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Biosensors, Volume 13, Issue 12

December 2023 - 47 articles

Cover Story: Periodontal disease, characterized by persistent inflammation impacting the gingival tissues supporting the teeth, can result in tooth loss attributed to the continual accumulation of dental plaque. Here, a biosensing platform employing the molecularly imprinted polymer (MIP) technique was devised through protein imprinting with the specific biomarker IL-1β, recognized as a pivotal indicator in diagnosing periodontitis. This MIP-based biosensor was integrated with a smartphone interface, thereby constituting a mobile point-of-care testing (POCT) platform designed for expeditious diagnostic purposes. The proposed scheme, featuring artificial antibody-based biosensors, exhibited a robust electrochemical performance that aligns with established periodontitis detection guidelines. View this paper
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Articles (47)

  • Communication
  • Open Access
3 Citations
2,537 Views
9 Pages

18 December 2023

Refractive index sensing based on surface plasmon resonance (SPR) is a highly efficient label-free technique for biomolecular detection. The performance of this method is defined by the dielectric properties of a sensing layer and its structure. Nano...

  • Article
  • Open Access
26 Citations
3,598 Views
15 Pages

18 December 2023

Butylated hydroxyanisole (BHA) is a synthetic phenolic antioxidant widely used in various food matrices to prevent oxidative rancidity. However, its presence has been associated with liver damage and carcinogenesis in animals. Thus, an electrochemica...

  • Article
  • Open Access
4 Citations
3,616 Views
13 Pages

Phenotypic Characterization of 2D and 3D Prostate Cancer Cell Systems Using Electrical Impedance Spectroscopy

  • Lexi L. Crowell,
  • Juan Sebastian Yakisich,
  • Brian Aufderheide and
  • Tayloria N. G. Adams

18 December 2023

Prostate cancer is the second leading cause of death in men. A challenge in treating prostate cancer is overcoming cell plasticity, which links cell phenotype changes and chemoresistance. In this work, a microfluidic device coupled with electrical im...

  • Article
  • Open Access
3 Citations
3,644 Views
13 Pages

Rapid On-Site Detection of Arboviruses by a Direct RT-qPCR Assay

  • Moufid Mhamadi,
  • Giulia Mencattelli,
  • Alioune Gaye,
  • El Hadji Ndiaye,
  • Aïssatou Aïcha Sow,
  • Martin Faye,
  • Marie Henriette Dior Ndione,
  • Moussa Moïse Diagne,
  • Moundhir Mhamadi and
  • Ousmane Faye
  • + 4 authors

16 December 2023

Arthropod-borne diseases currently constitute a source of major health concerns worldwide. They account for about 50% of global infectious diseases and cause nearly 700,000 deaths every year. Their rapid increase and spread constitute a huge challeng...

  • Article
  • Open Access
5 Citations
4,123 Views
18 Pages

DNA Probes for Cas12a-Based Assay with Fluorescence Anisotropy Enhanced Due to Anchors and Salts

  • Irina V. Safenkova,
  • Alexey V. Samokhvalov,
  • Kseniya V. Serebrennikova,
  • Sergei A. Eremin,
  • Anatoly V. Zherdev and
  • Boris B. Dzantiev

16 December 2023

CRISPR/Cas12a is a potent biosensing tool known for its high specificity in DNA analysis. Cas12a recognizes the target DNA and acquires nuclease activity toward single-stranded DNA (ssDNA) probes. We present a straightforward and versatile approach t...

  • Article
  • Open Access
3,038 Views
14 Pages

Enhancing the Study of Quantal Exocytotic Events: Combining Diamond Multi-Electrode Arrays with Amperometric PEak Analysis (APE) an Automated Analysis Code

  • Giulia Tomagra,
  • Alice Re,
  • Veronica Varzi,
  • Pietro Aprà,
  • Adam Britel,
  • Claudio Franchino,
  • Sofia Sturari,
  • Nour-Hanne Amine,
  • Remco H. S. Westerink and
  • Valentina Carabelli
  • + 1 author

16 December 2023

MicroGraphited-Diamond-Multi Electrode Arrays (μG-D-MEAs) can be successfully used to reveal, in real time, quantal exocytotic events occurring from many individual neurosecretory cells and/or from many neurons within a network. As μG-D-MEAs ar...

  • Article
  • Open Access
4 Citations
2,761 Views
14 Pages

Optimized Copper-Based Microfeathers for Glucose Detection

  • Carlota Guati,
  • Lucía Gómez-Coma,
  • Marcos Fallanza and
  • Inmaculada Ortiz

15 December 2023

Diabetes is expected to rise substantially by 2045, prompting extensive research into accessible glucose electrochemical sensors, especially those based on non-enzymatic materials. In this context, advancing the knowledge of stable metal-based compou...

  • Review
  • Open Access
10 Citations
3,708 Views
23 Pages

Low-Cost Plant-Based Metal and Metal Oxide Nanoparticle Synthesis and Their Use in Optical and Electrochemical (Bio)Sensors

  • Iulia Corina Ciobotaru,
  • Daniela Oprea,
  • Constantin Claudiu Ciobotaru and
  • Teodor Adrian Enache

15 December 2023

Technological progress has led to the development of analytical tools that promise a huge socio-economic impact on our daily lives and an improved quality of life for all. The use of plant extract synthesized nanoparticles in the development and fabr...

  • Article
  • Open Access
3 Citations
2,738 Views
19 Pages

Antibody Profiling: Kinetics with Native Biomarkers for Diagnostic Assay and Drug Developments

  • Ute Jucknischke,
  • Sebastian Friebe,
  • Markus Rehle,
  • Laura Quast and
  • Sven H. Schmidt

14 December 2023

Despite remarkable progress in applied Surface Plasmon Resonance (SPR)-based methods, concise monitoring of kinetic properties for native biomarkers from patient samples is still lacking. Not only are low concentrations of native targets in patient s...

  • Article
  • Open Access
15 Citations
3,557 Views
12 Pages

A Point-of-Care Testing Device Utilizing Graphene-Enhanced Fiber Optic SPR Sensor for Real-Time Detection of Infectious Pathogens

  • Shiyu Jiang,
  • Siyu Qian,
  • Shunning Zhu,
  • Jinxin Lu,
  • Yunxin Hu,
  • Cheng Zhang,
  • Yikai Geng,
  • Xuefeng Chen,
  • Ying Guo and
  • Zhaoliang Chen
  • + 3 authors

14 December 2023

Timely detection of highly infectious pathogens is essential for preventing and controlling public health risks. However, most traditional testing instruments require multiple tedious steps and ultimately testing in hospitals and third-party laborato...

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Biosensors - ISSN 2079-6374