Skip to Content

Stats, Volume 6, Issue 1

2023 March - 29 articles

Cover Story: To accelerate the results of a clinical trial, investigators often rely on intermediate or “surrogate” endpoints that can be obtained earlier than the ultimate or “true” endpoint of interest.  For example, tumor growth may be observed well in advance of death in a cancer setting. There are settings in which the proposed surrogate endpoint is positively correlated with the true endpoint, but the treatment has opposite effects on the surrogate and true endpoints, a phenomenon labeled as “surrogate paradox”. Covariate information may be useful in predicting an individual’s risk of surrogate paradox. In this work, we extend methods to estimate the risk of this paradox as a function of different baseline covariates (for example, males versus females). View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (29)

  • Article
  • Open Access
1 Citations
2,473 Views
14 Pages

Efficient Two-Stage Analysis for Complex Trait Association with Arbitrary Depth Sequencing Data

  • Zheng Xu,
  • Song Yan,
  • Shuai Yuan,
  • Cong Wu,
  • Sixia Chen,
  • Zifang Guo and
  • Yun Li

19 March 2023

Sequencing-based genetic association analysis is typically performed by first generating genotype calls from sequence data and then performing association tests on the called genotypes. Standard approaches require accurate genotype calling (GC), whic...

  • Article
  • Open Access
2,770 Views
18 Pages

18 March 2023

A phylogenetic regression model that incorporates the network structure allowing the reticulation event to study trait evolution is proposed. The parameter estimation is achieved through the maximum likelihood approach, where an algorithm is develope...

  • Article
  • Open Access
2,368 Views
12 Pages

Consecutive-k1 and k2-out-of-n: F Structures with a Single Change Point

  • Ioannis S. Triantafyllou and
  • Miltiadis Chalikias

16 March 2023

In the present paper, we establish a new consecutive-type reliability model with a single change point. The proposed structure has two common failure criteria and consists of two different types of components. The general framework for constructing t...

  • Brief Report
  • Open Access
2,685 Views
7 Pages

15 March 2023

Using geometric considerations, we provided a clear derivation of the integral representation for the error function, known as the Craig formula. We calculated the corresponding power series expansion and proved the convergence. The same geometric me...

  • Article
  • Open Access
13 Citations
4,393 Views
20 Pages

3 March 2023

The COVID-19 outbreak has rapidly affected global economies and the parties involved. There was a need to ensure the sustainability of corporate finance and avoid bankruptcy. The reactions of individuals were not routine, but covered a wide range of...

  • Article
  • Open Access
2,158 Views
16 Pages

22 February 2023

The purpose of this note is to provide a description of the weak convergence of the random resample size bootstrap empirical process. The principal results are used to estimate the sample rank correlation coefficients using Spearman’s and Kenda...

  • Brief Report
  • Open Access
7 Citations
3,739 Views
11 Pages

19 February 2023

Researchers interested in the assessment of substance use trajectories, and predictors of change, have several data analysis options. These include, among others, generalized estimating equations and latent growth curve modeling. One difficulty in th...

  • Communication
  • Open Access
4 Citations
3,500 Views
9 Pages

17 February 2023

This work presents a brief review on the modern approaches to data modeling by the methods developed in the quantum physics during the last one hundred years. Quantum computers and computations have already been widely investigated theoretically and...

  • Article
  • Open Access
6 Citations
2,620 Views
23 Pages

Incorporating Covariates into Measures of Surrogate Paradox Risk

  • Fatema Shafie Khorassani,
  • Jeremy M. G. Taylor,
  • Niko Kaciroti and
  • Michael R. Elliott

17 February 2023

Clinical trials often collect intermediate or surrogate endpoints other than their true endpoint of interest. It is important that the treatment effect on the surrogate endpoint accurately predicts the treatment effect on the true endpoint. There are...

  • Article
  • Open Access
2 Citations
3,733 Views
10 Pages

13 February 2023

To what extent do high school students’ course grades align with their scores on standardized college admission tests? People sometimes make the argument that grades are “inflated”, but many school districts only use outcome-based d...

  • Article
  • Open Access
2 Citations
2,128 Views
19 Pages

9 February 2023

In this paper, we develop a novel soft-clipping discrete beta GARCH (ScDBGARCH) model that provides an available method to model bounded time series with under-dispersion, equi-dispersion or over-dispersion. The new model not only allows positive dep...

  • Article
  • Open Access
4 Citations
1,906 Views
14 Pages

8 February 2023

In this article, we establish a new class of nonparametric Shewhart-type control charts based on order statistics with signaling runs-type rules. The proposed charts offer to the practitioner the opportunity to reach, as close as possible, a pre-spec...

  • Article
  • Open Access
3 Citations
3,150 Views
11 Pages

6 February 2023

This paper proposes a heuristic reward reinforcement learning framework for point cloud registration. As an essential step of many 3D computer vision tasks such as object recognition and 3D reconstruction, point cloud registration has been well studi...

  • Article
  • Open Access
6 Citations
2,751 Views
15 Pages

Farlie–Gumbel–Morgenstern Bivariate Moment Exponential Distribution and Its Inferences Based on Concomitants of Order Statistics

  • Sasikumar Padmini Arun,
  • Christophe Chesneau,
  • Radhakumari Maya and
  • Muhammed Rasheed Irshad

3 February 2023

In this research, we design the Farlie–Gumbel–Morgenstern bivariate moment exponential distribution, a bivariate analogue of the moment exponential distribution, using the Farlie–Gumbel–Morgenstern approach. With the analysis...

