- Article
Mice Treated Subcutaneously with Mouse LPS-Converted PrPres or LPS Alone Showed Brain Gene Expression Profiles Characteristic of Prion Disease
- Dagnachew Hailemariam,
- Seyed Ali Goldansaz,
- Nathalie Daude,
- David S. Wishart and
- Burim N. Ametaj
Previously, we showed that bacterial lipopolysaccharide (LPS) converts mouse PrPC protein to a beta-rich isoform (moPrPres) resistant to proteinase K. In this study, we aimed to test if the LPS-converted PrPres is infectious and alters the expression...

