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Journal of Clinical Medicine, Volume 12, Issue 8

2023 April-2 - 296 articles

Cover Story: The term “stable coronary artery disease” (CAD) has recently been replaced with “chronic coronary syndrome” (CCS). This new term has been developed based on a better understanding of the pathogenesis, the clinical characteristics, and the morbi-mortality associated with this condition as part of the dynamic spectrum of CAD. This has significant implications in the clinical management of CCS patients, which includes lifestyle adaptation, medical therapy targeting all the elements contributing to CAD progression (i.e., platelet aggregation, coagulation, dyslipidaemia, and systemic inflammation), and invasive strategies (i.e., revascularization). We sought to synthetize the place of revascularization in CCS patients according to the latest guidelines, the lessons learnt from recent trials on revascularization and medical therapy, and future perspectives. View this paper
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Articles (296)

  • Article
  • Open Access
41 Citations
5,389 Views
14 Pages

Impact of Pretreatment Systemic Inflammatory Markers on Treatment Persistence with Biologics and Conventional Systemic Therapy: A Retrospective Study of Patients with Psoriasis Vulgaris and Psoriatic Arthritis

  • Eiki Sugimoto,
  • Hiroki Matsuda,
  • Sayaka Shibata,
  • Yuka Mizuno,
  • Asumi Koyama,
  • Lixin Li,
  • Haruka Taira,
  • Yukiko Ito,
  • Kentaro Awaji and
  • Shinichi Sato
  • + 1 author

21 April 2023

Systemic inflammation plays a central role in the pathophysiology of psoriasis. This study examined accessible systemic inflammatory markers in patients with psoriasis vulgaris and psoriatic arthritis. We aimed to evaluate their association with psor...

(This article belongs to the Special Issue Psoriasis and Psoriatic Arthritis: How to Treat in the Era of Biologics and Small Molecule Inhibitors: 2nd Edition)
  • Review
  • Open Access
14 Citations
5,924 Views
12 Pages

21 April 2023

High myopia is a significant public health issue globally and in the United States (US), where it affects ~4% of the population or 13 million people. This is a potentially blinding condition, but complications can be prevented with early intervention...

(This article belongs to the Special Issue Risk Factors and Management Approaches to Reduce Disparities in Eye Diseases)
  • Review
  • Open Access
12 Citations
4,866 Views
21 Pages

Potential Role of Innate Lymphoid Cells in the Pathogenesis and Treatment of Skin Diseases

  • Francesco Borgia,
  • Federica Li Pomi,
  • Clara Alessandrello,
  • Mario Vaccaro and
  • Sebastiano Gangemi

21 April 2023

Group 2 innate lymphoid cells (ILC2s) are lymphoid cells that are resident in mucosal tissues, especially the skin, which, once stimulated by epithelial cell-derived cytokines, release IL-5, IL-13, and IL-4, as the effectors of type 2 immune response...

(This article belongs to the Special Issue Clinical Management of Allergic and Inflammatory Skin Diseases: A Diagnostic and Therapeutic Perspective)
  • Article
  • Open Access
7 Citations
3,248 Views
20 Pages

Validation of “Neurit.Space”: Three Digital Tests for the Neuropsychological Evaluation of Unilateral Spatial Neglect

  • Gemma Massetti,
  • Federica Albini,
  • Carlotta Casati,
  • Carlo Toneatto,
  • Stefano Terruzzi,
  • Roberta Etzi,
  • Luigi Tesio,
  • Alberto Gallace and
  • Giuseppe Vallar

21 April 2023

Patients suffering from Unilateral Spatial Neglect (USN) fail to pay attention to, respond to, and report sensory events occurring in the contralesional side of space. The traditional neuropsychological assessment of USN is based on paper-and-pencil...

(This article belongs to the Special Issue Neuropsychological Assessment: Past and Future)
  • Article
  • Open Access
2 Citations
2,231 Views
9 Pages

Anatomical Analysis of the Gonadal Veins and Spine in Lateral Lumbar Interbody Fusion

  • Yujiro Kagami,
  • Hiroaki Nakashima,
  • Kotaro Satake,
  • Kenyu Ito,
  • Mikito Tsushima,
  • Naoki Segi,
  • Hiroyuki Tomita,
  • Jun Ouchida,
  • Yoshinori Morita and
  • Tokumi Kanemura
  • + 2 authors

21 April 2023

Background: The current study aimed to investigate the anatomical position of the gonadal veins (GVs) from the viewpoint of spine surgery and the risk factors associated with lateral lumbar interbody fusion (LLIF). Methods: This retrospective study i...

