Special Issues

Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bacteriophage Therapy: A Renaissance Weapon—Recent Developments and Application, 3rd Edition submission deadline 31 Mar 2027 | 4 articles | Viewed by 2657 | Submission Open
Keywords: bacteriophages; phage therapy; application of phages; antibiotic-resistance; antibacterial therapies
(This special issue belongs to the Section Bacteriophages)
Plants, Lichens, Fungi, and Algae Extracts and Derivatives with Antimicrobial Properties for Nutrition and Health, Second Edition submission deadline 31 Mar 2027 | 1 articles | Viewed by 1988 | Submission Open
Keywords: antimicrobial and antibiofilm activity; plants/lichens/fungi/algae extracts and derived products with antibacterial, antifungal, antiviral, antiprotozoal and antihelmintic properties; antimicrobial metabolites: quantification and characterization; pharmaceutical formulation; in vivo and in vitro testing; essential oils with antimicrobial properties for the pharmaceutical and food industry; functional foods; plant-based diet; case studies; prevention and treatment of infectious diseases with plant-derived products
(This special issue belongs to the Section Plant-Derived Antibiotics)
Antimicrobial Resistance in Clinical Isolates: Surveillance, Preparedness and Public Health Challenges
edited by Karolina Klesiewicz, Paulina Leśniak and
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1675 | Submission Open
Keywords: carbapenem-resistant Enterobacterales; vancomycin-resistant enterococci; multi-drug-resistant bacteria
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Pharmacokinetics and Pharmacodynamics of Antimicrobials in Pediatric Patients
edited by
submission deadline 31 Mar 2027 | 2 articles | Viewed by 1064 | Submission Open
Keywords: antimicrobials; pediatric patients; neonates; therapeutic drug monitoring (TDM); pharmacokinetic/pharmacodynamic (PK/PD) studies; extracorporeal procedures; PK model-informed studies
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Gram-Positive Cocci: Antimicrobial Resistance, Treatment, Susceptibility, and New Therapeutic Options submission deadline 31 Mar 2027 | 1 articles | Viewed by 1017 | Submission Open
Keywords: Streptococcus spp.; Enterococcus spp.; Staphylococcus spp.; antimicrobial resistance; molecular epidemiology; new therapeutic options
Antibiotic Use in Healthcare-Associated Infections in High Antimicrobial Resistance Settings submission deadline 31 Mar 2027 | 1 articles | Viewed by 906 | Submission Open
Keywords: healthcare-associated infections; antimicrobial resistance; antibiotic stewardship; multidrug-resistant organisms; infection prevention and control
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobials Agents: Latest Advances and Prospects, 2nd Edition
edited by
submission deadline 31 Mar 2027 | 1 articles | Viewed by 530 | Submission Open
Keywords: multidrug-resistant pathogens; infectious diseases; antibiotic resistance; new antimicrobials; drug development; antimicrobial activity; structure–activity relationship (SAR); antimicrobial therapy
(This special issue belongs to the Section Novel Antimicrobial Agents)
Insights into Bacterial Resistance to Beta-Lactam Antibiotics and Treatment Approaches submission deadline 31 Mar 2027 | Viewed by 509 | Submission Open
Keywords: antibiotic resistance; carbapenemase; Klebsiella pneumoniae; high-risk clones
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
The Use of Systemic and Topical Antibiotics in Dentistry: Challenges and Future Perspectives submission deadline 31 Mar 2027 | Viewed by 500 | Submission Open
Keywords: antibiotics; apical abscess; apical periodontitis; endodontic infection; periapical disease; mouth diseases; topical antibiotics; antimicrobial approaches
New Candidates for the Discovery of Antimicrobial Drugs submission deadline 31 Mar 2027 | Viewed by 378 | Submission Open
Keywords: antimicrobial resistance; drug discovery; natural antimicrobial compounds; combination effects; novel antimicrobial agents
(This special issue belongs to the Section Novel Antimicrobial Agents)
Recent Advances in Antimicrobial Photodynamic Therapy submission deadline 31 Mar 2027 | Viewed by 270 | Submission Open
Keywords: photodynamic inactivation; aPDT nanotechnology; light-activated antimicrobial agents; light devices; combination antimicrobial therapy; preclinical and clinical applications; artificial intelligence in aPDT
Antimicrobial Natural Products for One Health Applications submission deadline 31 Mar 2027 | Viewed by 175 | Submission Open
Keywords: antimicrobial resistance (AMR); One Health; natural products; antimicrobial compounds; phytochemicals; essential oils; medicinal plants; marine natural products; microbial metabolites; fungal metabolites; antimicrobial peptides; multidrug-resistant pathogens; biofilms; anti-virulence agents; antibiotic synergy; nanotechnology; metabolomics; drug discovery; veterinary medicine; aquaculture; food safety; environmental microbiology; omics approaches
