antibiotic Resistance".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 7
Special Issue Editor
Interests: Candida auris; antifungal resistance; antifungal susceptibility testing; molecular diagnostics; nosocomial fungal infections; MALDI-TOF MS; infection control; multidrug resistance
Special Issue Information
Dear Colleagues,
Candida auris has emerged over the past decade as a major global public health concern due to its rapid spread, multidrug resistance, and ability to cause nosocomial outbreaks, particularly in intensive care units. Unlike other Candida species, C. auris demonstrates remarkable persistence in hospital environments and is associated with high mortality rates in invasive infections. One of the most critical challenges posed by C. auris is its frequent resistance to multiple antifungal classes, including azoles, echinocandins, and polyenes.
This Special Issue aims to provide a comprehensive overview of Candida auris, focussing on its epidemiology, antifungal resistance mechanisms, phenotypic and molecular diagnostic approaches, antifungal susceptibility testing, and challenges related to method standardisation. Topics of interest include misidentification issues, the role of MALDI-TOF MS and molecular tools, rapid diagnostic techniques, genomic approaches, resistance-associated genetic markers, and antifungal stewardship strategies. In addition, clinical management, infection prevention, and outbreak control measures will be key components of this Special Issue.
By bringing together original research articles, reviews, and methodological studies, this Special Issue will serve as a high-impact platform for clinicians, microbiologists, and researchers working toward improved detection, treatment, and control of Candida auris infections.
Prof. Dr. Ibrahim Halil Kilic
Guest Editor
Manuscript Submission Information
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Keywords
- Candida auris
- antifungal resistance
- antifungal susceptibility testing
- molecular diagnostics
- nosocomial fungal infections
- MALDI-TOF MS
- infection control
- multidrug resistance
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