(This article belongs to the Special Issue Lumbar Spine Surgery: Causes, Complications and Management)
  • Article
  • Open Access
5 Citations
2,630 Views
13 Pages

21 April 2023

To date, few studies have examined changes in waist circumference and cardiovascular risk profile (CVRP) after autologous breast reconstruction. Therefore, this study aimed to investigate the effect of flap surgery using autologous tissue on waist ci...

(This article belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
  • Review
  • Open Access
11 Citations
13,729 Views
16 Pages

Malignant Bone and Soft Tissue Lesions of the Foot

  • Andrea Angelini,
  • Carlo Biz,
  • Mariachiara Cerchiaro,
  • Valentina Longhi and
  • Pietro Ruggieri

21 April 2023

Malignant tumors of the foot are rare pathologies that can involve the skin, soft tissue, or bone. Due to their rarity, they are often misdiagnosed, resulting in inadequate excision and poor outcomes. A correct approach with a careful examination and...

(This article belongs to the Special Issue Updates in the Orthopedic Management of Foot Disorders)
  • Systematic Review
  • Open Access
23 Citations
12,634 Views
14 Pages

Intense Pulsed Light Therapy in the Treatment of Dry Eye Diseases: A Systematic Review and Meta-Analysis

  • Lilian Demolin,
  • Majda Es-Safi,
  • Muhammad Shahnawaz Soyfoo and
  • Elie Motulsky

21 April 2023

Background: Intense pulsed light therapy (IPL) is a recently developed way of treating dry eye disease (DED). During the last decade, there was a multiplication of trials studying IPL efficacy. The goal of this review is to summarize the most importa...

(This article belongs to the Section Ophthalmology)
  • Systematic Review
  • Open Access
15 Citations
3,906 Views
23 Pages

21 April 2023

Background: existing trials on the role of clinical pharmacists in managing chronic disease patients have focused on variety of interventions, including preparing patients for the transition from hospital to home. However, little quantitative evidenc...

(This article belongs to the Special Issue Advances in Acute and Chronic Heart Failure)
  • Article
  • Open Access
2,625 Views
11 Pages

Optimal Heart Rate May Improve Systolic and Diastolic Function in Patients with Fontan Circulation

  • Keiichi Hirono,
  • Teruhiko Imamura,
  • Kaori Tsuboi,
  • Shinya Takarada,
  • Mako Okabe,
  • Hideyuki Nakaoka,
  • Keijiro Ibuki and
  • Sayaka Ozawa

21 April 2023

(1) Background: The optimal heart rate, at which the E-wave and A-wave stand adjacent without any overlaps in the Doppler transmitral flow echocardiography, is associated with maximum cardiac output and favorable clinical outcomes in adult patients w...

(This article belongs to the Special Issue Congenital Heart Disease: Clinical Practice, Prognosis and Outcome)
  • Article
  • Open Access
15 Citations
10,606 Views
8 Pages

Risk Factors for Perineal Wound Breakdown in Early Postpartum: A Retrospective Case–Control Study

  • Amandine Puissegur,
  • Marie Accoceberry,
  • Marion Rouzaire,
  • Bruno Pereira,
  • Marie Herault,
  • Clément Bruhat,
  • Amélie Delabaere and
  • Denis Gallot

21 April 2023

We conducted a retrospective case–control study in patients presenting a perineal tear (second degree or higher) or episiotomy complicated by wound breakdown during maternity stay to identify risk factors associated with wound breakdown in earl...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
4 Citations
2,655 Views
10 Pages

Identification of Distinct Clinical Phenotypes of Critically Ill COVID-19 Patients: Results from a Cohort Observational Study

  • José Pedro Cidade,
  • Vicente Cés de Souza Dantas,
  • Alessandra de Figueiredo Thompson,
  • Renata Carnevale Carneiro Chermont de Miranda,
  • Rafaela Mamfrim,
  • Henrique Caroli,
  • Gabriela Escudini,
  • Natalia Oliveira,
  • Taiza Castro and
  • Pedro Póvoa

21 April 2023

Purpose: COVID-19 presents complex pathophysiology, and evidence collected points towards an intricate interaction between viral-dependent and individual immunological mechanisms. Identifying phenotypes through clinical and biological markers may pro...

