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Vaccines, Volume 5, Issue 2

June 2017 - 7 articles

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Articles (7)

  • Article
  • Open Access
6 Citations
6,641 Views
8 Pages

Reemergence of Measles in the Americas: The Genotype B3 2011–2012 Outbreak in Ecuador

  • Nicole K. Le,
  • Rahul Mhaskar,
  • Ismael Hoare,
  • Mauricio Espinel,
  • María Fernanda Rivadeneira,
  • Sharad Malavade and
  • Ricardo Izurieta

This study characterizes a measles outbreak which occurred in Ecuador in 2011–2012, analyzing data from 3700 suspected cases of measles reported to Ecuador’s Ministry of Public Health. The study population had a large age range and included 333 confi...

  • Review
  • Open Access
46 Citations
30,341 Views
23 Pages

Disease Prevention: An Opportunity to Expand Edible Plant-Based Vaccines?

  • Christopher Concha,
  • Raúl Cañas,
  • Johan Macuer,
  • María José Torres,
  • Andrés A. Herrada,
  • Fabiola Jamett and
  • Cristian Ibáñez

The lethality of infectious diseases has decreased due to the implementation of crucial sanitary procedures such as vaccination. However, the resurgence of pathogenic diseases in different parts of the world has revealed the importance of identifying...

  • Article
  • Open Access
13 Citations
9,642 Views
19 Pages

The Potential Cost-Effectiveness of Pre-Exposure Prophylaxis Combined with HIV Vaccines in the United States

  • Blythe J. S. Adamson,
  • Josh J. Carlson,
  • James G. Kublin and
  • Louis P. Garrison

This economic evaluation aims to support policy-making on the combined use of pre-exposure prophylaxis (PrEP) with HIV vaccines in development by evaluating the potential cost-effectiveness of implementation that would support the design of clinical...

  • Article
  • Open Access
4 Citations
4,661 Views
15 Pages

Unexpected Infection Spikes in a Model of Respiratory Syncytial Virus Vaccination

  • Robert J. Smith,
  • Alexandra B. Hogan and
  • Geoffry N. Mercer

Respiratory Syncytial Virus (RSV) is an acute respiratory infection that infects millions of children and infants worldwide. Recent research has shown promise for the development of a vaccine, with a range of vaccine types now in clinical trials or p...

  • Communication
  • Open Access
13 Citations
5,214 Views
10 Pages

The Effect of Physicochemical Modification on the Function of Antibodies Induced by Anti-Nicotine Vaccine in Mice

  • Jennifer M. Thorn,
  • Keshab Bhattacharya,
  • Renata Crutcher,
  • Justin Sperry,
  • Colleen Isele,
  • Barbara Kelly,
  • Libbey Yates,
  • James Zobel,
  • Ningli Zhang and
  • Heather L. Davis
  • + 1 author

Smoking remains one of the major causes of morbidity and mortality worldwide. One approach to assisting smoking cessation is via anti-nicotine vaccines, composed of nicotine-like haptens conjugated to a carrier protein plus adjuvant(s). We have previ...

  • Article
  • Open Access
31 Citations
8,598 Views
15 Pages

Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax

  • Gustavo Cabral-Miranda,
  • Matthew D. Heath,
  • Mona O. Mohsen,
  • Ariane C. Gomes,
  • Paul Engeroff,
  • Amy Flaxman,
  • Fabiana M. S. Leoratti,
  • Aadil El-Turabi,
  • Arturo Reyes-Sandoval and
  • Murray A. Skinner
  • + 2 authors

Vaccination is the most effective prophylactic tool against infectious diseases. Despite continued efforts to control malaria, the disease still generally represents a significant unmet medical need. Microcrystalline tyrosine (MCT) is a well describe...

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Vaccines - ISSN 2076-393X