(This special issue belongs to the Section Plant-Derived Antibiotics)
Staphylococcus aureus Infections: Pathogenesis, Antimicrobial Resistance, and Clinical Management
edited by
submission deadline 31 Mar 2027 | Viewed by 108 | Submission Open
Keywords: Staphylococcus aureus; methicillin-susceptible Staphylococcus aureus (MSSA); methicillin-resistant Staphylococcus aureus (MRSA); hospital-associated MRSA (HA-MRSA); community-associated MRSA (CA-MRSA); livestock-associated MRSA (LA-MRSA); infection; epidemiology; pathogenesis; antimicrobial resistance; virulence factors; clinical management and treatment; infection prevention and control
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Appropriateness and Pharmacology of Antimicrobials
edited by
submission deadline 31 Mar 2027 | Viewed by 99 | Submission Open
Keywords: antimicrobials; pediatrics; pharmacology; appropriateness; clinical pharmacy
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Segmental Bone Defects in the Context of Fracture-Related Infection: Antimicrobial and Reconstructive Perspectives
edited by Janet D. Conway
submission deadline 31 Mar 2027 | 1 articles | Viewed by 78 | Submission Open
Keywords: segmental bone defect; fracture-related infection; antimicrobial therapy; local antibiotic delivery; bone defect reconstruction; induced membrane technique; bone transport; dead space management; biofilm; orthopaedic infection
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice, 2nd Edition
edited by
submission deadline 10 Apr 2027 | Viewed by 91 | Submission Open
Keywords: antibiotic use; antimicrobial stewardship; antimicrobial resistance; diagnostic stewardship; multidrug-resistant organisms
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antibiotic Surveillance and Rational Use in Special Populations: Enhancing Stewardship for Vulnerable Groups submission deadline 15 Apr 2027 | 9 articles | Viewed by 11886 | Submission Open
Keywords: antibiotic stewardship; surveillance systems; special populations; rational use of antibiotics; infectious disease management
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antibiotics and Derived Compounds in the Soil–Plant System: Sources of Contamination, Analytical Methods, Distribution and Risk Assessment submission deadline 20 Apr 2027 | 1 articles | Viewed by 335 | Submission Open
Keywords: antibiotics; soil; crops; sludge; wastewater; determination; occurrence; translocation; risk assessment
Synthesis and Mechanistic Exploration of Novel Antimicrobial Agents
edited by
submission deadline 20 Apr 2027 | Viewed by 32 | Submission Open
Keywords: antimicrobial natural products; antibiotics; antibiotic potentiators; antimicrobial peptides; adjuvants; antimicrobial agents
(This special issue belongs to the Section Novel Antimicrobial Agents)
Beta-Lactam Resistance: Epidemiology and One Health Dynamics submission deadline 25 Apr 2027 | 1 articles | Viewed by 561 | Submission Open
Keywords: beta-lactam antimicrobial; antimicrobial resistance; one health domains; epidemiology; transmission dynamics
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Rational Antibiotic Use in Orthopedics: From Prophylaxis to Treatment
edited by Pablo Slullitel and Marisa Sánchez
submission deadline 28 Apr 2027 | Viewed by 99 | Submission Open
Keywords: orthopedic infections; antimicrobial stewardship; antibiotic therapy; surgical antimicrobial prophylaxis; prosthetic joint infection; fracture-related infection; osteomyelitis; antimicrobial resistance
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Superbugs Unleashed: Global Challenges and Solutions for Extensively Drug-Resistant and Pan-Drug-Resistant Pathogens submission deadline 30 Apr 2027 | 3 articles | Viewed by 13724 | Submission Open
Keywords: antimicrobial resistance; extensively drug-resistant pathogens; pan-drug-resistant bacteria; multidrug-resistant organisms (MDROs); infectious disease control; antibiotic stewardship; novel antimicrobials; rapid diagnostics; global health threats
Evaluation of Emerging Antimicrobials, 2nd Edition submission deadline 30 Apr 2027 | 4 articles | Viewed by 8914 | Submission Open
Keywords: antibacterials; antibiotics; antifungals; antimicrobial agents; antimicrobial resistance; antivirals; bacterial resistance; infections; multidrug resistance; pathogens
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antimicrobial Treatment and Antibiotic Use in Ophthalmology
edited by
submission deadline 30 Apr 2027 | 5 articles | Viewed by 6313 | Submission Open
Keywords: keratitis; conjunctivitis; antibiotics and combinations; antibiotic stewardship; antibiotic resistance; new therapies
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Advances in Antimicrobial Compounds: Exploring Natural, Synthetic, and Repositioned Drugs
edited by and Alexia Barbarossa
submission deadline 30 Apr 2027 | 4 articles | Viewed by 5248 | Submission Open