(This article belongs to the Special Issue Intensive Care Management of COVID-19 Patients)
  • Article
  • Open Access
2,138 Views
11 Pages

21 April 2023

(1) Background: In ophthalmic surgery, white light is mostly applied to illuminate the intraocular space, and ophthalmologists are comfortable working with it. Diaphanoscopic illumination changes the spectral composition of light, resulting in a chan...

(This article belongs to the Section Ophthalmology)
  • Brief Report
  • Open Access
2 Citations
2,568 Views
8 Pages

Getting It Right in Obstructive Lung Disease

  • Annalisa Carlucci and
  • Barbara Fusar Poli

21 April 2023

Chronic hypercapnic respiratory failure in obstructive lung diseases may benefit from nocturnal Home non-invasive ventilation (HNIV). It has been shown that in patients with persistence of hypercapnia after an acute episode of chronic obstructive pul...

(This article belongs to the Special Issue Non-invasive Respiratory Support: How to Get It Right in Clinical Medicine—Volume I)
  • Review
  • Open Access
4 Citations
3,321 Views
15 Pages

21 April 2023

For decades, trabeculectomy (TE) was considered the gold standard for surgical treatment of open-angle glaucoma owing to its powerful intraocular pressure (IOP)-lowering potency. However, owing to the invasive nature and high-risk profile of TE, this...

(This article belongs to the Special Issue Advances in Glaucoma Surgery)
  • Article
  • Open Access
3 Citations
2,494 Views
18 Pages

21 April 2023

(I) Introduction: The use of Doppler ultrasound allows us to indirectly assess the effect of increased intrarenal pressure on renal blood flow during retrograde intrarenal surgery (RIRS). On the basis of vascular flow spectra from selected blood vess...

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
7 Citations
3,285 Views
10 Pages

Coronary Artery Disease and Prognosis of Heart Failure with Reduced Ejection Fraction

  • Lourdes Vicent,
  • Jesús Álvarez-García,
  • Rafael Vazquez-Garcia,
  • José R. González-Juanatey,
  • Miguel Rivera,
  • Javier Segovia,
  • Domingo Pascual-Figal,
  • Ramón Bover,
  • Fernando Worner and
  • Manuel Martínez-Sellés
  • + 2 authors

21 April 2023

Our aim was to determine the prognostic impact of coronary artery disease (CAD) on heart failure with reduced ejection fraction (HFrEF) mortality and readmissions. From a prospective multicenter registry that included 1831 patients hospitalized due t...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
5 Citations
2,803 Views
13 Pages

Deprescribing Strategies: A Prospective Study on Proton Pump Inhibitors

  • Giulia Calvini,
  • Giammarco Baiardi,
  • Francesca Mattioli,
  • Giulia Milano,
  • Francesca Calautti,
  • Alessia Zunino,
  • Carla Elda Fraguglia,
  • Fabio Caccavale,
  • Francesca Lantieri and
  • Giancarlo Antonucci

21 April 2023

Proton pump inhibitors (PPIs) are among the most controversially prescribed drugs in polypharmacy. This observational prospective study assessed the PPI prescriptive trend during hospitalization before and after implementation of a prescribing/depres...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
10 Citations
3,457 Views
16 Pages

The Interaction Effect of Anti-RgpA and Anti-PPAD Antibody Titers: An Indicator for Rheumatoid Arthritis Diagnosis

  • Diana Marcela Castillo,
  • Gloria Inés Lafaurie,
  • Consuelo Romero-Sánchez,
  • Nathaly Andrea Delgadillo,
  • Yormaris Castillo,
  • Wilson Bautista-Molano,
  • César Pacheco-Tena,
  • Juan Manuel Bello-Gualtero,
  • Philippe Chalem-Choueka and
  • Jaime E. Castellanos

21 April 2023

Porphyromonas gingivalis secretes virulence factors like Arg-gingipains and peptidyl arginine deiminase (PPAD), that are associated with rheumatoid arthritis (RA) pathogenesis. However, there is no information regarding the antibody titers for these...

