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Journal of Clinical Medicine, Volume 12, Issue 8

April-2 2023 - 296 articles

Cover Story: The term “stable coronary artery disease” (CAD) has recently been replaced with “chronic coronary syndrome” (CCS). This new term has been developed based on a better understanding of the pathogenesis, the clinical characteristics, and the morbi-mortality associated with this condition as part of the dynamic spectrum of CAD. This has significant implications in the clinical management of CCS patients, which includes lifestyle adaptation, medical therapy targeting all the elements contributing to CAD progression (i.e., platelet aggregation, coagulation, dyslipidaemia, and systemic inflammation), and invasive strategies (i.e., revascularization). We sought to synthetize the place of revascularization in CCS patients according to the latest guidelines, the lessons learnt from recent trials on revascularization and medical therapy, and future perspectives. View this paper
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Articles (296)

  • Article
  • Open Access
27 Citations
4,479 Views
14 Pages

Impact of Pretreatment Systemic Inflammatory Markers on Treatment Persistence with Biologics and Conventional Systemic Therapy: A Retrospective Study of Patients with Psoriasis Vulgaris and Psoriatic Arthritis

  • Eiki Sugimoto,
  • Hiroki Matsuda,
  • Sayaka Shibata,
  • Yuka Mizuno,
  • Asumi Koyama,
  • Lixin Li,
  • Haruka Taira,
  • Yukiko Ito,
  • Kentaro Awaji and
  • Takashi Yamashita
  • + 1 author

21 April 2023

Systemic inflammation plays a central role in the pathophysiology of psoriasis. This study examined accessible systemic inflammatory markers in patients with psoriasis vulgaris and psoriatic arthritis. We aimed to evaluate their association with psor...

  • Review
  • Open Access
10 Citations
4,474 Views
12 Pages

21 April 2023

High myopia is a significant public health issue globally and in the United States (US), where it affects ~4% of the population or 13 million people. This is a potentially blinding condition, but complications can be prevented with early intervention...

  • Review
  • Open Access
9 Citations
4,060 Views
21 Pages

Potential Role of Innate Lymphoid Cells in the Pathogenesis and Treatment of Skin Diseases

  • Francesco Borgia,
  • Federica Li Pomi,
  • Clara Alessandrello,
  • Mario Vaccaro and
  • Sebastiano Gangemi

21 April 2023

Group 2 innate lymphoid cells (ILC2s) are lymphoid cells that are resident in mucosal tissues, especially the skin, which, once stimulated by epithelial cell-derived cytokines, release IL-5, IL-13, and IL-4, as the effectors of type 2 immune response...

  • Article
  • Open Access
5 Citations
2,525 Views
20 Pages

Validation of “Neurit.Space”: Three Digital Tests for the Neuropsychological Evaluation of Unilateral Spatial Neglect

  • Gemma Massetti,
  • Federica Albini,
  • Carlotta Casati,
  • Carlo Toneatto,
  • Stefano Terruzzi,
  • Roberta Etzi,
  • Luigi Tesio,
  • Alberto Gallace and
  • Giuseppe Vallar

21 April 2023

Patients suffering from Unilateral Spatial Neglect (USN) fail to pay attention to, respond to, and report sensory events occurring in the contralesional side of space. The traditional neuropsychological assessment of USN is based on paper-and-pencil...

  • Article
  • Open Access
1 Citations
1,712 Views
9 Pages

Anatomical Analysis of the Gonadal Veins and Spine in Lateral Lumbar Interbody Fusion

  • Yujiro Kagami,
  • Hiroaki Nakashima,
  • Kotaro Satake,
  • Kenyu Ito,
  • Mikito Tsushima,
  • Naoki Segi,
  • Hiroyuki Tomita,
  • Jun Ouchida,
  • Yoshinori Morita and
  • Yukihito Ode
  • + 2 authors

21 April 2023

Background: The current study aimed to investigate the anatomical position of the gonadal veins (GVs) from the viewpoint of spine surgery and the risk factors associated with lateral lumbar interbody fusion (LLIF). Methods: This retrospective study i...

  • Article
  • Open Access
3 Citations
2,221 Views
13 Pages

21 April 2023

To date, few studies have examined changes in waist circumference and cardiovascular risk profile (CVRP) after autologous breast reconstruction. Therefore, this study aimed to investigate the effect of flap surgery using autologous tissue on waist ci...

  • Review
  • Open Access
8 Citations
10,329 Views
16 Pages

Malignant Bone and Soft Tissue Lesions of the Foot

  • Andrea Angelini,
  • Carlo Biz,
  • Mariachiara Cerchiaro,
  • Valentina Longhi and
  • Pietro Ruggieri

21 April 2023

Malignant tumors of the foot are rare pathologies that can involve the skin, soft tissue, or bone. Due to their rarity, they are often misdiagnosed, resulting in inadequate excision and poor outcomes. A correct approach with a careful examination and...

  • Systematic Review
  • Open Access
18 Citations
10,422 Views
14 Pages

Intense Pulsed Light Therapy in the Treatment of Dry Eye Diseases: A Systematic Review and Meta-Analysis

  • Lilian Demolin,
  • Majda Es-Safi,
  • Muhammad Shahnawaz Soyfoo and
  • Elie Motulsky

21 April 2023

Background: Intense pulsed light therapy (IPL) is a recently developed way of treating dry eye disease (DED). During the last decade, there was a multiplication of trials studying IPL efficacy. The goal of this review is to summarize the most importa...

  • Systematic Review
  • Open Access
10 Citations
3,139 Views
23 Pages

21 April 2023

Background: existing trials on the role of clinical pharmacists in managing chronic disease patients have focused on variety of interventions, including preparing patients for the transition from hospital to home. However, little quantitative evidenc...

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J. Clin. Med. - ISSN 2077-0383