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Biosensors, Volume 14, Issue 1

January 2024 - 57 articles

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Cover Story: Developing new approaches for elucidating bacterial membrane interactions with antimicrobial molecules is critical for combatting antibiotic resistance. In this study, we built a planar Gram-positive membrane-based biosensor that preserves the diversity of native membrane components using bacterial membrane vesicles. This biomembrane-based sensor, compatible with common surfaces such as glass, quartz crystals, and polymeric electrodes, facilitates the multimodal assessment of drug–membrane interactions. By recapitulating the established interaction patterns of the antimicrobial compound daptomycin, we demonstrated the successful biophysical characterization of interactions between this membrane-acting compound and the Gram-positive membrane. View this paper

Articles (57)

  • Communication
  • Open Access
6 Citations
3,030 Views
12 Pages

A Multimode Microfiber Specklegram Biosensor for Measurement of CEACAM5 through AI Diagnosis

  • Yuhui Liu,
  • Weihao Lin,
  • Fang Zhao,
  • Yibin Liu,
  • Junhui Sun,
  • Jie Hu,
  • Jialong Li,
  • Jinna Chen,
  • Xuming Zhang and
  • Mang I. Vai
  • + 2 authors

22 January 2024

Carcinoembryonic antigen (CEACAM5), as a broad-spectrum tumor biomarker, plays a crucial role in analyzing the therapeutic efficacy and progression of cancer. Herein, we propose a novel biosensor based on specklegrams of tapered multimode fiber (MMF)...

  • Article
  • Open Access
9 Citations
3,536 Views
17 Pages

Sensing Levofloxacin with an RNA Aptamer as a Bioreceptor

  • Janice Kramat,
  • Leon Kraus,
  • Vincent J. Gunawan,
  • Elias Smyej,
  • Philipp Froehlich,
  • Tim E. Weber,
  • Dieter Spiehl,
  • Heinz Koeppl,
  • Andreas Blaeser and
  • Beatrix Suess

22 January 2024

To combat the growing threat of antibiotic resistance, environmental testing for antibiotic contamination is gaining an increasing role. This study aims to develop an easy-to-use assay for the detection of the fluoroquinolone antibiotic levofloxacin....

  • Review
  • Open Access
13 Citations
9,405 Views
24 Pages

Microfluidics in High-Throughput Drug Screening: Organ-on-a-Chip and C. elegans-Based Innovations

  • Sunhee Yoon,
  • Dilara Kilicarslan You,
  • Uiechan Jeong,
  • Mina Lee,
  • Eunhye Kim,
  • Tae-Joon Jeon and
  • Sun Min Kim

21 January 2024

The development of therapeutic interventions for diseases necessitates a crucial step known as drug screening, wherein potential substances with medicinal properties are rigorously evaluated. This process has undergone a transformative evolution, dri...

  • Article
  • Open Access
1 Citations
2,995 Views
17 Pages

20 January 2024

Introducing 3-aminotyrosine (aY), a noncanonical amino acid (ncAA), into green fluorescent protein (GFP)-like chromophores shows promise for achieving red-shifted fluorescence. However, inconsistent results, including undesired green fluorescent spec...

  • Article
  • Open Access
1 Citations
2,931 Views
16 Pages

Reagentless Vis-NIR Spectroscopy Point-of-Care for Feline Total White Blood Cell Counts

  • Teresa Guerra Barroso,
  • Carla Queirós,
  • Filipe Monteiro-Silva,
  • Filipe Santos,
  • António Hugo Gregório and
  • Rui Costa Martins

19 January 2024

Spectral point-of-care technology is reagentless with minimal sampling (<10 μL) and can be performed in real-time. White blood cells are non-dominant in blood and in spectral information, suffering significant interferences from dominant consti...

  • Article
  • Open Access
3 Citations
2,480 Views
14 Pages

Exploring the Hidden Complexity: Entropy Analysis in Pulse Oximetry of Female Athletes

  • Ana M. Cabanas,
  • Macarena Fuentes-Guajardo,
  • Nicolas Sáez,
  • Davidson D. Catalán,
  • Patricio O. Collao-Caiconte and
  • Pilar Martín-Escudero

19 January 2024

This study examines the relationship between physiological complexity, as measured by Approximate Entropy (ApEn) and Sample Entropy (SampEn), and fitness levels in female athletes. Our focus is on their association with maximal oxygen consumption (VO...

  • Communication
  • Open Access
11 Citations
2,684 Views
12 Pages

18 January 2024

A new fluorescent sensor for the detection of CN− was developed based on the conjugation of phenothiazine fluorophore and benzofuran unit. By the nucleophilic attacking of CN− to the fluoroacetylamino group in the sensor, the additional r...

  • Article
  • Open Access
17 Citations
3,550 Views
14 Pages

18 January 2024

Recently, significant progress has been made in the development of microdevices for point-of-care infectious disease detection. However, most microdevices only allow limited steps, such as DNA amplification on the chip, while sample preparation, such...

  • Article
  • Open Access
7 Citations
2,906 Views
14 Pages

Aggregation-Resistant, Turn-On-Off Fluorometric Sensing of Glutathione and Nickel (II) Using Vancomycin-Conjugated Gold Nanoparticles

  • Atul Kumar Tiwari,
  • Munesh Kumar Gupta,
  • Hari Prakash Yadav,
  • Roger J. Narayan and
  • Prem C. Pandey

16 January 2024

Glutathione (GSH) and nickel (II) cation have an indispensable role in various physiological processes, including preventing the oxidative damage of cells and acting as a cofactor for lipid metabolic enzymes. An imbalance in the physiological level o...

  • Article
  • Open Access
2 Citations
2,659 Views
15 Pages

A Path towards Timely VAP Diagnosis: Proof-of-Concept Study on Pyocyanin Sensing with Cu-Mg Doped Graphene Oxide

  • Mohammad Noorizadeh,
  • Mithra Geetha,
  • Faycal Bensaali,
  • Nader Meskin,
  • Kishor K. Sadasivuni,
  • Susu M. Zughaier,
  • Mahmoud Elgamal and
  • Ali Ait Hssain

16 January 2024

In response to the urgent requirement for rapid, precise, and cost-effective detection in intensive care units (ICUs) for ventilated patients, as well as the need to overcome the limitations of traditional detection methods, researchers have turned t...

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Biosensors - ISSN 2079-6374Creative Common CC BY license