  • Article
  • Open Access
1 Citations
2,192 Views
21 Pages

30 January 2023

In this article, we introduce two new bivariate Kumaraswamy (KW)-type distributions with univariate Kumaraswamy marginals (under certain parametric restrictions) that are less restrictive in nature compared with several other existing bivariate beta...

  • Article
  • Open Access
1 Citations
2,578 Views
23 Pages

29 January 2023

Many population-based surveys have binary responses from a large number of individuals in each household within small areas. One example is the Nepal Living Standards Survey (NLSS II), in which health status binary data (good versus poor) for each in...

  • Article
  • Open Access
14 Citations
3,129 Views
17 Pages

25 January 2023

In the social sciences, the performance of two groups is frequently compared based on a cognitive test involving binary items. Item response models are often utilized for comparing the two groups. However, the presence of differential item functionin...

  • Article
  • Open Access
3 Citations
3,824 Views
23 Pages

Informative g-Priors for Mixed Models

  • Yu-Fang Chien,
  • Haiming Zhou,
  • Timothy Hanson and
  • Theodore Lystig

16 January 2023

Zellner’s objective g-prior has been widely used in linear regression models due to its simple interpretation and computational tractability in evaluating marginal likelihoods. However, the g-prior further allows portioning the prior variabilit...

  • Article
  • Open Access
4 Citations
2,639 Views
19 Pages

A Novel Flexible Class of Intervened Poisson Distribution by Lagrangian Approach

  • Muhammed Rasheed Irshad,
  • Mohanan Monisha,
  • Christophe Chesneau,
  • Radhakumari Maya and
  • Damodaran Santhamani Shibu

15 January 2023

The zero-truncated Poisson distribution (ZTPD) generates a statistical model that could be appropriate when observations begin once at least one event occurs. The intervened Poisson distribution (IPD) is a substitute for the ZTPD, in which some inter...

  • Article
  • Open Access
11 Citations
5,170 Views
17 Pages

Statistical Prediction of Future Sports Records Based on Record Values

  • Christina Empacher,
  • Udo Kamps and
  • Grigoriy Volovskiy

11 January 2023

Point prediction of future record values based on sequences of previous lower or upper records is considered by means of the method of maximum product of spacings, where the underlying distribution is assumed to be a power function distribution and a...

  • Article
  • Open Access
7 Citations
3,222 Views
18 Pages

4 January 2023

This work presents the statistical analysis of a monthly average temperatures time series in several European cities using a state space approach, which considers models with a deterministic seasonal component and a stochastic trend. Temperature rise...

  • Article
  • Open Access
2 Citations
2,328 Views
14 Pages

1 January 2023

We present REGA, a new adaptive-sampling-based algorithm for the control of finite-horizon Markov decision processes (MDPs) with very large state spaces and small action spaces. We apply a variant of the ϵ-greedy multiarmed bandit algorithm to...

  • Article
  • Open Access
3,406 Views
32 Pages

Applying the Multilevel Approach in Estimation of Income Population Differences

  • Venera Timiryanova,
  • Dina Krasnoselskaya and
  • Natalia Kuzminykh

29 December 2022

Income inequality remains one of the most burning issues discussed in the world. The difficulty of the problem arises from its multiple manifestations at regional and local levels and unique patterns within countries. This paper employs a multilevel...

  • Article
  • Open Access
1 Citations
3,140 Views
17 Pages

Do Deep Reinforcement Learning Agents Model Intentions?

  • Tambet Matiisen,
  • Aqeel Labash,
  • Daniel Majoral,
  • Jaan Aru and
  • Raul Vicente

28 December 2022

Inferring other agents’ mental states, such as their knowledge, beliefs and intentions, is thought to be essential for effective interactions with other agents. Recently, multi-agent systems trained via deep reinforcement learning have been sho...

  • Article
  • Open Access
2,671 Views
20 Pages

Estimating Smoothness and Optimal Bandwidth for Probability Density Functions

  • Dimitris N. Politis,
  • Peter F. Tarassenko and
  • Vyacheslav A. Vasiliev

27 December 2022

The properties of non-parametric kernel estimators for probability density function from two special classes are investigated. Each class is parametrized with distribution smoothness parameter. One of the classes was introduced by Rosenblatt, another...

  • Communication
  • Open Access
1 Citations
2,379 Views
13 Pages

24 December 2022

We apply the data cloning method to estimate a medium-scale dynamic stochastic general equilibrium model. The data cloning algorithm is a numerical method that employs replicas of the original sample to approximate the maximum likelihood estimator as...

  • Article
  • Open Access
1,852 Views
16 Pages

A Semiparametric Tilt Optimality Model

  • Chathurangi H. Pathiravasan and
  • Bhaskar Bhattacharya

22 December 2022

Practitioners often face the situation of comparing any set of k distributions, which may follow neither normality nor equality of variances. We propose a semiparametric model to compare those distributions using an exponential tilt method. This exte...

XFacebookLinkedIn
Stats - ISSN 2571-905X