(This article belongs to the Section Immunology & Rheumatology)
  • Review
  • Open Access
67 Citations
11,321 Views
20 Pages

Review of Osteoradionecrosis of the Jaw: Radiotherapy Modality, Technique, and Dose as Risk Factors

  • Erkan Topkan,
  • Ahmet Kucuk,
  • Efsun Somay,
  • Busra Yilmaz,
  • Berrin Pehlivan and
  • Ugur Selek

21 April 2023

Radiotherapy (RT) or concurrent chemoradiotherapy (CCRT) is the cornerstone of organ-sparing or adjuvant therapy for nearly all head and neck cancers. Unfortunately, aggressive RT or CCRT can result in severe late toxicities, such as osteoradionecros...

(This article belongs to the Special Issue Radiation Therapy for Head and Neck Cancer)
  • Article
  • Open Access
7 Citations
3,173 Views
13 Pages

Time Trends of Environmental and Socioeconomic Risk Factors in Patients with Inflammatory Bowel Disease over 40 Years: A Population-Based Inception Cohort 1977–2020

  • Panu Wetwittayakhlang,
  • Lorant Gonczi,
  • Petra A. Golovics,
  • Zsuzsanna Kurti,
  • Tunde Pandur,
  • Gyula David,
  • Zsuzsanna Erdelyi,
  • Istvan Szita,
  • Laszlo Lakatos and
  • Peter L. Lakatos

21 April 2023

Background: Data from population-based studies investigating trends in environmental factors associated with inflammatory bowel disease (IBD) is lacking. We aimed to assess long-term time trends of environmental and socioeconomic factors in IBD patie...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
3 Citations
3,236 Views
10 Pages

Sex-Related Differences among Adults with Hypertrophic Obstructive Cardiomyopathy Undergoing Transcoronary Ablation of Septal Hypertrophy

  • Emyal Alyaydin,
  • Julia Kirsten Vogel,
  • Peter Luedike,
  • Tienush Rassaf,
  • Rolf Alexander Jánosi and
  • Maria Papathanasiou

21 April 2023

(1) Background: The transcoronary ablation of septal hypertrophy (TASH) is an established therapy for hypertrophic obstructive cardiomyopathy (HOCM). Previous studies on this topic are characterised by a consistent male predominance and show a worse...

(This article belongs to the Special Issue Hypertrophic Cardiomyopathy—Current Challenges and Future Perspectives)
  • Article
  • Open Access
6 Citations
3,694 Views
13 Pages

The Inflammatory Bowel Disease—Disk Tool for Assessing Disability in Inflammatory Bowel Disease Patients: Validation of the Greek Version

  • Anastasia Katsoula,
  • Georgios Axiaris,
  • Afroditi Mpitouli,
  • Maria Palatianou,
  • Angeliki Christidou,
  • Nikolaos Dimitriadis,
  • Andreas Nakos,
  • Ploutarchos Pastras,
  • Panagiotis Kourkoulis and
  • Olga Giouleme
  • + 36 authors

21 April 2023

Background: The Inflammatory Bowel Disease-Disk (IBD-Disk) is a physician-administered tool that evaluates the functional status of patients with Inflammatory Bowel Disease (IBD). The aim of our study was to validate the content of the IBD-Disk in a...

(This article belongs to the Special Issue New Proactive Approaches and Precision Medicine in Crohn's Disease)
  • Article
  • Open Access
7 Citations
3,127 Views
14 Pages

Antegrade Intramedullary Femoral Lengthening and Distal Temporary Hemiepiphysiodesis for Combined Correction of Leg Length Discrepancy and Coronal Angular Deformity in Skeletally Immature Patients

  • Andrea Laufer,
  • Adrien Frommer,
  • Georg Gosheger,
  • Gregor Toporowski,
  • Jan Duedal Rölfing,
  • Carina Antfang,
  • Robert Roedl and
  • Bjoern Vogt

21 April 2023

Leg length discrepancies (LLD) are frequently associated with coronal malalignment. Temporary hemiepiphysiodesis (HED) is a well-established procedure for the correction of limb malalignment in skeletally immature patients. For treatment of LLD >...

