Background: Fetal and postnatal development appears to be influenced in multiple ways by exposure to endocrine-disrupting chemicals (EDCs). We used hair biomonitoring to assess the burden of selected EDCs—bisphenol S (BPS), parabens (PBs), tric...
Phthalates are a class of compounds commonly used as plasticizers in various industrial and consumer products. In line with the increasing environmental and biological exposure concerns regarding these compounds, this study investigated the dose-depe...
Aluminum chloride (AlCl3), a widely used inorganic polymeric coagulant in everyday products and industrial materials, has been associated with male reproductive toxicity, though its molecular mechanisms remain poorly understood. To investigate the co...
Amidst rapid urbanization, fine particulate matter (PM2.5) has emerged as a critical environmental challenge in China, posing substantial health risks due to its complex composition and diverse sources. This study provides a seasonally resolved analy...
Environmental hazard-induced male infertility has become a major public health issue. The concealment and accumulation of environmental hazards, and their interactions with the endogenous immune network, have long been underappreciated. As the centra...
Microplastics (MPs) are pervasive contaminants that enter the food chain and cause health issues. However, the size-dependent effects of MPs on lipid metabolism remain inadequately characterized. Using Caenorhabditis elegans (C. elegans), we investig...
Unsymmetrical dimethylhydrazine (UDMH) serves as a high-performance liquid rocket propellant extensively utilized in the global aerospace industry, and its environmental release and leakage (particularly into soil systems) pose severe risks to ecolog...
Clean heating policies were implemented in rural areas of Shaanxi Province in 2017 to alleviate severe air pollution. To evaluate their impacts on bioavailability of PM2.5-bound metals, the influence of emission sources and aerosol acidity on PM2.5-b...
Despite global restrictions like the Minamata Convention, heavy metal contamination in cosmetics remains a critical public health concern, with limited cross-country comparative data on heavy metal concentrations in cosmetics across Asian markets. We...
Drinking water represents a major pathway for human exposure to heavy metals, which are associated with long-term and cumulative health risks. This study investigated eight heavy metals (Ba, V, Cr(VI), Mn, Mo, Ni, Cu, Fe) in three centralized drinkin...
Consumer exposure to chemicals in the EU is currently assessed separately for different products without aggregating exposure from different sources. A more integrated ap proach represents a promising opportunity to improve comprehensive risk evaluat...
The objective of this study was to conduct preliminary tests to determine if differing concentrations of atrazine affected locomotion and/or food-seeking behaviors of juvenile (second and third instar) virile crayfish after a 4-day (96 h) exposure pe...
Prenatal exposure to essential and toxic metals may influence fetal development and birth outcomes. Meconium represents a valuable biomarker of cumulative intrauterine exposure; however, data linking maternal lifestyle and diet to meconium metal conc...
Ubiquitin-specific protease 1 (USP1) is an emerging target for poly(ADP-ribose) polymerase 1 (PARP1) inhibitor-resistant and BRCA1/BRCA2 mutant tumors. USP1 is a deubiquitylating enzyme responsible for the removal of the mono-ubiquitin mark on FANCD2...
Differentiation of villous cytotrophoblasts into syncytiotrophoblasts is essential for placental endocrine function and estradiol production. Caffeine consumption has been linked to altered estradiol levels, but its effects on human trophoblast diffe...
Hexavalent chromium (Cr(VI)) is a recognized environmental and occupational hazard with significant implications for immune function. However, the cell-intrinsic mechanisms by which Cr(VI) coordinately reshapes macrophage polarization together with i...
The ability of the atmosphere to convert primary pollutants into secondary pollutants through atmospheric oxidants is referred to as the atmospheric oxidizing capacity (AOC). This study systematically reviews the generation mechanisms, influencing fa...
Background: Microplastics and nanoplastics, as pervasive and persistent environmental pollutants, are raising growing concerns regarding their potential risks to reproductive health, particularly pregnancy outcomes. Although the reproductive toxicity...
The pervasive toxicity of active aluminum (Al3+) in acidic red soils threatens agroecosystem sustainability, with conventional chemical stabilizers facing cost and secondary pollution constraints. This study evaluated rice husk/sawdust and their pyro...
Based on continuous field observations conducted at the Shangdianzi Regional Atmospheric Background Station from 21 October to 20 November 2024 and from 1 December 2024, to 2 January 2025, this study systematically analyzed the concentration levels,...
Determining the concentration of fatty acid ethyl esters (FAEEs), ethyl sulfate (EtS), and ethyl glucuronide (EtG) is crucial for establishing the true scale of prenatal alcohol exposure (PAE) and enabling early diagnosis of fetal alcohol spectrum di...
Heavy metal pollution of farmland has emerged as a pressing global environmental challenge, which threatens food security, ecological integrity, and human health [...]
In industrial settings, one of the key environmental challenges is the remediation of soil contaminated by hydrocarbons. Washing the soil with surfactants mobilises and extracts these compounds, making them easier to treat. As it enables the recovery...
The ubiquity and environmental persistence of per- and polyfluoroalkyl substances (PFASs) have raised significant concerns about their detrimental effects on human health. Collective scientific efforts are increasingly focused on elucidating PFAS tox...
Antibiotic resistance gene (ARG) monitoring in environmental systems increasingly relies on DNA-based molecular approaches; however, the extent to which DNA extraction strategies bias downstream resistome interpretation remains insufficiently underst...
