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Brain Sciences, Volume 13, Issue 8

August 2023 - 107 articles

Cover Story: Delayed intracranial hemorrhage is a rare kind of hemorrhagic complication following ventricular drainage procedures, occurring more than 48 hours after surgery. Though their pathophysiology remains unclear, a higher incidence has been demonstrated in patients with cerebrovascular diseases. We explore this unusual complication in a retrospective series of ten patients treated for chronic hydrocephalus after rupture of a brain arteriovenous malformation. Our series confirmed the poor prognosis of this complication, as four of our patients died, whereas three needed surgical management and the remaining three improved gradually with conservative management. These reports raise questions regarding the ideal management of hydrocephalus in patients with a history of AVM rupture. View this paper
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Articles (107)

  • Article
  • Open Access
10 Citations
3,155 Views
15 Pages

21 August 2023

Background: Hemodialysis (HD) patients have lower cognitive functioning and reduced physical fitness than age-matched healthy individuals. Clinicians typically do not recognize the declining cognitive performance in these patients; therefore, cogniti...

  • Case Report
  • Open Access
2,617 Views
10 Pages

21 August 2023

Higher brain dysfunction commonly occurs following traumatic brain injury (TBI), and may manifest in a social behavioral impairment which can significantly impede active social participation. We report two cases, one of voyeurism and the second of al...

  • Review
  • Open Access
37 Citations
4,025 Views
23 Pages

Emerging Paradigms in Inflammatory Disease Management: Exploring Bioactive Compounds and the Gut Microbiota

  • Tarek Benameur,
  • Chiara Porro,
  • Mohammed-Elfatih Twfieg,
  • Nassima Benameur,
  • Maria Antonietta Panaro,
  • Francesca Martina Filannino and
  • Abeir Hasan

21 August 2023

The human gut microbiota is a complex ecosystem of mutualistic microorganisms that play a critical role in maintaining human health through their individual interactions and with the host. The normal gastrointestinal microbiota plays a specific physi...

  • Article
  • Open Access
5 Citations
2,024 Views
13 Pages

The Influence of Transcranial Alternating Current Stimulation on Fatigue Resistance

  • Kayla A. De Guzman,
  • Richard J. Young,
  • Valentino Contini,
  • Eliza Clinton,
  • Ashley Hitchcock,
  • Zachary A. Riley and
  • Brach Poston

21 August 2023

Previous research has shown that some forms of non-invasive brain stimulation can increase fatigue resistance. The purpose of this study is to determine the influence of transcranial alternating current stimulation (tACS) on the time to task failure...

  • Article
  • Open Access
1 Citations
2,781 Views
17 Pages

Metabolomics Analysis of DRG and Serum in the CCI Model of Mice

  • Kaimei Lu,
  • Bin Fang,
  • Yuqi Liu,
  • Fangxia Xu,
  • Chengcheng Zhou,
  • Lijuan Wang,
  • Lianhua Chen and
  • Lina Huang

21 August 2023

Neuropathic pain (NP) is a chronic and intractable disease that is widely present in the general population. It causes painful behavior and even mood changes such as anxiety and depression by altering the metabolism of substances. However, there have...

  • Article
  • Open Access
4 Citations
2,390 Views
12 Pages

Elevated Plasma Levels of Mature Brain-Derived Neurotrophic Factor in Major Depressive Disorder Patients with Higher Suicidal Ideation

  • Haimei Li,
  • Miaomiao Zhao,
  • Chaonan Jiang,
  • Haoyang Zhao,
  • Congchong Wu,
  • Ying Li,
  • Shiyi Zhang,
  • Pengfeng Xu,
  • Tingting Mou and
  • Yi Xu
  • + 1 author

21 August 2023

Several pieces of evidence show that signaling via brain-derived neurotrophic factor (BDNF) and its receptor, tropomycin receptor kinase B (TrkB), as well as inflammation, play a crucial part in the pathophysiology of depression. The purpose of our s...

  • Article
  • Open Access
10 Citations
3,788 Views
18 Pages

Screening for Mild Cognitive Impairment with Speech Interaction Based on Virtual Reality and Wearable Devices

  • Ruixuan Wu,
  • Aoyu Li,
  • Chen Xue,
  • Jiali Chai,
  • Yan Qiang,
  • Juanjuan Zhao and
  • Long Wang

21 August 2023

Significant advances in sensor technology and virtual reality (VR) offer new possibilities for early and effective detection of mild cognitive impairment (MCI), and this wealth of data can improve the early detection and monitoring of patients. In th...

  • Review
  • Open Access
7 Citations
2,460 Views
17 Pages

Can Brain-Derived Neurotrophic Factor Be Considered a Biomarker for Bipolar Disorder? An Analysis of the Current Evidence

  • Gianmarco De Felice,
  • Mario Luciano,
  • Alessia Boiano,
  • Giulia Colangelo,
  • Pierluigi Catapano,
  • Bianca Della Rocca,
  • Maria Vita Lapadula,
  • Elena Piegari,
  • Claudia Toni and
  • Andrea Fiorillo

20 August 2023

Brain-derived neurotrophic factor (BDNF) plays a key role in brain development, contributing to neuronal survival and neuroplasticity. Previous works have found that BDNF is involved in several neurological or psychiatric diseases. In this review, we...

  • Article
  • Open Access
1 Citations
1,539 Views
12 Pages

19 August 2023

Objectives: Based on readily available demographic data, neuropsychological assessment results, and comorbidity data, we aimed to develop and validate a 3-year survival prediction model for patients with cognitive impairment. Methods: In this prospec...

  • Article
  • Open Access
5 Citations
2,150 Views
10 Pages

Individualized Vibrotactile Neurofeedback Training in Patients with Chronic Bilateral Vestibulopathy

  • Dietmar Basta,
  • Marcos Rossi-Izquierdo,
  • Kai Wonneberger,
  • Cibele Brugnera,
  • Roseli Saraiva Moreira Bittar,
  • Mário Edvin Greters,
  • Arne Ernst and
  • Andrés Soto-Varela

18 August 2023

Patients with bilateral vestibulopathy (BVP) suffer from postural imbalance during daily life conditions, which in turn leads to a high frequency of falls. Unfortunately, vestibular rehabilitation has only modest and somewhat inconsistent effects in...

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Brain Sci. - ISSN 2076-3425