(This article belongs to the Special Issue Deformity Correction, Bone Lengthening and Correction Osteotomies of the Lower Limb)
  • Article
  • Open Access
18 Citations
3,499 Views
15 Pages

Transalbugineal Artificial Urinary Sphincter: A Refined Implantation Technique to Improve Surgical Outcomes

  • Emilio Sacco,
  • Filippo Marino,
  • Carlo Gandi,
  • Riccardo Bientinesi,
  • Angelo Totaro,
  • Stefano Moretto,
  • Filippo Gavi,
  • Marco Campetella and
  • Marco Racioppi

21 April 2023

The artificial urinary sphincter (AUS) implantation is an effective treatment of post-prostatectomy urinary incontinence (PPI). Still, it may result in troublesome complications such as intraoperative urethral lesion and postoperative erosion. Based...

(This article belongs to the Special Issue Latest Advances in Urinary Incontinence)
  • Article
  • Open Access
2 Citations
2,475 Views
11 Pages

Use of Recombinant Activated Factor VII in Bleeding Lung Transplant Patients Undergoing Perioperative ECMO Therapy

  • Daniel Laxar,
  • Eva Schaden,
  • Marion Wiegele,
  • Konrad Hötzenecker,
  • Stefan Schwarz and
  • Johannes Gratz

21 April 2023

Background: Hemostasis in critically ill patients represents a fragile balance between hypocoagulation and hypercoagulation, and is influenced by various factors. Perioperative use of extracorporeal membrane oxygenation (ECMO)—increasingly used...

(This article belongs to the Special Issue Extracorporeal Membrane Oxygenation (ECMO): Current Progress and Clinical Challenges)
  • Article
  • Open Access
9 Citations
5,931 Views
15 Pages

Syringomyelia Associated with Chiari 1 Malformation in Adults: Positive Outcome Predictors after Posterior Fossa Decompression with Duraplasty

  • Palma Ciaramitaro,
  • Giuseppe Migliaretti,
  • Marilena Ferraris,
  • Andrea Garnero,
  • Giovanni Morana,
  • Paolo Carucci,
  • Ilaria Stura,
  • Fulvio Massaro and
  • Diego Garbossa

21 April 2023

Background: Syringomyelia (Syr) in patients with Chiari 1 malformation (CM1) may be attributable to abnormal dynamics of cerebrospinal fluid (CSF) in the upper cervical segment; fourth ventricle enlargement has been reported in association with a wor...

(This article belongs to the Special Issue Chiari 1 Malformation, Syringomyelia and Related Disorders: Advances in Diagnosis and Treatment for Adults and Children)
  • Editorial
  • Open Access
31 Citations
6,108 Views
4 Pages

Revolutionizing Chronic Kidney Disease Management with Machine Learning and Artificial Intelligence

  • Pajaree Krisanapan,
  • Supawit Tangpanithandee,
  • Charat Thongprayoon,
  • Pattharawin Pattharanitima and
  • Wisit Cheungpasitporn

21 April 2023

Chronic kidney disease (CKD) poses a significant public health challenge, affecting approximately 11% to 13% of the global population [...]

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
13 Citations
3,307 Views
11 Pages

Effect of Hemolysis Regarding the Characterization and Prognostic Relevance of Neuron Specific Enolase (NSE) after Cardiopulmonary Resuscitation with Extracorporeal Circulation (eCPR)

  • Franz Haertel,
  • Josephine Babst,
  • Christiane Bruening,
  • Jurgen Bogoviku,
  • Sylvia Otto,
  • Michael Fritzenwanger,
  • Thomas Gecks,
  • Henning Ebelt,
  • Sven Moebius-Winkler and
  • Ruediger Pfeifer
  • + 1 author

21 April 2023

Background: Hemolysis, a common adverse event associated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO), may affect neuron-specific enolase (NSE) levels and potentially confound its prognostic value in predicting neurological outcom...

(This article belongs to the Special Issue Mechanical Cardiopulmonary Assistance in the ICU)
  • Brief Report
  • Open Access
5 Citations
2,635 Views
10 Pages

Strain Analysis in Patients with Frequent Premature Ventricular Complexes and Preserved Left Ventricular Function Undergoing Ablation

  • Sina Jamé,
  • Zhigang Liu,
  • Theodore Kolias,
  • Jackson Liang,
  • Troy Labounty,
  • Michael Ghannam,
  • Rakesh Latchamsetty,
  • Krit Jongnarangsin,
  • Fred Morady and
  • Frank Bogun

21 April 2023

Background: Frequent premature ventricular complexes (PVCs) can cause PVC-induced cardiomyopathy. The value of PVC ablation in patients with preserved left ventricular function in the low–normal range (ejection fraction: 50–55%) is not established. S...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
4 Citations
3,548 Views
16 Pages