(1) Background: Hot pot bases are susceptible to phthalate (PAE) contamination due to their high lipid content. Standard risk models often fail to capture extreme values, leading to biased exposure estimates. This study characterized dibutyl phthalat...
Phosphogypsum (PG) is a byproduct of wet-process phosphoric acid production and contains soluble phosphorus (P), fluorine (F), and other harmful impurities in addition to calcium sulfate. Its acidic leachate enriched with P and F poses long-term risk...
This study assesses the presence and distribution of per- and polyfluoroalkyl substances (PFAS) and polybrominated diphenyl ethers (PBDEs) in the surface waters of the Itupararanga Reservoir and the Sorocaba River, Brazil. Samples collected during th...
Agricultural watersheds are undergoing rapid rural–urban transitions, yet the relative contributions of diffuse agricultural runoff versus rural domestic and point sources to organophosphate esters (OPEs) pollution remain poorly understood. Thi...
While the adverse health effects of bisphenol A (BPA) or high-fat diet (HFD) exposure alone have been relatively well documented, the mechanisms underlying their combined impact on insulin resistance and type 2 diabetes remain poorly understood. In t...
The increased mobilization of Rare Earth Elements (REEs), due to emerging technologies, could impact human health. The study assessed the effects of CeO2 nanopowder (100 μg/mL) in human intestinal cells (HT-29) following both acute (24 h) and, a n...
Isothiazolinones are commonly used biocides that are extensively used in industrial areas and household products. The extensive usage of isothiazolinones raises concerns regarding their adverse human health effects. Isothiazolinones are readily absor...
This study presents the first systematic investigation of Volatile Organic Compounds (VOC) source profiles from key industrial sectors in Chongqing, China. Source-specific emission data were collected from fifteen representative facilities encompassi...
Background: Exposure to environmental pollutants, especially endocrine-disrupting chemicals, disproportionately affects vulnerable populations like pregnant women, lactating mothers, and preterm infants. This study aimed to assess the detection patte...
Background: Evidence linking chlorinated polyfluoroalkyl ether sulfonic acids (Cl-PFESAs) to preterm birth (PTB) is limited, and their relationships with the metabolome remain unexplored. Aims: Our study aimed to explore the role of the metabolome in...
Silicosis, an irreversible occupational lung disease resulting from prolonged exposure to respirable crystalline silica, faces challenges due to limitations in existing mammalian models. This study evaluated whether laboratory-prepared respirable &al...
This scoping review examined published evidence linking environmental and industrial exposures to breast cancer, synthesizing studies conducted between 2015 and 2025. Using the Arksey and O’Malley framework, 51 peer-reviewed studies were identi...
Cement production exerts a significant negative impact on the environment through the emission of greenhouse gases, particulate matter (PM), heavy metals, and other toxic substances into the atmosphere, soil, and bodies of water, degrading the enviro...
Procambarus clarkii (red swamp crayfish) exhibits physiological plasticity that enables adaptation to variable freshwater conditions, such as those in Lake Trasimeno. This study examined whether fluctuations in hydrometric level and associated physic...
As a typical halogenated hydrocarbon environmental pollutant, 1,2-dichloroethane (1,2-DCE) exhibits clinically confirmed hepatotoxicity with incompletely understood mechanisms. This study integrated network toxicology, molecular docking, and in vitro...
This study systematically investigates cadmium (Cd) accumulation and translocation mechanisms in woody plants through integrated analysis of 16 species. Roots consistently exhibited the highest Cd concentrations (0.26 ± 0.13 mg/kg), serving as...
Although particulate matter has been associated with sleep problems, the effects of PM2.5-bound organophosphate esters (OPEs) on children’s sleep remain unclear. OPEs have neurotoxic and endocrine-disrupting effects that may disrupt sleep&ndash...
To investigate the distribution, sources, and partitioning of heavy metals at the sediment–water interface in the northern Jiangsu coastal waters, seawater and sediment samples were collected from 24 stations east of Yanwei Port in April 2021....
The increasing environmental release of nano-titanium dioxide (nTiO2) due to its widespread industrial application raises concerns about its potential effects on aquatic ecosystems, particularly marine organisms. Fertilization, a critical reproductiv...
Synthetic cathinones, frequently used in chemsex, are difficult to identify in postmortem blood due to their short half-life and in vitro degradation. This unusual case of chemsex involving 3-CMC highlights the importance of freezing a blood aliquot...
(1) Background: Energy-based transurethral resection of bladder tumor (TURBT) generates surgical smoke that may contain hazardous volatile organic compounds (VOCs), yet surgeon breathing-zone exposure during transurethral surgery remains insufficient...
The intensive cultivation of greenhouse tomatoes generates massive quantities of vegetative residues often laden with potentially complex pesticide contaminants, posing a dual challenge of waste management and environmental toxicity. This study inves...
Excessive fluoride exposure induces developmental neurotoxicity, but effective preventive strategies are currently scarce. Melatonin (Mel), a lipophilic hormone secreted by the pineal gland, exerts antioxidant, anti-inflammatory, and neuroprotective...
Soil ecosystems are seriously contaminated by microplastics of varying particle sizes, yet the ecological consequences across a broader size spectrum remain poorly understood. We conducted a 360-day field experiment to examine the effects of seven mi...
Non-point source pollution poses a severe threat to the water quality of the Li River. This study conducted field monitoring of pollution loads from different land-use types on Maozhou Island in the Li River during the 2023 rainy season. Runoff water...
Get Alerted
Add your email address to receive forthcoming issues of this journal.
