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Antibiotics, Volume 11, Issue 6

June 2022 - 126 articles

Cover Story: Our observational retrospective study aimed to analyze whether/how the spectrum of bacterial pathogens and their resistance to antibiotics changed during the worst part of the COVID-19 pandemic among intensive care patients in University Hospital Olomouc, Czech Republic. The study demonstrated an increase in the frequency of ESBL-positive strains of some species (Serratia marcescens and Enterobacter cloacae); on the other hand, the resistance decreased (Escherichia coliAcinetobacter baumannii) or the proportion of resistant strains remained unchanged in comparison to the pre-covid period (Klebsiella pneumoniaeEnterococcus faecium). Changes in resistance were caused mainly due to the confirmed clonal spread of identical bacterial isolates among patients. The importance of infection control is discussed, not only for dealing with SARS-CoV-2 but also for limiting the spread of bacteria. View this paper
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Articles (126)

  • Article
  • Open Access
25 Citations
4,412 Views
14 Pages

Companion Animals as Potential Reservoirs of Antibiotic Resistant Diarrheagenic Escherichia coli in Shandong, China

  • Lulu Cui,
  • Xiaonan Zhao,
  • Ruibo Li,
  • Yu Han,
  • Guijuan Hao,
  • Guisheng Wang and
  • Shuhong Sun

Antibiotic resistance genes of Escherichia coli (E. coli) from companion animals were still poorly understood. Here, we investigated the extended-spectrum β-lactamases (ESBLs) resistance genes of E. coli from companion animals in Shandong, China...

  • Article
  • Open Access
31 Citations
5,295 Views
13 Pages

Antifungal, Antioxidant and Antibiofilm Activities of Essential Oils of Cymbopogon spp.

  • Wafa Rhimi,
  • Mona A. Mohammed,
  • Aya Attia Koraney Zarea,
  • Grazia Greco,
  • Maria Tempesta,
  • Domenico Otranto and
  • Claudia Cafarchia

Essential oils (EOs) of Cymbopogon citratus and Cymbopogon proximus are known as sources of monoterpenes and sesquiterpenoids, although their biological activities have not been well investigated. In this study, the compositions of C. citratus and C....

  • Article
  • Open Access
3,360 Views
12 Pages

Background:Staphylococcus aureus bloodstream infection (SA-BSI) causes morbidity and mortality. We established a management protocol for patients with SA-BSI aimed at improving quality of care and patient outcomes. Methods: A retrospective pre–...

  • Article
  • Open Access
43 Citations
5,645 Views
13 Pages

Long-Term Impact of the COVID-19 Pandemic on In-Hospital Antibiotic Consumption and Antibiotic Resistance: A Time Series Analysis (2015–2021)

  • Marianna Meschiari,
  • Lorenzo Onorato,
  • Erica Bacca,
  • Gabriella Orlando,
  • Marianna Menozzi,
  • Erica Franceschini,
  • Andrea Bedini,
  • Adriana Cervo,
  • Antonella Santoro and
  • Mario Sarti
  • + 7 authors

The coronavirus disease 2019 (COVID-19)-pandemic-related overload of health systems has compromised the application of antimicrobial stewardship (AS) models and infection prevention and control (IPC) programs. We aimed to evaluate the impact of COVID...

  • Article
  • Open Access
2 Citations
4,049 Views
14 Pages

Clinical Trial for Evaluating the Effectiveness and Safety of a New Dental Plaque Removal Device: Microscale Mist Unit

  • Hiroki Hihara,
  • Kuniyuki Izumita,
  • Misato Iwatsu,
  • Tomoya Sato,
  • Ryo Tagaino,
  • Kenta Shobara,
  • Yuta Shinohara,
  • Takanori Hatakeyama,
  • Chie Kayaba and
  • Mariko Sato
  • + 6 authors

This study evaluates the effectiveness and safety of a microscale mist unit (MSM-UNIT) that sprays high-speed fine water droplets to remove dental plaque adhering to the oral mucosa (tongue and palate) and tooth surface. Fifteen patients who had diff...

  • Article
  • Open Access
12 Citations
3,419 Views
10 Pages

Heparin-Binding Protein (HBP), Neutrophil Gelatinase-Associated Lipocalin (NGAL) and S100 Calcium-Binding Protein B (S100B) Can Confirm Bacterial Meningitis and Inform Adequate Antibiotic Treatment

  • Maria Obreja,
  • Egidia Gabriela Miftode,
  • Iulian Stoleriu,
  • Daniela Constantinescu,
  • Andrei Vâță,
  • Daniela Leca,
  • Corina Maria Cianga,
  • Olivia Simona Dorneanu,
  • Mariana Pavel-Tanasa and
  • Petru Cianga

The empirical administration of antibiotics for suspected bacterial meningitis denotes a poor bacterial stewardship. In this context, the use of biomarkers can distinguish between bacterial and viral infections before deciding treatment. Our study as...

  • Article
  • Open Access
18 Citations
3,358 Views
10 Pages

Patterns and Determinants of Antibiotic Use Behaviors among Rural Community Residents in Eastern China

  • Yanhuan Wang,
  • Xinping Zhao,
  • Yurong Li,
  • Na Wang,
  • Feng Jiang,
  • Helen Lambert,
  • Fei Yan,
  • Chaowei Fu and
  • Qingwu Jiang

Inappropriate antibiotic use may lead to antibiotic resistance, which has become a serious global crisis. Addressing suboptimal antibiotic use in the general population can play a significant role in the fight against antimicrobial resistance. This s...

  • Article
  • Open Access
7 Citations
2,945 Views
11 Pages

Effect of Fluoroquinolone Use in Primary Care on the Development and Gradual Decay of Escherichia coli Resistance to Fluoroquinolones: A Matched Case-Control Study

  • Peter Konstantin Kurotschka,
  • Chiara Fulgenzio,
  • Roberto Da Cas,
  • Giuseppe Traversa,
  • Gianluigi Ferrante,
  • Orietta Massidda,
  • Ildikó Gágyor,
  • Richard Aschbacher,
  • Verena Moser and
  • Elisabetta Pagani
  • + 2 authors

The reversibility of bacterial resistance to antibiotics is poorly understood. Therefore, the aim of this study was to determine, over a period of five years, the effect of fluoroquinolone (FQ) use in primary care on the development and gradual decay...

  • Review
  • Open Access
63 Citations
10,087 Views
22 Pages

Antimicrobial Resistance Development Pathways in Surface Waters and Public Health Implications

  • Joseph Kusi,
  • Catherine Oluwalopeye Ojewole,
  • Akinloye Emmanuel Ojewole and
  • Isaac Nwi-Mozu

Human health is threatened by antibiotic-resistant bacteria and their related infections, which cause thousands of human deaths every year worldwide. Surface waters are vulnerable to human activities and natural processes that facilitate the emergenc...

  • Article
  • Open Access
19 Citations
15,919 Views
20 Pages

A Qualitative Study on the Design and Implementation of the National Action Plan on Antimicrobial Resistance in the Philippines

  • Maria Margarita M. Lota,
  • Alvin Qijia Chua,
  • Karen Azupardo,
  • Carlo Lumangaya,
  • Katherine Ann V. Reyes,
  • Sharon Yvette Angelina M. Villanueva,
  • Helena Legido-Quigley and
  • Evalyn A. Roxas

Antimicrobial resistance (AMR) is a global public health threat that warrants urgent attention. Countries developed their national action plans (NAPs) following the launch of the Global Action Plan on AMR in 2015. The development and implementation o...

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Antibiotics - ISSN 2079-6382