Prospective Evaluation of Magnetic Resonance Imaging Features of Magnesium-Based Alloy Screw Resorption in Pediatric Fractures

  • Stephan L. Waelti,
  • Simon Wildermuth,
  • Erik P. Willems,
  • Tim Fischer,
  • Tobias J. Dietrich,
  • Sebastian Leschka,
  • Christoph Matissek,
  • Thomas Krebs and
  • Stefan Markart

21 April 2023

Background: The resorption of magnesium-based alloy bioabsorbable screws results in the release of hydrogen gas, which can mimic infection and enter the growth plate. The screw itself and the released gas may also affect image quality. Objective: The...

(This article belongs to the Section Nuclear Medicine & Radiology)
  • Review
  • Open Access
9 Citations
4,814 Views
30 Pages

20 April 2023

Endometrial cancer (EC) is increasingly undermining female health worldwide, with poor survival rates for advanced or recurrent/metastatic diseases. The application of immune checkpoint inhibitors (ICIs) has opened a window of opportunity for patient...

(This article belongs to the Special Issue New Advances in Clinical Reproductive Medicine)
  • Article
  • Open Access
9 Citations
3,502 Views
13 Pages

A Multi-Modal AI-Driven Cohort Selection Tool to Predict Suboptimal Non-Responders to Aflibercept Loading-Phase for Neovascular Age-Related Macular Degeneration: PRECISE Study Report 1

  • Michal Chorev,
  • Jonas Haderlein,
  • Shruti Chandra,
  • Geeta Menon,
  • Benjamin J. L. Burton,
  • Ian Pearce,
  • Martin McKibbin,
  • Sridevi Thottarath,
  • Eleni Karatsai and
  • Sobha Sivaprasad
  • + 12 authors

20 April 2023

Patients diagnosed with exudative neovascular age-related macular degeneration are commonly treated with anti-vascular endothelial growth factor (anti-VEGF) agents. However, response to treatment is heterogeneous, without a clinical explanation. Pred...

(This article belongs to the Section Ophthalmology)
  • Review
  • Open Access
29 Citations
12,214 Views
19 Pages

20 April 2023

Background: Structured exercise as part of lifestyle modification plays an important role in the improvement of non-alcoholic fatty liver disease (NAFLD); however, its effectiveness has been shown to vary. This systematic review with meta-analysis in...

(This article belongs to the Special Issue Clinical Research Advances in Non-alcoholic Fatty Liver Disease)
  • Article
  • Open Access
6 Citations
3,143 Views
13 Pages

Factors Influencing Disabled Stroke Survivors’ Quality of Life in Rural China: Based on the Structural Characteristics and Psychometric Properties of the SF-36 Assessment

  • Qi Xu,
  • Dingzhao Zheng,
  • Shanjia Chen,
  • Yiqi He,
  • Zhenguo Lin,
  • Dong Yao,
  • Jiamei Wang,
  • Jiapei Zhao,
  • Longqiang Wu and
  • Tiebin Yan
  • + 2 authors

20 April 2023

Many stroke survivors’ quality of life is impaired. Few studies of factors influencing their quality of life have been based on the factors tested by the short form 36 instrument. This study did so with 308 physically disabled stroke survivors...

(This article belongs to the Section Clinical Rehabilitation)
  • Article
  • Open Access
2 Citations
2,347 Views
11 Pages

How Can We Best Measure Frailty in Cardiosurgical Patients?

  • Magdalena L. Laux,
  • Christian Braun,
  • Filip Schröter,
  • Daniela Weber,
  • Aiman Moldasheva,
  • Tilman Grune,
  • Roya Ostovar,
  • Martin Hartrumpf and
  • Johannes Maximilian Albes

20 April 2023

Background: Frailty is gaining importance in cardiothoracic surgery and is a risk factor for adverse outcomes and mortality. Various frailty scores have since been developed, but there is no consensus which to use for cardiac surgery. Methods: In an...

(This article belongs to the Section Cardiology)
  • Review
  • Open Access
8 Citations
5,804 Views
11 Pages

Developments in Post-Resuscitation Care for Out-of-Hospital Cardiac Arrests in Adults—A Narrative Review

  • Stephan Katzenschlager,
  • Erik Popp,
  • Jan Wnent,
  • Markus A. Weigand and
  • Jan-Thorsten Gräsner

20 April 2023

This review focuses on current developments in post-resuscitation care for adults with an out-of-hospital cardiac arrest (OHCA). As the incidence of OHCA is high and with a low percentage of survival, it remains a challenge to treat those who survive...

