Recent Progress in Bioplasmonics Technologies

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 2592

Special Issue Editors


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Guest Editor
Laboratory of Nano-photonics and Biosensors, Institute of Electro-Optical Engineering/ Department of Life Science, National Taiwan Normal University, Applied Science Building 3F, Inst. of Elec.-Opti. Eng., No. 88, Sec. 4, Ting-Chou Road, Wenshan Dist., Taipei 11677, Taiwan
Interests: optical biosensing; plasmonics; nanophotonics; organic optoelectronic devices integrated biosensor design; BioMEMS; optical system integration; advanced 2D materials synthesis and nanofabrication; DNA biosensors; microRNA biosensors; exosome biosensors
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Research and Development, illumina, Inc. 29 Woodlands Industrial Park E1 North Tech, Lobby 3, #02-13/18, Singapore 757716, Singapore
Interests: super-resolution microscopy; nanophotonics; surface plasmon resonance; Raman spectroscope; nanofabrication; biosensor; droplet microfluidics; optical tweezers; single-cell manipulation; isothermal amplification for infectious pathogen detection; immunoassay for cancer marker monitoring; high-throughput single-cell screening for synthetic biology; biomolecule sensing technology integration

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Guest Editor
Proteins and Tissue Engineering Lab, Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes. No. 35, Keyan Road, Zhunan Town, Miaoli County 35053, Taiwan
Interests: surface plasmon resonance; protein–protein interactions; protein orientation; transient binding; biosurface engineering; translational medicine; bone tissue engineering; microplastics; high-throughput screening; drug discovery; traditional Chinese medicine

Special Issue Information

Dear Colleagues,

I am very pleased to invite you to contribute to this Special Issue on bioplasmonics, which are emerging research subjects with various applications, from the biomedical field (from early diagnosis to therapy monitoring) to food quality control and environmental analyses.

Bioplasmonic sensors for biomedical applications are receiving increasing attention in scientific communities. Bioplasmonics have been used for fast, real-time, and label-free probing of biologically relevant analytes, where the main challenges are to detect small molecules at ultra-low concentrations and produce compact devices for point-of-care (PoC) analysis. Substituting existing bulky and expensive instrumentation with smart sensors that have a reduced size, lower cost-analysis systems, lab-on-a-chip, or paper-based devices is a challenge from the perspective of precision medicine, point-of-care analyses, and personalized pharmacological treatment.

Therefore, the rapid developments that have occurred in plasmonic biosensors, such as concepts in structural design, fabrication techniques, sensing materials, numerical simulation, gas sensing, and diagnostic applications, are contributing to significantly progressing the accurate and highly sensitive detection in future clinical applications.

Manuscripts presenting comprehensive reviews for the detailed analysis of sensor performance characteristics are welcome to showcase the current trends and challenges in plasmonic biosensing.

Scope of the Special Issue:

  • Plasmonic biosensors (prism-based, grating-based, waveguide-based etc.);
  • Plasmonic nanostructures, nano-antenna etc.;
  • Plasmonic instrumentation systems;
  • Plasmonic sensing material;
  • Plasmonic surface-enhanced Raman (SERS) spectroscopy;
  • Plasmonic biomedical applications.

This Special Issue plans to not only provide an overview of recent achievements, but also to stimulate ideas around current and future research in the bioplasmonic sensor field. Both original research and review articles are welcome.

Prof. Dr. Nan-Fu Chiu
Dr. Shih-Chung Wei
Dr. Guo-Chung Dong
Guest Editors

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Keywords

  • plasmonic biosensors
  • surface plasmon resonance (SPR)
  • localized surface plasmon resonance (LSPR)
  • SPR biosensors
  • sensing materials
  • environmental monitoring and diagnostic applications

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Published Papers (1 paper)

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Research

13 pages, 6128 KiB  
Article
A Novel Aptamer Biosensor Based on a Localized Surface Plasmon Resonance Sensing Chip for High-Sensitivity and Rapid Enrofloxacin Detection
by Pan Wang, Liyun Ding, Yumei Zhang and Xingdong Jiang
Biosensors 2023, 13(12), 1027; https://doi.org/10.3390/bios13121027 - 13 Dec 2023
Cited by 2 | Viewed by 1729
Abstract
Enrofloxacin, a fluoroquinolone widely used in animal husbandry, presents environmental and human health hazards due to its stability and incomplete hydrolysis leading to residue accumulation. To address this concern, a highly sensitive aptamer biosensor utilizing a localized surface plasmon resonance (LSPR) sensing chip [...] Read more.
Enrofloxacin, a fluoroquinolone widely used in animal husbandry, presents environmental and human health hazards due to its stability and incomplete hydrolysis leading to residue accumulation. To address this concern, a highly sensitive aptamer biosensor utilizing a localized surface plasmon resonance (LSPR) sensing chip and microfluidic technology was developed for rapid enrofloxacin residue detection. AuNPs were prepared by the seed method and the AuNPs-Apt complexes were immobilized on the chip by the sulfhydryl groups modified on the end of the aptamer. The properties and morphologies of the sensing chip and AuNPs-Apt complexes were characterized by Fourier transform infrared spectroscopy (FTIR), UV-Vis spectrophotometer, and scanning electron microscope (SEM), respectively. The sensing chip was able to detect enrofloxacin in the range of 0.01–100 ng/mL with good linearity, and the relationship between the response of the sensing chip and the concentration was Δλ (nm) = 1.288log ConENR (ng/mL) + 5.245 (R2 = 0.99), with the limit of detection being 0.001 ng/mL. The anti-interference, repeatability, and selectivity of this sensing chip were studied in detail. Compared with other sensors, this novel aptamer biosensor based on AuNPs-Apt complexes is expected to achieve simple, stable, and economical application in the field of enrofloxacin detection. Full article
(This article belongs to the Special Issue Recent Progress in Bioplasmonics Technologies)
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