Processes, Volume 6, Issue 2 (February 2018) – 10 articles
Cover Story (view full-size image):
Cell-to-cell variability exists to some degree in any given cell population. In this work, we propose a method for performing sensitivity analysis of cell population dynamics, called Molecular Density Function Perturbation (MDFP). We apply MDFP to a mathematical model of programmed cell death (apoptosis) signaling pathway in HeLa cell population, to elucidate the molecules governing apoptosis decision making. The picture shows cell-to-cell variability in apoptosis, where cells of different colors illustrate cell populations from different time points. The picture also shows the apoptosis signaling network and the probability density functions of cleaved poly (ADP-ribose) polymerase concentration, a marker of apoptosis. View this paper
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader
to open them.
Previous Issue
Next Issue