(This article belongs to the Special Issue Cardiopulmonary Resuscitation: Clinical Updates and Perspectives)
  • Article
  • Open Access
2 Citations
3,335 Views
12 Pages

Baseline Predictors of the Long-Term Insufficient Biochemical Response in Patients with Autoimmune Hepatitis: A Single Center Experience

  • Pierluigi Toniutto,
  • Michela Zorzi,
  • Lorenzo D’Alì,
  • Annarosa Cussigh,
  • Sara Cmet,
  • Davide Bitetto,
  • Ezio Fornasiere,
  • Elisa Fumolo,
  • Carla Di Loreto and
  • Edmondo Falleti

20 April 2023

The treatment response criteria in autoimmune hepatitis (AIH) have been recently updated. This study aimed to assess treatment responses in 39 (16 males) patients with AIH confirmed by histology. Prednisone added to azathioprine or mycophenolate was...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Systematic Review
  • Open Access
12 Citations
3,036 Views
10 Pages

Transoral Robotic Surgery in the Management of Submandibular Gland Sialoliths: A Systematic Review

  • Marta Rogalska,
  • Lukasz Antkowiak,
  • Anna Kasperczuk,
  • Wojciech Scierski and
  • Maciej Misiolek

20 April 2023

This study aimed to systematically review the literature to determine the efficacy and safety of transoral robotic surgery (TORS) in the management of submandibular gland (SMG) sialolithiasis. PubMed, Embase, and Cochrane were searched for English-la...

(This article belongs to the Special Issue Head and Neck Surgery: Clinical Updates and Perspectives)
  • Feature Paper
  • Article
  • Open Access
15 Citations
4,894 Views
15 Pages

Impact of COVID-19 Infection on Cardiorespiratory Fitness, Sleep, and Psychology of Endurance Athletes—CAESAR Study

  • Daniel Śliż,
  • Szczepan Wiecha,
  • Jakub S. Gąsior,
  • Przemysław Seweryn Kasiak,
  • Katarzyna Ulaszewska,
  • Marcin Lewandowski,
  • Marcin Barylski and
  • Artur Mamcarz

20 April 2023

COVID-19 has a deteriorating impact on health which is especially important for endurance athletes (EAs) who need to maintain continuity of training. The illness affects sleep and psychology, which influence sport performance. The aims of this study...

(This article belongs to the Special Issue The COVID-19 Pandemic and Mental Health: The Next Phase)
  • Article
  • Open Access
4 Citations
3,375 Views
9 Pages

20 April 2023

Introduction: Out-of-hospital cardiac arrest (OHCA) is complex, and risk stratification tools have the potential to include components other than clinical risk indicators, thus requiring extensive studies. Simple and accurate biomarkers for OHCA pati...

(This article belongs to the Special Issue Cardiac Arrest, Special Considerations for Emergency and Intensive Care)
  • Article
  • Open Access
3 Citations
2,103 Views
11 Pages

Pulmonary Recruitment Prior to Intraoperative Multiple Pulmonary Ground-Glass Nodule Localization Increases the Localization Accuracy—A Retrospective Study

  • Yu Hsiang Wang,
  • Pei Chin Su,
  • Hsu Chih Huang,
  • Kenneth Au,
  • Frank Cheau Feng Lin,
  • Chih Yi Chen,
  • Ming Chih Chou and
  • Jiun Yi Hsia

20 April 2023

The standard treatment for early-stage lung cancer is complete tumor excision by limited resection of the lung. Preoperative localization is used before video-assisted thoracoscopic surgery (VATS) to improve the accuracy of pulmonary nodule excision....

(This article belongs to the Section Respiratory Medicine)
  • Brief Report
  • Open Access
6 Citations
3,565 Views
9 Pages

Long-Term Outcomes of Nasopharyngeal Carcinoma by Epstein–Barr Virus Status in the Chinese Population: A Multicenter Investigation

  • Yudi Xiong,
  • Mengting Yuan,
  • Zhigang Liu,
  • Jing Huang,
  • Jianping Bi,
  • Guoliang Pi,
  • Ying Li,
  • Yanping Li,
  • Hanping He and
  • Guang Han
  • + 2 authors

20 April 2023

Background: Because the vast majority of nasopharyngeal carcinoma (NPC) in Chinese patients is a direct result of Epstein–Barr virus (EBV) infection, there is a dearth of data for EBV-negative patients in this population. This multicenter study...