Keywords: antimicrobial compounds; natural products; synthetic agents; drug repositioning; antimicrobial resistance; synergistic approaches; mechanisms of action; drug development
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Alternative Approaches to Treating Antimicrobial Resistant Infections, 4th Edition submission deadline 30 Apr 2027 | 3 articles | Viewed by 2546 | Submission Open
Keywords: repurposing; anti-infectives; host-targeted therapies; bacteriophages; predatory bacteria; bacteriocins; antimicrobial peptides; nanoparticles; natural compounds; immunotherapy; probiotics; antibiotics
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Global Inequities and Supply Challenges in Access to Antibiotics submission deadline 30 Apr 2027 | 2 articles | Viewed by 2154 | Submission Open
Keywords: antibiotic access; drug shortages; health equity; antimicrobial resistance; access to medicines; pharmaceutical supply chain; essential medicines; pharmacoepidemiology; guideline adherence
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Modern Strategies in Antibacterial Discovery: Integrating In Silico Predictions with In Vitro Validation
edited by
submission deadline 30 Apr 2027 | 1 articles | Viewed by 1092 | Submission Open
Keywords: artificial intelligence/machine learning in drug discovery; total synthesis & methodology lead optimization; target identification & validation; structure-activity relationship (SAR); enzymatic assays; molecular modeling; drug-resistant pathogens
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Design, Synthesis, and Biological Evaluation of Novel Antimicrobial Agents Targeting Resistance Mechanisms submission deadline 30 Apr 2027 | 1 articles | Viewed by 1046 | Submission Open
Keywords: synthesis; antibiotic resistance; biofilm; quorum sensing; cytotoxicity; bacteria; resistance mechanism
Candida auris and Antifungal Resistance: Epidemiology, Detection, and Therapeutic Challenges
edited by Ibrahim Halil Kilic
submission deadline 30 Apr 2027 | 1 articles | Viewed by 1025 | Submission Open
Keywords: Candida auris; antifungal resistance; antifungal susceptibility testing; molecular diagnostics; nosocomial fungal infections; MALDI-TOF MS; infection control; multidrug resistance
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Novel Antimicrobial Agents for Treatment of Staphylococcus aureus Infections
edited by
submission deadline 30 Apr 2027 | 1 articles | Viewed by 948 | Submission Open
Keywords: Staphylococcus aureus; novel antimicrobials; antibiotics; new mechanism of action
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Diagnostics and Antibiotic Therapy for Orthopedic Infections
edited by Karl-Stefan Delank
submission deadline 30 Apr 2027 | 1 articles | Viewed by 624 | Submission Open
Keywords: bone and joint infection; orthopedic infection; periprosthetic joint infection; fracture-related infection; osteomyelitis; septic arthritis; biofilm; rapid diagnostics; local antibiotic delivery; antimicrobial stewardship
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Honey: Antimicrobial and Anti-Infective Function, 2nd Edition submission deadline 30 Apr 2027 | Viewed by 608 | Submission Open
Keywords: antimicrobial activity; biofilms; infections; clinical applications; honey
(This special issue belongs to the Section Novel Antimicrobial Agents)
Exploring Synthetic Organic Chemistry to Combat Pathogenic Infections submission deadline 30 Apr 2027 | Viewed by 402 | Submission Open
Keywords: synthetic organic chemistry; antimicrobial agents; structure–activity relationship (SAR); drug design; molecular docking; drug discovery
(This special issue belongs to the Section Novel Antimicrobial Agents)
Novel Antimicrobials: Biosynthesis, Mechanisms, and Applications Against AMR
edited by and
submission deadline 30 Apr 2027 | Viewed by 126 | Submission Open
Keywords: antimicrobial resistance (AMR); novel antimicrobials; antibiotic discovery; resistance mechanisms; efflux pumps; antimicrobial peptides; phage therapy; anti-virulence strategies
(This special issue belongs to the Section Novel Antimicrobial Agents)
A One Health Perspective on Antibiotic Use and Resistance
edited by José Eduardo Pereira, Telma de Sousa and
submission deadline 30 Apr 2027 | Viewed by 81 | Submission Open
Keywords: zoonoses and public health; veterinary medicine; infectious diseases; One Health and eco-health; bacterial resistance; resistance gene transfer; AMR
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Global Strategies for Antimicrobial Surveillance: Country, Regional and Global Perspectives, Second Edition
edited by and Gabriel Levy-Hara
submission deadline 30 Apr 2027 | Viewed by 74 | Submission Open
Keywords: antimicrobial; stewardship; resistance; consumption; use
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial Activity of Plants Against Emerging or Drug-Resistant Human Pathogens, 2nd Edition submission deadline 30 Apr 2027 | Viewed by 44 | Submission Open
