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Processes, Volume 6, Issue 2

February 2018 - 10 articles

Cover Story: Cell-to-cell variability exists to some degree in any given cell population. In this work, we propose a method for performing sensitivity analysis of cell population dynamics, called Molecular Density Function Perturbation (MDFP). We apply MDFP to a mathematical model of programmed cell death (apoptosis) signaling pathway in HeLa cell population, to elucidate the molecules governing apoptosis decision making. The picture shows cell-to-cell variability in apoptosis, where cells of different colors illustrate cell populations from different time points. The picture also shows the apoptosis signaling network and the probability density functions of cleaved poly (ADP-ribose) polymerase concentration, a marker of apoptosis. View this paper
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Articles (10)

  • Article
  • Open Access
17 Citations
14,935 Views
15 Pages

13 February 2018

Centrifugal pumps are widely used in the industry, especially in the oil and gas sector for fluids transport. Classically, these are designed to transfer single phase fluids (e.g., water) at high flow rates and relatively low pressures when compared...

  • Article
  • Open Access
17 Citations
24,832 Views
21 Pages

11 February 2018

Equipment throughput is one of the most critical parameters for production planning and scheduling, which is often derived by optimization techniques to achieve business goals. However, in semiconductor manufacturing, up-to-date and reliable equipmen...

  • Feature Paper
  • Article
  • Open Access
14 Citations
6,777 Views
19 Pages

11 February 2018

Grinding circuits typically contribute disproportionately to the overall cost of ore beneficiation and their optimal operation is therefore of critical importance in the cost-effective operation of mineral processing plants. This can be challenging,...

  • Article
  • Open Access
28 Citations
20,593 Views
8 Pages

Process Modification of Pharmaceutical Tablet Manufacturing Operations: An Eco-Efficiency Approach

  • Muna Hindiyeh,
  • Tala Altalafha,
  • Manar Al-Naerat,
  • Hakam Saidan,
  • Ahmed Al-Salaymeh,
  • Lu’ay Sbeinati and
  • Motasem N. Saidan

9 February 2018

A process improvement in a tablet manufacturing process within a pharmaceutical industry was carried out based on an eco-efficiency approach. As it is one of the most energy consuming processes in the production line, the tablet manufacturing process...

  • Feature Paper
  • Article
  • Open Access
9 Citations
7,110 Views
21 Pages

7 February 2018

Emulsion polymerization process provides a unique polymerization locus that has a confined tiny space with a higher polymer concentration, compared with the corresponding bulk polymerization, especially for the ab initio emulsion polymerization. Assu...

  • Feature Paper
  • Article
  • Open Access
6 Citations
5,868 Views
20 Pages

5 February 2018

The separation of small molecule gases by membrane technologies can help performance enhancement and process intensification for emerging advanced fossil energy systems with CO2 capture capacity. This paper reports the demonstration of controlled mod...

  • Article
  • Open Access
21 Citations
6,217 Views
15 Pages

An Automatic Monitoring System for High-Frequency Measuring and Real-Time Management of Cyanobacterial Blooms in Urban Water Bodies

  • Viet Tran Khac,
  • Yi Hong,
  • Denis Plec,
  • Bruno J. Lemaire,
  • Philippe Dubois,
  • Mohamed Saad and
  • Brigitte Vinçon-Leite

30 January 2018

Urban lakes mitigate the negative impacts on the hydrological cycle and improve the quality of life in cities. Worldwide, the concern increases for the protection and management of urban water bodies. Since the physical-chemical and biological condit...

  • Feature Paper
  • Article
  • Open Access
4 Citations
6,590 Views
12 Pages

Multivariable Real-Time Control of Viscosity Curve for a Continuous Production Process of a Non-Newtonian Fluid

  • Roberto Mei,
  • Massimiliano Grosso,
  • Francesc Corominas,
  • Roberto Baratti and
  • Stefania Tronci

30 January 2018

The application of a multivariable predictive controller to the mixing process for the production of a non-Newtonian fluid is discussed in this work. A data-driven model has been developed to describe the dynamic behaviour of the rheological properti...

  • Article
  • Open Access
2 Citations
5,237 Views
6 Pages

Investigation of the Interaction between Benzene and SXFA Using DFT

  • Katherine M. E. Stewart,
  • Ian P. Hamilton and
  • Alexander Penlidis

25 January 2018

Density Functional Theory (DFT) studies were conducted to evaluate the sensing mechanism between benzene and a polymeric sensing material, referred to as SXFA, which contains trifluoro-groups and OH-groups. These studies were undertaken to improve th...

  • Feature Paper
  • Article
  • Open Access
1 Citations
5,546 Views
13 Pages

23 January 2018

Studies performed at single-cell resolution have demonstrated the physiological significance of cell-to-cell variability. Various types of mathematical models and systems analyses of biological networks have further been used to gain a better underst...

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Processes - ISSN 2227-9717