(This article belongs to the Topic Biomarker Development and Application)
  • Article
  • Open Access
16 Citations
4,397 Views
11 Pages

Sleep Bruxism and Orofacial Pain in Patients with Sleep Disorders: A Controlled Cohort Study

  • Maria Lavinia Bartolucci,
  • Serena Incerti Parenti,
  • Francesco Bortolotti,
  • Veronica Della Godenza,
  • Stefano Vandi,
  • Fabio Pizza,
  • Giuseppe Plazzi and
  • Giulio Alessandri-Bonetti

20 April 2023

Background: The gold standard for the diagnosis of sleep bruxism (SB) is laboratory polysomnography (L-PSG) recording. However, many clinicians still define SB using patients’ self-assessment and/or clinical tooth wear (TW). The purpose of this...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
23 Citations
3,670 Views
10 Pages

20 April 2023

There is little knowledge of the effect of inflammatory markers on the prognoses of hematoma expansion (HE) in patients with intracranial hemorrhage (ICH). We evaluated the impact of neutrophil–lymphocyte ratio (NLR) and platelet–lymphocy...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
14 Citations
3,287 Views
11 Pages

Anxiety and Depressive Symptoms Correlated to Patient-Reported Outcome Measures after Rotator Cuff Repair: A Prospective Study in the Perioperative Period

  • Umile Giuseppe Longo,
  • Sergio De Salvatore,
  • Ilaria Piergentili,
  • Nicolò Panattoni,
  • Anna Marchetti,
  • Maria Grazia De Marinis and
  • Vincenzo Denaro

20 April 2023

Anxiety and depressive symptoms adversely affect surgical outcomes in patients with rotator cuff tear (RCT) undergoing surgical repair. Patients without a diagnosis of mood disorders, such as anxiety and depression, before rotator cuff repair (RCR) c...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
17 Citations
3,583 Views
13 Pages

Connection between Cardiac Fibrosis Biomarkers and Echocardiography Parameters in Advanced Chronic Kidney Disease Patients

  • Carina Ureche,
  • Gianina Dodi,
  • Alexandra Covic,
  • Alina Nedelcu,
  • Simona R. Volovăț,
  • Radu A. Sascău,
  • Cristian Stătescu and
  • Adrian Covic

20 April 2023

Background: Myocardial fibrosis represents a mainstay pathway in the pathophysiology of uremic cardiomyopathy. This process leads to structural and functional changes in the heart, which can be detected by echocardiography. The purpose of our study w...

(This article belongs to the Special Issue Cardiovascular Complications in Renal Diseases)
  • Article
  • Open Access
18 Citations
2,975 Views
12 Pages

One-Year Outcomes of PreserfloTM MicroShunt Implantation versus Trabeculectomy for Pseudoexfoliation Glaucoma

  • Matthias Nobl,
  • Clara Grün,
  • Stefan Kassumeh,
  • Siegfried Priglinger and
  • Marc J. Mackert

20 April 2023

This retrospective, single-center study evaluates the safety and efficacy of PreserfloTM MicroShunt (MicroShunt) implantations compared to trabeculectomies (TETs) in patients diagnosed with pseudoexfoliation glaucoma (PEXG). A total of 31 eyes from 2...

(This article belongs to the Special Issue Diagnosis, Treatment, and Prevention of Glaucoma)
  • Article
  • Open Access
10 Citations
9,079 Views
11 Pages

Clinical Relevance of Vaginal Cuff Dehiscence after Minimally Invasive versus Open Hysterectomy

  • Kyung Jin Eoh,
  • Young Joo Lee,
  • Eun Ji Nam,
  • Hye In Jung and
  • Young Tae Kim

20 April 2023

This study aimed to evaluate the clinical relevance of vaginal cuff dehiscence following a hysterectomy. Data were prospectively collected from all patients who underwent hysterectomies at a tertiary academic medical center between 2014 and 2018. The...

(This article belongs to the Section General Surgery)

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J. Clin. Med. - ISSN 2077-0383