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Biomolecules, Volume 13, Issue 6
June 2023 - 142 articles
Cover Story: Extracellular vesicles (EVs) are membrane-enclosed nano-sized particles, identified as novel mediators of cell–cell communication. The present review delineates how EVs from different hematological tumors influence the cells in the tumor microenvironment, such as immune cells, stromal cells, fibroblasts and endothelial cells, as well as various extracellular matrix components, ultimately aiding in the growth and metastatic dissemination of the tumor. The advancement of EV research in the past few decades not only identifies EVs as an important contributor in drug resistance, but also highlights their impeccable use as biomarkers and therapeutics. Despite the current challenges, EVs research has shown promises in the treatment of different forms of hematological malignancies in diverse ways. View this paper
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Biomolecules - ISSN 2218-273X