Keywords: anti-infective agents; antimicrobial activity; human pathogens; medicinal plants; natural products; phytodrugs
(This special issue belongs to the Section Plant-Derived Antibiotics)
Antibiotic Residue Detection and Quality Safety Analysis of Honey Products
edited by Xiaofeng Xue and Rui Chen
submission deadline 30 Apr 2027 | Viewed by 34 | Submission Open
Keywords: antibiotic residues; honey; bee products; food safety; LC-MS/MS; multi-residue analysis; sample preparation; QuEChERS; biosensors; veterinary drug residues; risk assessment; honey authentication; contaminant analysis
(This special issue belongs to the Section Antibiotics in Animal Health)
Optimizing Antibiotic Stewardship in Critical Care Medicine
edited by Rosa Reina
submission deadline 30 Apr 2027 | Viewed by 28 | Submission Open
Keywords: antibiotic stewardship; antimicrobial resistance; multidrug-resistant organisms; antimicrobial optimization; PK/PD; rapid diagnostics; therapeutic drug monitoring; critical care
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Emerging Antifungal Resistance and Innovative Strategies in Medical Mycology: From Pathogen Genomics to Translational Therapeutics
edited by Arsa Thammahong
submission deadline 1 May 2027 | 1 articles | Viewed by 586 | Submission Open
Keywords: antifungal resistance; medical mycology; fungal genomics; invasive fungal infections; novel antifungal
(This special issue belongs to the Section Fungi and Their Metabolites)
Antimicrobial Strategies for Sepsis in the Emergency Department: From Empiric Therapy to Targeted Care
edited by
submission deadline 20 May 2027 | Viewed by 257 | Submission Open
Keywords: sepsis; emergency service; hospital; antimicrobial stewardship; drug resistance; microbial; biomarkers; point-of-care testing; anti-bacterial agents; decision support systems; clinical; early diagnosis
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Environmental Fate of Antibiotics Monitoring, Toxicity, Resistance, and Removal Methods, 2nd Edition
edited by
submission deadline 20 May 2027 | Viewed by 34 | Submission Open
Keywords: antimicrobials; high-throughput analysis; antimicrobial resistant bacteria; antimicrobial resistance genes (ARGs); wastewater treatment plant (WWTP); hospital wastewater; livestock environment; water purification plant (WTP); aquatic environment; environmental health risk assessment; antimicrobial resistance (AMR); advanced water treatment
Innovative and Translational Antibiosis Approaches to Tackling Protozoan Parasites: Synergy, Drug Repurposing, Natural Products, Molecular Targets, and Therapeutic Design
edited by
submission deadline 30 May 2027 | 1 articles | Viewed by 2096 | Submission Open
Keywords: drug repurposing for neglected tropical diseases; natural products with antiparasitic activity; synergistic drug combinations; molecular targets and mechanisms of action
Antimicrobial Resistance from a One Health Perspective submission deadline 31 May 2027 | 4 articles | Viewed by 16341 | Submission Open
Keywords: antimicrobial resistance mechanisms; bacterial virulence; clonal diversity; molecular epidemiology; antibiotic use; infectious diseases; One Health
Antibiotic Resistance and Antimicrobial Stewardship in Veterinary Medicine
edited by Tiana Florea, and
submission deadline 31 May 2027 | 6 articles | Viewed by 7474 | Submission Open
Keywords: antimicrobial stewardship; antibiotics; animals; sustainability; drugs; antimicrobial resistance
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Genomic Insights into Dissemination of Multi-Drug Resistance Pathogens submission deadline 31 May 2027 | 3 articles | Viewed by 6609 | Submission Open
Keywords: antimicrobial resistance; genomic surveillance; MDR; gene transfer; One Health
After Antibiotics: Dysbiosis and Drug Resistance in Gut Microbiota
edited by
submission deadline 31 May 2027 | 2 articles | Viewed by 3504 | Submission Open
Keywords: gut microbiota; dysbiosis; antibiotic resistance; resistant genes; probiotics and prebiotics; host–microbe interactions; multidrug-resistant bacteria; post-antibiotic recovery; microbial ecology
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Genetic Blueprints of Resistance, Persistence and Tolerance: Biochemical and Omic Perspectives on Antibiotic Activity
edited by
submission deadline 31 May 2027 | 1 articles | Viewed by 1800 | Submission Open
Keywords: AMR; persistence; tolerance genetic plasticity; genomics; transcriptomics proteomics; biochemical mechanisms; biomarkers
(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)
Epidemiology and Mechanism of Bacterial Resistance to Antibiotics, 2nd Edition submission deadline 31 May 2027 | 1 articles | Viewed by 1416 | Submission Open
Keywords: multi-drug resistant (MDR); classic and molecular epidemiology; plasmids; resistance gene
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
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